Abstract:

Objective　To investigate the effect of individualized constant power exercise on pulse wave in patients with chronic diseases.Methods　Eleven patients with chronic diseases（blood sugar，blood lipids，and blood pressure abnormalities） managed by our team were enrolled as the patient group in the Beijing Rehabilitation Hospital affiliated to Capital Medical University in June 2017 and eight normal persons were enrolled in the Fuwai Hospital，Chinese Academy of Medical Sciences as the normal group during the same period.The individualized quantitative exercise prescription was developed by cardiopulmonary exercise test，and the radial artery pulse wave was measured before and at 5，15，30，40 min after exercise，with 30 minutes of exercise every day.The original data of pulse wave of subjects was plotted with Origin，and the waveform characteristics of the rise，fall，notch or plateau of the radial artery pulse wave and its changes before and after the exercise were qualitatively analyzed，and the pre- and post-existing notch occurrence rates were compared in two groups.Results　The notch occurrence rate of the patient was lower than that of normal group（P=0.010） before exercise.After exercise，the pulse wave waveform of both groups became higher and narrower.There was no statistical significance in notch occurrence rate of patient group before and after 5 min，15 min，30 min，40 min of exercise（P>0.05）．There was no significant difference in the notch occurrence rate between the patient group and the normal group after 5 min，15 min ，30 min，40 min of exercise（P>0.05）．Conclusion　Individualized constant power exercise can change the pulse wave waveform，which may be an effective indicator for exercise control of chronic diseases and hypertension，but its mechanism needs further study.

Key words: Exercise therapy, Cardiopulmonary exercise testing, Pulse, Chronic disease, Hypertension, Diabetes mellitus, Hyperlipidemia

摘要： 目的　探讨个体化精准恒定功率运动对慢性病患者脉搏波波形特征的影响。方法　选取2017年6月在首都医科大学附属北京康复医院接受本团队管理的慢性病（以血糖、血脂、血压异常为主）患者中的11例为慢病组，同期选取在中国医学科学院阜外医院学习的正常人8例为正常组。以心肺运动试验评估制定个体化精准恒定功率运动处方，每天运动30 min，在运动前和运动后5、15、30、40 min测量其桡动脉脉搏波波形。对受试者脉搏波原始数据用Origin作图，对桡动脉脉搏波的上升、下降、切迹或平台等波形特征及其运动前后变化进行定性分析，并比较两组运动前、后切迹出现率。结果　运动前慢病组切迹出现率低于正常组（P=0.010）。运动后两组脉搏波均较运动前的波峰变高、波形变窄。运动后5 、15、30、40 min慢病组切迹出现率同运动前比较，差异无统计学意义（P>0.05），正常人切迹出现率始终为100.0%；运动后5、15、30 、40 min慢病组切迹出现率与正常组比较，差异无统计学意义（P>0.05）。结论　个体化精准恒定功率运动可改变脉搏波波形，其可能作为运动疗法有效管控慢性病的指标，其机制有待进一步研究。

关键词: 运动疗法, 心肺运动试验, 脉搏, 慢性病, 高血压, 糖尿病, 高脂血症