Blood Pressure Control Goals in Elderly
Patients with Hypertension：Evidence from Latest Clinical Studies

doi:10.12114/j.issn.1007-9572.2022.01.303

Chinese General Practice ›› 2022, Vol. 25 ›› Issue (11): 1305-1308.DOI: 10.12114/j.issn.1007-9572.2022.01.303

• Clinical Decision Support • Previous Articles Next Articles

Blood Pressure Control Goals in Elderly Patients with Hypertension：Evidence from Latest Clinical Studies

1.Department of Geriatric Cardiology，Hebei General Hospital，Shijiazhuang 050051，China
2.Graduate School of Hebei Medical University，Shijiazhuang 050000，China
*Corresponding author：GUO Yifang，Professor；E-mail：guoyifang@hotmail.com

Received:2021-11-18 Revised:2022-02-23 Published:2022-04-15 Online:2022-03-28

从最新临床研究证据看老年高血压患者的血压控制目标

¹050051　河北省石家庄市，河北省人民医院老年心血管内科
²050000　河北省石家庄市，河北医科大学研究生院

通讯作者: 郭艺芳
基金资助:
河北省重点研发计划(19277787D);河北省创新能力提升计划(199776249D)

Abstract

Abstract:

Due to the lack of relevant research evidence, the optimal blood pressure target in elderly hypertensive patients has been controversial for a long time. Many scholars believe that the elderly have poor tolerance to antihypertensive treatment, so their blood pressure control goal should bemore relaxed. However, the latest research evidence published in recent years shows that there may be more benefits from controlling systolic blood pressure in older adults to <130 mmHg. It is expected that these new research conclusions will have an important impact on the revision of guidelines in the future.

Key words: Hypertension, Guidelines, Antihypertensive therapy, Aged

摘要：

由于相关研究证据较少，长期以来老年高血压患者的血压控制目标一直存在争议。很多学者认为，老年高血压患者对于降压治疗的耐受性较差，因而其血压控制目标应该更宽松。但近年来发表的最新研究证据表明，将老年高血压患者收缩压控制在<130 mm Hg（1 mm Hg=0.133 kPa）可以更多获益。预期这些新研究结论将会对未来国内外指南的修订产生重要影响。

关键词: 高血压, 指南, 降压治疗, 老年人

CLC Number:

R544.1

LIU Kaixuan, GUO Yifang.

Blood Pressure Control Goals in Elderly Patients with Hypertension：Evidence from Latest Clinical Studies [J]. Chinese General Practice, 2022, 25(11): 1305-1308.

刘凯旋,郭艺芳. 从最新临床研究证据看老年高血压患者的血压控制目标[J]. 中国全科医学, 2022, 25(11): 1305-1308. DOI: 10.12114/j.issn.1007-9572.2022.01.303.

References 13

[1]	李苏宁，陈祚，王增武，等. 我国老年人高血压现状分析[J]. 中华高血压杂志，2019，27（2）：140-148. DOI：10.16439/j.cnki.1673-7245.2019.02.010.
[2]	中国高血压防治指南修订委员会，高血压联盟（中国），中华医学会心血管病学分会，等. 中国高血压防治指南（2018年修订版）[J]. 中国心血管杂志，2019，24（1）：24-56. DOI：10.3969/j.issn.1007-5410.2019.01.002.
[3]	WHELTON P K，CAREY R M，ARONOW W S，et al. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention，detection，evaluation，and management of high blood pressure in adults：a report of the American College of Cardiology/American Heart Association Task Force on clinical practice guidelines [J]. Journal of the American College of Cardiology，2018，71（19）：e127-248. DOI：10.1016/j.jacc.2017.11.006.
[4]	LEUNG A A，NERENBERG K，DASKALOPOULOU S S，et al. Hypertension Canada's 2016 Canadian hypertension education program guidelines for blood pressure measurement，diagnosis，assessment of risk，prevention，and treatment of hypertension[J]. Can J Cardiol，2016，32（5）：569-588. DOI：10.1016/j.cjca.2016.02.066.
[5]	VISSEREN F L J，MACH F，SMULDERS Y M，et al. 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice[J]. Eur Heart J，2021，42（34）：3227-3337. DOI：10.1093/eurheartj/ehab484.
[6]	Sprint Research Group，WRIGHT J T Jr，WILLIAMSON J D，et al. A randomized trial of intensive versus standard blood-pressure control[J]. N Engl J Med，2015，373（22）：2103-2116. DOI：10.1056/NEJMoa1511939.
[7]	Blood Pressure Lowering Treatment Trialists' Collaboration. Age-stratified and blood-pressure-stratified effects of blood-pressure-lowering pharmacotherapy for the prevention of cardiovascular disease and death：an individual participant-level data meta-analysis[J]. Lancet，2021，398（10305）：1053-1064.
[8]	ZHANG W L，ZHANG S Y，DENG Y，et al. Trial of intensive blood-pressure control in older patients with hypertension[J]. N Engl J Med，2021，385（14）：1268-1279. DOI：10.1056/NEJMoa2111437.
[9]	WILLIAMS B，MANCIA G，SPIERING W，et al. 2018 ESC/ESH guidelines for the management of arterial hypertension[J]. Eur Heart J，2018，39（33）：3021-3104.
[10]	ARVANITIS M，QI G H，BHATT D L，et al. Linear and nonlinear mendelian randomization analyses of the association between diastolic blood pressure and cardiovascular events：the J-curve revisited[J]. Circulation，2021，143（9）：895-906.
[11]	JURASCHEK S P，HU J R，CLUETT J L，et al. Effects of intensive blood pressure treatment on orthostatic hypotension：a systematic review and individual participant-based meta-analysis[J]. Ann Intern Med，2021，174（1）：58-68.
[12]	LIP S，TAN L E，JEEMON P，et al. Diastolic blood pressure J-curve phenomenon in a tertiary-care hypertension clinic[J]. Hypertension，2019，74（4）：767-775. DOI：10.1161/HYPERTENSIONAHA.119.12787.
[13]	CARDOSO C R L，SALLES G F. Associations between achieved ambulatory blood pressures and its changes with adverse outcomes in resistant hypertension：was there a J-curve for ambulatory blood pressures? [J]. Hypertension，2021，77（6）：1895-1905. DOI：10.1161/HYPERTENSIONAHA.121.17200.

[1]	ZHOU Xiaoya, WANG Weikai, LIU Qian, LI Jianhua, SUN Bo, WANG Yanxia. Study of the Interaction between Sleep Quality and Melatonin Receptor 1B Gene Polymorphism on Gestational Hypertension [J]. Chinese General Practice, 2026, 29(21): 2975-2981.
[2]	CHAI Zhihao, ZHANG Weisen, LUO Jiaoling, ZHU Feng, ZHU Tong, JIN Yali, PAN Jing, LU Yingjun, JIANG Chaoqiang. The Mediation Effect of Socioeconomic Status in Childhood Parental Literacy and Cognitive Function in Middle-aged and Older People: Based on Guangzhou Biobank Cohort Study [J]. Chinese General Practice, 2026, 29(21): 2959-2966.
[3]	LI Wenping, CHEN Jianhua, XU Jiapei, JIN Xue, PAN Zihan, CHI Chunhua. A Scoping Review on the Empowerment of Community Elderly Health Services by Digital-Intelligent Health Management Platforms [J]. Chinese General Practice, 2026, 29(21): 2938-2949.
[4]	LI Feng, HU Changhao, LUO Xu. Progress in the Study of Influencing Factors and Intervention Strategies of Mental Health in Elderly Patients with Multiple Chronic Conditions [J]. Chinese General Practice, 2026, 29(20): 2816-2828.
[5]	REYILAI· Maimaiti, ZHOU Yiran, WU Yun, LIU Zhencheng, LU Yaoqin, WU Haiyan. Association between Novel Obesity Indicators and Cardiovascular Disease Risk in Hypertensive Patients [J]. Chinese General Practice, 2026, 29(20): 2836-2845.
[6]	ZHANG Xiaojuan, LIU Yang, PENG Bo, YE Yuan, ZHU Kun. Study on the Prevention and Treatment of Hypertension and Diabetes Mellitus in Community Hospital [J]. Chinese General Practice, 2026, 29(19): 2614-2620.
[7]	PANG Shu, SUN ying, JIANG Chunyan. Comparison of the Effectiveness of Fried's Frailty Phenotype and the FRAIL Scale in Assessing Pre-frailty among Community-dwelling Older Adults Undergoing Health Examinations [J]. Chinese General Practice, 2026, 29(19): 2664-2670.
[8]	MIAO Jingjie, ZHANG Jinwen, WU Qianhao, HAN Peipei. Research Advances on the Effects of Intermittent Fasting on Cardiometabolic Diseases [J]. Chinese General Practice, 2026, 29(18): 2538-2545.
[9]	HEI Moran, MA Hui'e, XU Zecheng, YAN Shiyan, LI Ziyan, YANG Yi, JIN Jun, CHEN Zelin, GUO Yi, ZHAO Xue, ZHAO Tianyi. Comparison, Analysis and Considerations of Methods for Determining Clinical Questions in Domestic and International Clinical Practice Guideline Development Manuals [J]. Chinese General Practice, 2026, 29(18): 2554-2560.
[10]	FAN Meixiang, YAN Yunyun, HUANG Yanyan. Interpretation and Discussion of Guidelines for Preventive Activities in General Practice: Bladder Cancer [J]. Chinese General Practice, 2026, 29(18): 2450-2453.
[11]	LI Simin, ZHANG Tingting, WANG Kunbo, YANG Jianzhou, PING Weiwei. Effects of Exercise Dosage on Elderly Patients with Sarcopenia: a Meta-analysis [J]. Chinese General Practice, 2026, 29(17): 2400-2409.
[12]	WANG Yibo, HE Kaiyu, LIANG Guofen, YANG Zhenhua, ZHAO Tingxian, LIAO Biyi, ZHANG La, LIU Shiwei, GONG Xuezhong, LIU Xusheng, GU Yueyu, QIN Xindong, SU Guobin. Diagnosis and Management of Recurrent Urinary Tract Infections in Women: a Comparison and Interpretation Based on Existing Guidelines and Evidence [J]. Chinese General Practice, 2026, 29(17): 2387-2399.
[13]	CHEN Yan, SHEN Dequan, SHENG Renlei, CHANG Yujie, YANG Jiaqi, DING Jie, SUN Zhifang, WANG Dahui. Influencing Factors and Importance Ranking of the Utilization of Primary-level Traditional Chinese Medicine Preventive and Health Care Services for the Elderly [J]. Chinese General Practice, 2026, 29(16): 2182-2189.
[14]	YU Shan, CHE Yajie, SUBIYINUER· Maimaiti, GUO Kaiyang, FENG Xingxing, YAN Ping. A Comparative Study on the Current Situation and Influencing Factors of Subjective Cognitive Decline among Urban and Rural Elderly People in Xinjiang [J]. Chinese General Practice, 2026, 29(16): 2227-2233.
[15]	YANG Tingting, ZHENG Li, LIANG Daqiang, WU fan, YUAN Xianxian, WEI lai, HU Jin, WANG Junhua, WANG Ziyun. Association between Sleep Fragmentation and Arteriosclerosis among Population Aged 40-65 Years [J]. Chinese General Practice, 2026, 29(16): 2190-2197.

Blood Pressure Control Goals in Elderly Patients with Hypertension：Evidence from Latest Clinical Studies

从最新临床研究证据看老年高血压患者的血压控制目标

RichHTML

PDF

Knowledge

Abstract

Cite this article

share this article

References 13

Related Articles 15

Recommended Articles

Metrics

Comments