Latest Developments in the Effect of Meal Sequence on Postprandial Blood Glucose in Diabetic Patients and Its Possible Mechanism

doi:10.12114/j.issn.1007-9572.2021.00.476

Abstract

Abstract: Postprandial hyperglycemia is a condition where a person has elevated blood glucose （higher than 7.8 mmol/L） 1-2 hours after eating a meal，which is a major contributor to elevated glycosylated hemoglobin，and is related to the occurrence and development of chronic diabetic complications. Therefore，postprandial glycemic control is a key facilitator to reaching the target glycosylated hemoglobin，and preventing and treating chronic diabetic complications. It has been found recently that changing the eating order，a dietary treatment，has notable effect on controlling the postprandial blood glucose of diabetic patients. We reviewed the concept and latest developments in the effect of meal sequence on postprandial blood glucose of diabetics and the potential mechanism，offering evidence for further research.

Key words: Diabetes mellitus, Meal sequence, Postprandial blood glucose, Glycosylated hemoglobin, Review

摘要： 餐后高血糖是指进餐后1~2 h的餐后血糖高于7.8 mmol/L，餐后高血糖是导致糖化血红蛋白升高的主要原因，且其与糖尿病慢性并发症的发生发展具有相关性，控制餐后血糖是促进糖化血红蛋白达标、防治糖尿病慢性并发症的重要措施。近年研究发现，改变进餐顺序的饮食治疗方法可以显著改善糖尿病患者的餐后血糖。本文就进餐顺序的概述、进餐顺序对糖尿病患者餐后血糖的研究现状及其可能机制做如下综述，旨在为进一步的研究提供借鉴。

关键词: 糖尿病, 进餐顺序, 餐后血糖, 糖化血红蛋白, 综述

DING Shaoyu,JU Changping,YANG Bingquan, et al. Latest Developments in the Effect of Meal Sequence on Postprandial Blood Glucose in Diabetic Patients and Its Possible Mechanism　[J]. Chinese General Practice, 2021, 24(27): 3517-3521. DOI: 10.12114/j.issn.1007-9572.2021.00.476.
丁少玉,鞠昌萍,杨兵全等. 进餐顺序对糖尿病患者餐后血糖的作用及可能机制的研究进展[J]. 中国全科医学, 2021, 24(27): 3517-3521. DOI: 10.12114/j.issn.1007-9572.2021.00.476.

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