Abstract: Background　Chronic Obstructive Pulmonary Disease（COPD）is characterized by its progressive and irreversible nature，prolonged disease course and frequent exacerbations. Patients often manifest psychological issues such as anxiety and depression，which significantly impair their quality of life. Quality of life scales represent the most prevalent method for assessing treatment outcomes and quality of life in COPD patients. Numerous COPD-specific quality of life scales have been developed both domestically and internationally. However，considerable variations exist across different scales in terms of their dimensions，items，and measurement levels. Consequently，comparative analysis among these diverse scales is essential for their appropriate application. Objective　To conduct a scoping review of disease-specific quality of life measurement tools for patients with chronic obstructive pulmonary disease. Methods　We systematically searched seven databases，including Web of Science，PubMed，Embase，CNKI，Wanfang Database，VIP Database，and China Biomedical Literature Database，using keywords related to "chronic obstructive pulmonary disease" "quality of life" and "measurement properties." The search timeline spanned from the inception of these databases to December 31，2023. We extracted information on the characteristics of each tool from the original development literature，and organized the dimensions addressed by these tools along with a comprehensive overview of their measurement properties. Results　Our review encompassed 25 COPD-specific quality of life measurement tools，with 7 developed with a focus on the Chinese population and 18 originating from abroad. Notably，7 of the foreign-developed scales have received extensive validation within Chinese population. Respiratory symptoms（including shortness of breath，coughing，expectoration，chest tightness and wheezing），social interaction，and the impact on daily life were found to be the most frequently measured dimensions across these scales，with an occurrence in 92.0% of the scales. The majority of the scales utilized Cronbach's α to assess internal consistency. In terms of scale validity assessment，Chinese-developed scales predominantly emphasized content and construct validity，while foreign-developed scales validated domestically were used more frequently for criterion validity. Responsiveness/sensitivity and the minimum clinically important difference（MCID）were relatively infrequently determined. Conclusion　Despite a multitude of studies on the development and validation of COPD-specific quality of life measurement tools，there is a discernible absence of guidance from modern measurement theories. The interest of Chinese researchers in these COPD-specific quality of life measurement tools has increased in recent years. Going forward，it is recommended to employ contemporary measurement methodologies，such as item response theory，for the development and validation of such scales. Additionally，the utilization of the COSMIN guidelines is advocated for a systematic assessment of the measurement properties of these scales.

Key words: Pulmonary disease, chronic obstructive；Quality of life；Disease-specific measurement tool；Questionnaire；Review

摘要： 背景　慢性阻塞性肺疾病（以下简称慢阻肺病）具有进行性和不可逆性，病程长且反复发作，患者常表现出焦虑/抑郁等心理问题，严重影响患者的生命质量，生命质量量表是测量慢阻肺病患者治疗效果和生命质量最常用的方式，国内外研制了多个慢阻肺病特异性生命质量量表，但不同量表之间的维度、条目和水平差异较大，在应用时需要对不同量表进行对比和分析。目的　对慢阻肺病患者特异性生命质量测量工具进行范围综述。方法　以“慢性阻塞性肺疾病”“生命质量”“心理测量学特性”“chronic obstructive pulmonary disease”“quality oflife”“measurement properties”等为检索词，系统检索 Web of Science、PubMed、Embase、中国知网、万方数据知识服务平台、维普网和中国生物医学文献服务系统共7个数据库，检索时限为建库至 2023-12-31。提取工具原始开发文献的基本特征，对工具涵盖维度以及测量性能指标总体情况进行梳理与汇总。结果　共纳入25个慢阻肺病特异性生命质量测量工具，其中7个为基于中国人群开发量表，18个为国外量表，在国外量表中，共有7个量表在中国人群中得到广泛验证。在各维度中，呼吸道症状（包括呼吸困难、咳嗽、咳痰、胸闷和喘息）、社会交往以及日常生活影响这三个维度的测量频次最高，达到 23 个（92.0%）。在量表信度测评中，主要使用Cronbach'sα系数来评估内部一致性；在量表效度测评中，国内开发和验证的量表主要侧重于内容效度和构念效度，国内验证的国外量表其效标效度的使用频次更高；反应度/灵敏度和最小临床重要差值（MCID）的使用频率均较低。结论　慢阻肺病特异性生命质量测量工具开发或验证研究数量繁多，但缺乏现代测量理论的指导。近些年我国学者对慢阻肺病特异性生命质量测量工具的关注逐渐增多，未来应采取项目反应理论等现代测量方法学进行量表开发或验证，使用国际COSMIN指南对量表测量性能指标进行系统评价。

关键词: 肺疾病, 慢性阻塞性；生命质量；特异性测量工具；量表；综述