Exercise capacity is a strong predictive factor of mortality in hemodialysis patients. Hence, it is urgently needed to explore convenient and effective assessment tools to evaluate exercise capacity.

To validate the Duke Activity Status Index (DASI) and General Practice Physical Activity Questionnaire (GPPAQ) walking pace question in Chinese and British hemodialysis patients.

From January 2018 to September 2020, 40 hemodialysis patients from a Chinese tertiary hospital and 39 patients from Leicester Renal Network in the United Kingdom were assessed exercise capacity and walking speed using DASI and GPPAQ walking pace question, respectively. Meanwhile, the shuttle walking test (SWT) and gait speed test in short physical performance battery (SPPB) were conducted with the two cultural groups to validate the DASI and the GPPAQ walking pace question. The validity of DASI was tested by correlation analysis, and the validity test of GPPAQ pace problem was by analysis of variance, respectively.

There was a positive correlation between DASI and the incremental shuttle walking test (ISWT) in hemodialysis patients in China and the United Kingdom (r_China=0.39, r_sUK=0.60; P<0.05) , but no correlation with the endurance shuttle walking test (ESWT) (P>0.05) . According to the self-assessment results of the pace problem in the GPPAQ, Chinese hemodialysis patients were classified into four categories: slow pace, steady pace, brisk pace, and fast pace, the objectively measured SPPB pace range of the 4 types of patients overlapped, and there was no significant difference in the average SPPB pace (P>0.05) . British hemodialysis patients were classified into three categories: slow pace, steady pace, and brisk pace, there was a statistically significant difference in the average SPPB pace measured objectively among the three types of patients (P<0.05) . Among them, the average SPPB pace of self-assessed slow pace patients was lower than that of self-assessed steady pace and brisk pace (P<0.05) .

DASI can effectively measure the exercise capacity of hemodialysis patients in China and the United Kingdom. In the two cultural groups, GPPAQ walking pace question could not assist patients inaccurately assessing their gait speed. However, it has potential utility for distinguishing between "slow" and "not slow" gait speed.

运动能力是血液透析患者强有力的死亡预测因子。因此，寻求便捷且有效的评价工具以实现患者运动能力的评估是目前迫切需要探讨的问题。

在中国与英国血液透析患者中对杜克活动状况指数（DASI）与日常体力活动问卷（GPPAQ）中的步速问题进行效度检验。

于2018年1月至2020年9月，选取中国某大学附属医院血液透析患者40例与英国莱斯特肾脏病网络系统血液透析患者39例。采用DASI和GPPAQ的步速问题评估患者的运动能力与步速，同时采用往返行走试验（SWT）与简易机体功能评估（SPPB）的步速测试对患者进行测试验证。DASI的效度检验采用相关性分析，GPPAQ步速问题的效度检验采用方差分析。

中国与英国血液透析患者的DASI和递增负荷往返行走试验（ISWT）呈正相关（r_中国=0.39，r_s英国=0.60；P<0.05），和耐力往返步行试验（ESWT）无相关关系（P>0.05）。根据GPPAQ中步速问题的自我评估结果，将中国血液透析患者归为慢速、平稳步速、轻盈步速、快速4类，4类患者客观测量的SPPB步速范围存在重叠，平均SPPB步速比较，差异无统计学意义（P>0.05）；将英国血液透析患者归为慢速、平稳步速、轻盈步速3类，3类患者客观测量的平均SPPB步速比较，差异有统计学意义（P<0.05），其中自我评估为慢速患者的平均SPPB步速低于自我评估为平稳步速、轻盈步速者（P<0.05）。

DASI可以有效测量中国与英国血液透析患者的运动能力。在两个不同文化群体中，GPPAQ的步速问题均无法协助患者准确报告自身步速，但在区分"慢"与"不慢"的步速上具有一定潜在效用。