Stroke is one of the leading causes of death and disability worldwide. The incidence of aphasia resulting from first-ever ischemic stroke is about 30%. Current guideline-recommended therapy is often challenging to achieve a satisfactory outcome, but numerous studies have shown that the treatment benefit could be increased if acupuncture therapy is used in a combined approach.

To give an overview of systematic reviews/meta-analyses of acupuncture-based treatment for post-stroke aphasia (PSA) .

Systematic reviews/meta-analyses of the efficacy of acupuncture-based treatment in PSA were searched in databases of CNKI, Wanfang Data, VIP, SinoMed, Cochrane Library, PubMed and EMBase from inception to July 2021. Literature enrollment and data extraction were performed by two researchers, respectively. The AMSTAR 2, PRISMA statement, and GRADE classification were used to evaluate methodological quality, the quality of reporting and the quality of evidence for outcome indicators, respectively. The results of overview were analysed in a comprehensive manner.

A total of 12 systematic reviews/meta-analyses were included. One was of moderate methodological quality, five were of low quality and six were of critically low. Mainly due to the absence of a description of the pre-design protocol, the quality of majority of studies was rated low or critically low. The 12 studies had PRISMA scores ranging from 17 to 25, 7 of which with scores of 20-25 were considered relatively complete, and 5 with scores of 17-19 were considered to have certain defects. Fifty-four pieces of evidence were summarized from the studies, 12 of which were rated as moderate by GRADE in terms of quality, 24 were rated as low, and 18 very low.

In accordance with the evidence of moderate quality, compared with speech rehabilitation alone, acupuncture with speech rehabilitation could better improve the speech impairment, auditory comprehension, repetition and reading ability, and acupuncture-based treatment could better improve the overall clinical response in patients with PSA, so acupuncture therapy is recommended for clinical use. However, the efficacy of acupuncture in PSA is needs to be verified further by clinical evidence derived from more high-quality original studies using a strict evidence development process.

卒中是世界范围内导致患者死亡和残疾的主要原因之一，首次缺血性卒中后失语症发生率为30%。目前指南推荐疗法通常难以获得满意疗效。诸多研究表明，针刺联合疗法可增加患者获益。

对针刺为主导疗法治疗卒中后失语症的系统评价/Meta分析进行再评价。

计算机检索中国知网（CNKI）、万方数据知识服务平台（Wanfang Data）、维普网（VIP）、中国生物医学文献服务系统（SinoMed）、Cochrane Library、PubMed和EMBase数据库，搜集针刺治疗卒中后失语症疗效的系统评价/Meta分析，检索时间为建库至2021年7月。由2名研究者分别进行文献筛选和资料提取。采用AMSTAR 2工具、PRISMA声明、GRADE分级评价纳入研究的方法学质量、报告质量和结局指标的证据质量，对结果进行综合分析。

共纳入12篇系统评价/Meta分析，其中1篇方法学质量为中质量，5篇为低质量，6篇为极低质量，主要由于研究者在系统评价/Meta分析中未对前期设计方案进行说明，该项关键条目缺失导致多数研究为低质量或极低质量。12篇文献PRISMA得分为17~25分，其中20~25分有7篇，报告相对完整；17~19分有5篇，报告存在一定缺陷。GRADE分级结果显示，12个为中级证据，24个为低级证据，18个为极低级证据。

针刺联合语言康复等疗法与单纯语言康复等疗法相比，在改善卒中后失语症患者语言障碍严重程度、听语理解、复述及阅读能力方面，以及以针刺为主导疗法在提高卒中后失语症患者临床有效率方面，证据质量均为中级，推荐临床使用。在其他方面，今后仍有必要进行更多高质量的原始研究，严格证据形成过程，为卒中后失语症的针刺康复提供更有力的循证依据。