Abstract: Vitamin D is well known as an important regulator of bone metabolism.Studies show that vitamin D also involves in the occurrence and development of cardiovascular disease，immune system disease，tumor，metabolic disease and neurological disease.Compared with populations with normal vitamin D，those with vitamin D deficiency are more likely to suffer from the aforementioned diseases.As evidence demonstrates that vitamin D supplementation is beneficial to the prevent and to the improvement of the outcome of these diseases，vitamin D supplementation therapy could be used as a promising regimen.

Key words: Vitamin D, Non-skeletal diseases, New recognition

摘要： 维生素D在骨代谢中的重要作用已被广泛认知。近年来发现维生素D还参与了心血管系统疾病、免疫系统疾病、肿瘤、代谢性疾病、神经系统疾病的发生发展过程，相对于维生素D水平正常的人群，维生素D缺乏者更易罹患此类疾病，一些研究发现补充维生素D对预防此类疾病的发生及疾病预后有益，提示维生素D补充疗法可能成为治疗这些疾病的新方向。

关键词: 维生素D, 骨外系统疾病, 新认识