Chinese General Practice ›› 2022, Vol. 25 ›› Issue (11): 1314-1319.DOI: 10.12114/j.issn.1007-9572.2021.01.502

Special Issue: 患者报告结局最新文章合集

• Clinical Decision Support • Previous Articles     Next Articles

Research Status and Thinking of Minimal Clinically Important Difference in Patient-reported Outcome Assessment Tool for Allergic Rhinitis

  

  1. 1.Henan University of Traditional Chinese MedicineZhengzhou 450046China

    2.First Affiliated Hospital of Henan University of Chinese MedicineZhengzhou 450099China

    *Corresponding authorXIE YangAssociate chief physicianDoctoral supervisorE-mailxieyanghn@163.com

  • Received:2021-08-27 Revised:2021-12-15 Published:2022-04-15 Online:2022-03-28

变应性鼻炎患者报告结局测评工具最小临床重要差值的研究现状与思考

  

  1. 1450046 河南省郑州市,河南中医药大学
    2450000 河南省郑州市,河南中医药大学第一附属医院
  • 通讯作者: 谢洋
  • 基金资助:
    国家自然科学基金资助项目(81674098);中原千人计划(ZYQR201810159);河南省高校科技创新人才支持计划(19HASTIT008);中华中医药学会青年人才托举工程项目(2019-QNRC2-B02)

Abstract:

As the patient-reported outcome (PRO) assessment tool has been increasingly used in the clinical efficacy evaluation of patients with allergic rhinitis (AR) , the judgment and interpretation of changes in measurement results of assessment tools have become increasingly important. For the judgment of clinical research results, not only the statistical differences, but also the minimum clinically important difference (MCID) must be paid attention to. This paper systematically sorts out the MCID of the AR-PRO assessment tool, in order to provide a reference for AR-related clinical diagnosis and treatment decision-making and the objectification of the PRO assessment tool.

Key words: Rhinitis, Minimal clinically important difference, Minimal clinically important difference, Patient reported outcome, Clinical decision-making

摘要:

随着患者报告结局(PRO)测评工具越来越多地被应用于变应性鼻炎(AR)患者的临床疗效评价,测评工具测评结果变化的判定和解释变得日益重要,而对于临床研究结果的判断,不仅要关注其统计学差异,更要关注其最小临床重要差值(MCID)。本文系统梳理了变应性鼻炎患者报告结局(AR-PRO)测评工具的MCID,以期为AR相关临床诊疗决策和PRO测评工具客观化提供参考依据。

关键词: 鼻炎, 最小临床意义变化值, 最小临床重要差值, 患者报告结局, 临床决策

CLC Number: