Obstructive Sleep Apnea-hypopnea Syndrome and Severe Asthma: Advances and Challenges

doi:10.12114/j.issn.1007-9572.2023.0759

Abstract

Abstract:

Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS) and asthma are two prevalent chronic respiratory diseases. Recent research has revealed that OSAHS not only shares several common risk factors with asthma but also exhibits a high comorbidity rate with it. This mutual interaction complicates the course of both diseases and increases complexity to clinical diagnosis and treatment. This review aims to provide a comprehensive summary and analysis, from an epidemiological and pathophysiological perspective, of the research progress and challenges concerning the OSAHS comorbided with asthma, particularly in severe asthma.

Key words: Sleep apnea, obstructive, Asthma, Comorbidity, Risk factors, Review

摘要：

阻塞性睡眠呼吸暂停低通气综合征（OSAHS）和哮喘是两种发病率较高的慢性呼吸系统疾病。近年来研究显示，OSAHS不仅与哮喘存在多种共同的危险因素，两者的共病率也相对较高，并使彼此的疾病进程变得更加复杂，增加了临床诊疗的难度。本综述旨在从流行病学和病理生理学的角度对OSAHS合并哮喘（尤其是重症哮喘）的研究进展与面临的挑战进行总结与探讨。

关键词: 睡眠呼吸暂停，阻塞性, 哮喘, 共病现象, 危险因素, 综述

ZHU Yaming,DU Li,WANG Huanhui, et al. Obstructive Sleep Apnea-hypopnea Syndrome and Severe Asthma: Advances and Challenges[J]. Chinese General Practice, 2024, 27(25): 3192-3196. DOI: 10.12114/j.issn.1007-9572.2023.0759.
朱亚敏,杜莉,王焕辉等. 阻塞性睡眠呼吸暂停低通气综合征合并重症哮喘的研究现状和挑战[J]. 中国全科医学, 2024, 27(25): 3192-3196. DOI: 10.12114/j.issn.1007-9572.2023.0759.

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