Chinese General Practice ›› 2024, Vol. 27 ›› Issue (02): 150-155.DOI: 10.12114/j.issn.1007-9572.2023.0507
Special Issue: 乳腺癌最新文章合集; 女性健康最新文章合集; 肥胖最新文章合集
• Original Research • Previous Articles Next Articles
Received:
2023-06-13
Revised:
2023-08-20
Published:
2024-01-15
Online:
2023-10-23
Contact:
ZHANG Qingsong
通讯作者:
张青松
作者简介:
基金资助:
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URL: https://www.chinagp.net/EN/10.12114/j.issn.1007-9572.2023.0507
组别 | 例数 | 年龄(岁) | BMI(kg/m2) | 空腹血糖(mmol/L) | 收缩压(mmHg) | 舒张压(mmHg) | HDL-C(mmol/L) | 三酰甘油[M(P25,P75),mmol/L] | 腰围(cm) |
---|---|---|---|---|---|---|---|---|---|
MHNW组 | 12 739 | 45.4±11.7 | 22.0±1.9 | 5.01±1.09 | 117±18 | 76±10 | 1.58±0.42 | 0.96(0.68,1.34) | 77.52±9.02 |
MUNW组 | 1 060 | 57.4±9.9 | 23.2±1.5 | 6.83±2.92 | 141±19 | 85±10 | 1.52±0.48 | 2.15(1.69,2.99) | 87.84±8.54 |
MHO组 | 6 394 | 49.1±10.3 | 27.8±2.6 | 5.11±1.08 | 125±20 | 81±11 | 1.56±0.37 | 1.19(0.90,1.56) | 86.95±9.12 |
MUO组 | 3 213 | 55.9±9.1 | 28.9±2.9 | 6.51±2.58 | 144±20 | 88±11 | 1.54±0.47 | 2.12(1.70,2.91) | 93.65±8.38 |
检验统计量值 | 1 089.49 | 13 577.90 | 1 247.89 | 2 221.82 | 1 463.69 | 17.38 | 5 899.87a | 3 630.85 | |
P值 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | |
组别 | 总胆固醇(mmol/L) | 受教育程度[名(%)] | 糖尿病[名(%)] | 高血压[名(%)] | 服用调脂药[名(%)] | 吸烟[名(%)] | 饮酒[名(%)] | 体育锻炼[名(%)] | |
高中以下 | 高中及以上 | ||||||||
MHNW组 | 4.82±1.01 | 8 048(63.18) | 4 691(36.82) | 340(2.67) | 2 196(17.24) | 53(0.42) | 253(1.99) | 1 035(8.12) | 1461(11.47) |
MUNW组 | 5.29±1.31 | 843(79.53) | 217(20.47) | 372(35.09) | 740(69.81) | 49(4.52) | 37(3.49) | 37(3.49) | 207(19.53) |
MHO组 | 4.97±1.26 | 4 745(74.21) | 1 649(25.79) | 206(3.22) | 1 965(30.73) | 30(0.47) | 166(2.60) | 430(6.73) | 881(13.78) |
MUO组 | 5.34±1.30 | 2 584(80.42) | 629(19.58) | 978(30.44) | 2 509(78.09) | 134(4.17) | 162(5.04) | 151(4.70) | 654(20.35) |
检验统计量值 | 219.34 | 535.98b | 3 900.55b | 5 141.44b | 462.10b | 96.34b | 70.94b | 204.67b | |
P值 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
Table 1 Comparison of basic characteristics of population with different metabolic obesity phenotypes
组别 | 例数 | 年龄(岁) | BMI(kg/m2) | 空腹血糖(mmol/L) | 收缩压(mmHg) | 舒张压(mmHg) | HDL-C(mmol/L) | 三酰甘油[M(P25,P75),mmol/L] | 腰围(cm) |
---|---|---|---|---|---|---|---|---|---|
MHNW组 | 12 739 | 45.4±11.7 | 22.0±1.9 | 5.01±1.09 | 117±18 | 76±10 | 1.58±0.42 | 0.96(0.68,1.34) | 77.52±9.02 |
MUNW组 | 1 060 | 57.4±9.9 | 23.2±1.5 | 6.83±2.92 | 141±19 | 85±10 | 1.52±0.48 | 2.15(1.69,2.99) | 87.84±8.54 |
MHO组 | 6 394 | 49.1±10.3 | 27.8±2.6 | 5.11±1.08 | 125±20 | 81±11 | 1.56±0.37 | 1.19(0.90,1.56) | 86.95±9.12 |
MUO组 | 3 213 | 55.9±9.1 | 28.9±2.9 | 6.51±2.58 | 144±20 | 88±11 | 1.54±0.47 | 2.12(1.70,2.91) | 93.65±8.38 |
检验统计量值 | 1 089.49 | 13 577.90 | 1 247.89 | 2 221.82 | 1 463.69 | 17.38 | 5 899.87a | 3 630.85 | |
P值 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | |
组别 | 总胆固醇(mmol/L) | 受教育程度[名(%)] | 糖尿病[名(%)] | 高血压[名(%)] | 服用调脂药[名(%)] | 吸烟[名(%)] | 饮酒[名(%)] | 体育锻炼[名(%)] | |
高中以下 | 高中及以上 | ||||||||
MHNW组 | 4.82±1.01 | 8 048(63.18) | 4 691(36.82) | 340(2.67) | 2 196(17.24) | 53(0.42) | 253(1.99) | 1 035(8.12) | 1461(11.47) |
MUNW组 | 5.29±1.31 | 843(79.53) | 217(20.47) | 372(35.09) | 740(69.81) | 49(4.52) | 37(3.49) | 37(3.49) | 207(19.53) |
MHO组 | 4.97±1.26 | 4 745(74.21) | 1 649(25.79) | 206(3.22) | 1 965(30.73) | 30(0.47) | 166(2.60) | 430(6.73) | 881(13.78) |
MUO组 | 5.34±1.30 | 2 584(80.42) | 629(19.58) | 978(30.44) | 2 509(78.09) | 134(4.17) | 162(5.04) | 151(4.70) | 654(20.35) |
检验统计量值 | 219.34 | 535.98b | 3 900.55b | 5 141.44b | 462.10b | 96.34b | 70.94b | 204.67b | |
P值 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
特征 | 模型1 | 模型2 | 模型3 |
---|---|---|---|
MHNW | 1.00 | 1.00 | 1.00 |
MUNW | 1.49(0.94~2.39) | 1.51(0.94~2.42) | 1.54(0.96~2.46) |
MHO | 1.41(1.10~1.80)a | 1.42(1.11~1.82)a | 1.42(1.11~1.82)a |
MUO | 1.53(1.13~2.07)a | 1.57(1.15~2.13)a | 1.59(1.17~2.17)a |
Table 2 Multivariate Cox proportional hazard regression analysis of different metabolic obesity phenotypes on breast cancer
特征 | 模型1 | 模型2 | 模型3 |
---|---|---|---|
MHNW | 1.00 | 1.00 | 1.00 |
MUNW | 1.49(0.94~2.39) | 1.51(0.94~2.42) | 1.54(0.96~2.46) |
MHO | 1.41(1.10~1.80)a | 1.42(1.11~1.82)a | 1.42(1.11~1.82)a |
MUO | 1.53(1.13~2.07)a | 1.57(1.15~2.13)a | 1.59(1.17~2.17)a |
特征 | 模型1 | 模型2 | 模型3 |
---|---|---|---|
绝经前 | |||
MHNW | 1.00 | 1.00 | 1.00 |
MUNW | 0.90(0.28~2.85) | 0.90(0.28~2.88) | 0.90(0.28~2.87) |
MHO | 1.17(0.83~1.66) | 1.20(0.84~1.69) | 1.20(0.84~1.69) |
MUO | 1.64(0.99~2.73) | 1.67(1.00~2.80) | 1.69(1.01~2.83)a |
绝经后 | |||
MHNW | 1.00 | 1.00 | 1.00 |
MUNW | 1.78(1.05~3.02)a | 1.81(1.07~3.08)a | 1.85(1.09~3.14)a |
MHO | 1.48(1.05~2.10)a | 1.50(1.06~2.13)a | 1.50(1.06~2.13)a |
MUO | 1.49(1.01~2.18)a | 1.53(1.04~2.24)a | 1.55(1.05~2.28)a |
Table 3 Multivariate Cox proportional hazard regression analysis of different metabolic obesity phenotypes on breast cancer by menopausal status
特征 | 模型1 | 模型2 | 模型3 |
---|---|---|---|
绝经前 | |||
MHNW | 1.00 | 1.00 | 1.00 |
MUNW | 0.90(0.28~2.85) | 0.90(0.28~2.88) | 0.90(0.28~2.87) |
MHO | 1.17(0.83~1.66) | 1.20(0.84~1.69) | 1.20(0.84~1.69) |
MUO | 1.64(0.99~2.73) | 1.67(1.00~2.80) | 1.69(1.01~2.83)a |
绝经后 | |||
MHNW | 1.00 | 1.00 | 1.00 |
MUNW | 1.78(1.05~3.02)a | 1.81(1.07~3.08)a | 1.85(1.09~3.14)a |
MHO | 1.48(1.05~2.10)a | 1.50(1.06~2.13)a | 1.50(1.06~2.13)a |
MUO | 1.49(1.01~2.18)a | 1.53(1.04~2.24)a | 1.55(1.05~2.28)a |
特征 | 模型1 | 模型2 | 模型3 |
---|---|---|---|
MHNW | 1.00 | 1.00 | 1.00 |
MUNW | 1.48(0.91~2.42) | 1.49(0.91~2.44) | 1.52(0.93~2.48) |
MHO | 1.42(1.10~1.83)a | 1.44(1.12~1.85)a | 1.44(1.12~1.85)a |
MUO | 1.54(1.12~2.11)a | 1.57(1.14~2.17)a | 1.59(1.16~2.20)a |
Table 4 Sensitivity analysis
特征 | 模型1 | 模型2 | 模型3 |
---|---|---|---|
MHNW | 1.00 | 1.00 | 1.00 |
MUNW | 1.48(0.91~2.42) | 1.49(0.91~2.44) | 1.52(0.93~2.48) |
MHO | 1.42(1.10~1.83)a | 1.44(1.12~1.85)a | 1.44(1.12~1.85)a |
MUO | 1.54(1.12~2.11)a | 1.57(1.14~2.17)a | 1.59(1.16~2.20)a |
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