Abstract: Background　Bronchial asthma is a common respiratory disease，with its incidence increasing yearly and a high disease burden. High-quality clinical practice guidelines and expert consensus can help physicians make more scientific decisions in diagnosis and treatment，improve clinical efficacy，and reduce the waste of resources. The selection and development of high-quality guidance documents are of great significance to the treatment of asthma. Objective　In order to provide a basis and reference for further improvement，as well as updating and developing the higher-quality guidelines，we systematically evaluated the methodological quality of asthmatic guidelines/expert consensus published in China. Methods　We searched the asthmatic guidelines/consensus from CNKI，Wanfang，VIP database，and Full-Text Database of Chinese Medical Journal. The time limitation was from January 1，2013 to October 20，2023. The AGREE-China tool was used to evaluate the quality of the guidelines/consensus，summarize and analyze the main recommendations of the included guidelines/consensus. Results　Fifteen guidelines/consensuses were finally included. Average scores of each domain of AGREE-China were as follows. "Scientific validity/rigor" was 33.98%，" validity/safety" was 38.00%，"economy" was 20.00%，"usability/feasibility" was 73.71%，and "conflict of interest" was 84.00%. The overall quality of 5 guidelines were relatively good. The main recommendations had 3 areas，including diagnosis，treatment（drug therapy and non-drug therapy），as well as health education and management. Conclusion　The overall quality of domestic asthmatic guidelines is general. The methodological quality is improving constantly，but further improvement is still needed in the areas of science/rigor and economy.

Key words: Asthma, Guidebook, Expert consensus, Systematic reviews as topic, AGREE-China

摘要： 背景　支气管哮喘是常见的呼吸系统疾病，其发病率逐年上升，疾病负担重。高质量的临床实践指南和专家共识可以帮助医生在诊疗中做出更为科学的决策，提高临床疗效，减少资源浪费。遴选和制订高质量指导性文件对哮喘的治疗具有重要意义。目的　系统评价国内发布的哮喘指南 / 专家共识的方法学质量，为进一步完善、更新和制订更高质量指南提供依据和借鉴。方法　检索中国知网、万方数据知识服务平台、维普网、中华医学期刊全文数据库收录的相关哮喘指南 / 共识，检索时限从 2013-01-01—2023-10-20。采用 AGREE-China 工具对指南 / 共识质量进行评价，并对较高质量的 5 部指南 / 共识的主要推荐意见进行总结分析。结果　最终纳入指南 / 共识 15 部。AGREE-China 各领域中平均得分：“科学性 / 严谨性”33.98%，“有效性 / 安全性”38.00%，“经济性”20.00%，“可用性 / 可行性”73.71%，“利益冲突”84.00%。整体质量较好的有 5 部指南，主要推荐意见包括诊断、治疗（药物治疗和非药物治疗）以及健康教育和管理 3 个方面。结论　国内哮喘指南的总体质量一般，方法学质量不断提高，但在科学性 / 严谨性、经济性领域仍有待进一步改进。

关键词: 哮喘, 指南, 专家共识, 系统评价, AGREE-China