Effects of Sensory Integration Training on Early Intervention for Critically Ill Preterm Infants

doi:10.12114/j.issn.1007-9572.2018.00.062

Abstract

Abstract: Objective　To study the effects of sensory integration training on early intervention for high-risk preterm infants.Methods　For intervention，we selected 102 preterm infants who were critically ill as a result of brain damage and other high risk factors and were treated in the Department of Rehabilitation Medicine of the West China Second University Hospital of Sichuan University between January 2015 and May 2016.The observation group and control group were subjected to neurodevelopment therapy training，and the observation group received additional home-based sensory integration training，including visual training，auditory stimulation，tactile training，vestibular function training，kinesthetic stimulus，and other training，for a total intervention time of 12 months.In the 3rd，6th and 12th months after the intervention，we used the Test of Sensory Functions in Infants （TSFI） to evaluate the sensory development level and used the Bayley Scales of Infant Development to evaluate the Mental Development Index （MDI） and Psychomotor Development Index （PDI）．Results　Rehabilitation therapy and time both had an interaction effect on the level of sensory development （P<0.001），and the main effects were both significant （P=0.049，P<0.001）．The TSFI scores of the observation group at the 3rd，6th and 12th months were all higher than those of the control group （P<0.05）．Rehabilitation therapy and time both had an interaction effect on the MDI （P=0.030），and the main effects were both significant （P=0.049，P<0.001，respectively）．Neither rehabilitation therapy nor time had an interaction effect on the PDI（P=0.151），and the main effects were both significant （P=0.008，P<0.001，respectively）．Conclusion　Sensory integration therapy can improve sensory，motor，and cognitive functions in critically ill preterm
infants.

Key words: Infant, premature, diseases；Sensory integration training；Early medical intervention；Motor；Intelligence

摘要：

目的　探讨感觉统合训练在高危早产儿早期干预中的应用价值，为临床早期干预提供一定依据。方法　选取2015年1月—2016年5月因脑损伤等高危因素在四川大学华西第二医院康复医学科进行干预的102例高危早产儿为研究对象。采用随机数字表法，将患儿分为对照组（50例）和观察组（52例）。两组患儿均接受神经发育疗法（NDT）训练，观察组在上述治疗方案基础上增加居家感觉统合训练内容，包括视觉训练、听力刺激、触觉训练、前庭功能训练、运动觉刺激等，总干预时间为12个月。分别在干预后3、6、12个月时，采用婴幼儿感觉功能评估量表（TSFI）评估患儿感觉发育水平，采用贝利婴幼儿发展量表（BSID）测定患儿认知发育指数（MDI）和精神运动发育指数（PDI）。结果　康复方法与时间对患儿感觉发育水平存在交互作用（P<0.001）；康复方法与时间对患儿感觉发育水平主效应均显著（P=0.049、P<0.001）；其中观察组在3、6、12个月时TSFI评分均高于对照组（P<0.05）。康复方法与时间对患儿MDI存在交互作用（P=0.030），康复方法与时间对患儿MDI主效应均显著（P=0.049、P<0.001）。康复方法与时间对患儿PDI无交互作用（P=0.151），康复方法与时间对患儿PDI主效应均显著（P=0.008、P<0.001）。结论　感觉统合训练能提高高危早产儿感觉能力及运动和认知功能。

关键词: 婴儿, 早产, 疾病, 感觉统合训练, 早期医疗干预, 运动, 智力

MA Dan,LI Na,WANG Qiu, et al. Effects of Sensory Integration Training on Early Intervention for Critically Ill Preterm Infants[J]. Chinese General Practice, 2018, 21(32): 4028-4031. DOI: 10.12114/j.issn.1007-9572.2018.00.062.
马丹,李娜,王秋等. 感觉统合训练在高危早产儿早期干预中的疗效分析研究[J]. 中国全科医学, 2018, 21(32): 4028-4031. DOI: 10.12114/j.issn.1007-9572.2018.00.062.

References

［1］顾瓅，仲越，李双双，等．新生儿重症监护病房的早期干预在极低出生体重儿中的应用［J］．中国儿童保健杂志，2017，25（2）：167-170.4030
GU L，ZHONG Y，LI S S，et al．Application of early intervention in very low birth weight infants treated in neonatal intensive care unit［J］．Chinese Journal of Child Health Care，2017，25（2）：167-170.4030
［2］王章星，童燕梅，陈明秋.早期干预随访对高危儿发育影响的临床研究［J］．中国中西医结合儿科学，2016，8（6）：560-563.DOI：10.3969/j.issn.16743865.2016.06.002.4030
WANG Z X，TONG Y M，CHEN M Q.Study on the effect of early intervention and follow-up on the development of high risk infants［J］．Chinese Pediatrics of Integrated Traditional and Western Medicine，2016，8（6）：560-563.DOI：10.3969/j.issn.16743865.2016.06.002.4030
［3］王培玲，魏秀红.感觉统合训练对轻度认知功能障碍患者认知功能的影响［J］．山东医药，2012，52（35）：48-50.DOI：10.3969/j.issn.1002-266X.2012.35.017.4030
WANG P L，WEI X H.Effect of sensory integration training on the cognition in patients with mild cognitive impairment［J］．Shandong Medical Journal，2012，52（35）：48-50.DOI：10.3969/j.issn.1002-266X.2012.35.017.4030
［4］邵肖梅，叶鸿瑁，丘小汕.实用新生儿学［M］．4版.北京：人民卫生出版社，2011：195.4030
SHAO X M，YE H M，QIU X S.Practice of Neonatology［M］．4th ed.Beijing：People's Medical Publishing House，2011：195.4030
［5］吴满红，常燕群，李奎，等．早期干预对早产儿运动和智力发育的影响［J］．中国康复理论与实践，2013，19（3）：261-262.DOI：10.3969/j.issn.1006-9771.2013.03.016.4030
WU M H，CHANG Y Q，LI K，et al．Effect of early intervention on motor and mental development of premature infants［J］．Chinese Journal of Rehabilitation Theory and Practice，2013，19（3）：261-262.DOI：10.3969/j.issn.1006-9771.2013.03.016.4031
［6］张亚男，陈伟，巩尊科，等．感觉统合训练对高危儿粗大运动功能发育的影响［J］．中国康复，2017，32（5）：355-357.DOI：10.3870/zgkf.2017.05.001.4031
ZHANG Y N，CHEN W，GONG Z K，et al．Effects of sensory integration training on gross motor development of high risk infants［J］．Chinese Journal of Rehabilitation，2017，32（5）：355-357.DOI：10.3870/zgkf.2017.05.001.4031
［7］方素珍，石坚，李宏，等．感觉统合训练在缺氧缺血性脑病患儿早期干预中的疗效观察［J］．中华神经医学杂志，2006，5（8）：845-847.DOI：10.3760/cma.j.issn.1671-8925.2006.08.028.4031
FANG S Z，SHI J，LI H，et al．Clinical effects of sensory integrative therapy in the early intervention of infants with hypoxic-ischemic encephalopathy［J］．Chinese Journal of Neuromedicine，2006，5（8）：845-847.DOI：10.3760/cma.j.issn.1671-8925.2006.08.028.4031
［8］任宁，梁政波，夏玮，等．贝利婴幼儿发展量表的临床应用进展［J］．护理学杂志，2017，32（15）：99-102.DOI：10.3870/j.issn.1001-4152.2017.15.099.4031
REN N，LIANG Z B，XIA W，et al．Clinical application of Bayley scales of infant and toddler development：a literature review［J］．Journal of Nursing Science，2017，32（15）：99-102.DOI：10.3870/j.issn.1001-4152.2017.15.099.4031
［9］刘静，张鸾，王二艳，等．高危早产儿早期行神经发育干预改善运动和认知发育的作用［J］．昆明医科大学学报，2016，37（3）：81-84.DOI：10.3969/j.issn.1003-4706.2016.03.020.4031
LIU J，ZHANG L，WANG E Y，et al．Effect of early intervention in neurodevelopment on motor and cognitive development of high risk premature infants［J］．Journal of Kunming Medical University，2016，37（3）：81-84.DOI：10.3969/j.issn.1003-4706.2016.03.020.4031
［10］HAYASHIDA K，NAKATSUKA M.Promoting factors of physical and mental development in early infancy：a comparison of preterm delivery/low birth weight infants and term infants［J］．Environ Health Prev Med，2014，19（2）：160-171.DOI：10.1007/s12199-013-0370-6.4031
［11］CABRAL T I，PEREIRA DA SILVA L G，TUDELLA E，et al．Motor development and sensory processing：a comparative study between preterm and term infants［J］．Res Dev Disabil，2014（36）：102-107.DOI：10.1016/j.ridd.2014.09.018.4031
［12］ZIVIANI J，DARLINGTON Y，FEENEY R，et al．Early intervention services of children with physical disabilities：complexity of child and family needs［J］．Aust Occup Ther J，2014，61（2）：67-75.DOI：10.1111/1440-1630.12059.4031
［13］PEK?ETIN S，AKI E，üSTUNYURT Z，et al．The efficiency of sensory integration interventions in preterm infants［J］．Percept Mot Skills，2016，123（2）：411-423.DOI：10.1177/0031512516662895.4031
［14］BR?RING T，OOSTROM K J，LAFEBER H N，et al．Sensory modulation in preterm children：theoretical perspective and systematic review［J］．PLoS One，2017，12（2）：e0170828.DOI：10.1371/journal.pone.0170828.4031
［15］NWABARA O，ROGERS C，INDER T，et al．Early therapy services following neonatal intensive care unit discharge［J］．Phys Occup Ther Pediatr，2017，37（4）：414-424.DOI：10.1080/01942638.2016.1247937.4031

[1]	DU Qiongliang, LIN Bailang, GUO Honghua. Research Progress and Implications of Group Well-child Care [J]. Chinese General Practice, 2025, 28(21): 2672-2678.
[2]	ZHANG Wenjie, LI Jun, CHEN Hengwen, TAN Yuqing, XIE Zicong, WU Ji, MENG Chao, LI Zhaoling, ZHANG Lesong. Collection and Determination of Clinical Problems and Outcome Indicators of Expert Consensus on Clinical Application of Ethnic Medicine in the Treatment of Palpitation (Arrhythmia-premature Ventricular Complexes) [J]. Chinese General Practice, 2025, 28(04): 407-412.
[3]	MA Xiaoxia, SHI Jishun, NIU Lihua, CHEN Ningqing, DING Yan. A Qualitative Study on the Status of Maternal and Infant Health Services in Shanghai Communities under the New Situation [J]. Chinese General Practice, 2024, 27(28): 3529-3534.
[4]	LOU Wubin, LI Fang, ZHANG Weixing, SHEN Jie. The Value of High Frequency Oscillatory Ventilation Combined with Volume Guarantee in Extremely Preterm Infants with Respiratory Distress Syndrome [J]. Chinese General Practice, 2024, 27(13): 1616-1622.
[5]	ZHANG Shengnan, XU Shihua, HUANG Rongchao, CHEN Jian, ZHAO Chunru, MENG Minglyu, MA Yingjiao. Trend and Forecast Analysis of Premature Mortality Probability by Four Major Non-communicable Diseases in Baise from 2015 to 2021 [J]. Chinese General Practice, 2024, 27(11): 1387-1394.
[6]	LIU Weina, GE Haiyan, MA Jing, CAO Qinying, BAI Xingyu, CUI Shifang, QIAO Yanxia. A Study on the Relationship of Vitamin A and E Levels in Umbilical Cord Blood with Respiratory Distress Syndrome in Preterm Infants [J]. Chinese General Practice, 2023, 26(33): 4152-4158.
[7]	CHE Guoyu, MA Aqin, YANG Lan, LI Jing, WANG Ling. Influence of Group Cognitive Behavioral Therapy on Pregnancy Outcomes among Pregnant Women with Gestational Diabetes Mellitus: a Propensity Score Matching Study [J]. Chinese General Practice, 2023, 26(24): 2968-2972.
[8]	TANG Binzhi, YANG Qian, LING Qiying, LI Maojun, SHI Wei, WU Qing. Early Postnatal Management of an Extremely Low Birth Weight Periviable Infant [J]. Chinese General Practice, 2023, 26(20): 2559-2566.
[9]	YU Zhumei, LIU Annuo, XIAO Juan, TANG Yuxia, YU Li, TONG Huanhuan. Risk Factors for Bronchopulmonary Dysplasia in Premature Infants: a Meta-analysis [J]. Chinese General Practice, 2023, 26(03): 356-366.
[10]	LAN Hailong, NING Guanyuan, HUANG Xiangmin, XIAO Yeyu. Sequences of SS_TSE and Modified Abdominal T2WI Magnetic Resonance Imaging in the Diagnosis of Neonatal Pneumonia [J]. Chinese General Practice, 2023, 26(03): 308-312.
[11]	TENG Xiaoyun, LIANG Jie, TAN Jilei, SUN Jianfeng, LIANG Hua, QIN Shanshan, LU Caina, WEI Qin. A Randomized Controlled Study of Multisensory Interventions in Promoting Brain Function Development in Premature Infants [J]. Chinese General Practice, 2023, 26(02): 168-174.
[12]	SHEN Qiao, TANG Yuman, LENG Hongyao, LEI Ruobing, ZHENG Xianlan. Psychometric Properties of the Pain Assessment Scales in Newborns: an Overview of Systematic Review [J]. Chinese General Practice, 2022, 25(35): 4453-4461.
[13]	LIAO Jia, WEI Shuangyi, LIU Gang. Overview and Trends of Premature Deaths Due to Four Major Noncommunicable Diseases among Shenzhen Permanent Residents, 2014-2020 [J]. Chinese General Practice, 2022, 25(32): 4085-4090.
[14]	Xue XIAO, Yuqi WANG, Xiaolan LAI, Shaotao ZHONG, Cuiliu ZHAO, Dan LIU, Lin LI, Rongshao TAN, Hongling YANG. Effect of Maternal Intestinal Floras on Neonatal Birth Weight [J]. Chinese General Practice, 2022, 25(19): 2363-2370.
[15]	Zhenzhen JUE, Juan SONG, Xiangmin ZHANG, Han ZHANG, Huimin DONG, Wendong LI, Falin XU. Risk Factors for Adverse Neurodevelopment Outcomes in Neonates with Necrotizing Enterocolitis [J]. Chinese General Practice, 2022, 25(18): 2275-2279.