Chinese General Practice ›› 2024, Vol. 27 ›› Issue (06): 717-722.DOI: 10.12114/j.issn.1007-9572.2023.0305
Special Issue: 女性健康最新文章合集
• Original Research • Previous Articles Next Articles
Received:
2023-04-20
Revised:
2023-07-15
Published:
2024-02-20
Online:
2023-11-21
Contact:
WU Xiaoke
通讯作者:
吴效科
作者简介:
基金资助:
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URL: https://www.chinagp.net/EN/10.12114/j.issn.1007-9572.2023.0305
组别 | 例数 | 年龄(岁) | 尝试妊娠时间(月) | 糖尿病家族史[例(%)] | 高血压家族史[例(%)] | 体质量(kg) | BMI(kg/m2) | WC(cm) | WHR | SBP(mmHg) |
---|---|---|---|---|---|---|---|---|---|---|
无高脂血症组 | 290 | 27.3±2.9 | 19.83±14.90 | 45(15.51) | 101(34.82) | 54.8±5.3 | 21.2±1.5 | 78.37±7.12 | 0.84±0.06 | 110±10 |
高脂血症组 | 138 | 28.8±3.5 | 25.35±20.28 | 33(23.91) | 59(42.75) | 56.8±5.4 | 22.0±1.4 | 81.32±7.12 | 0.86±0.08 | 111±9 |
检验统计量值 | -4.567 | -2.853 | 4.423a | 2.509a | -3.567 | -5.705 | -4.016 | -3.653 | -1.034 | |
P值 | <0.001 | 0.005 | 0.035 | 0.113 | <0.001 | <0.001 | <0.001 | <0.001 | 0.301 | |
组别 | DBP[M(QR),mmHg] | FT(ng/L) | TT(nmol/L) | LH(U/L) | FSH(U/L) | SHBG(nmol/L) | AMH(μg/L) | FAI[M(QR)] | FINS[M(QR),pmol/L] | |
无高脂血症组 | 70(10) | 2.18±0.85 | 1.68±0.62 | 12.10±6.56 | 6.20±1.61 | 55.66±31.48 | 13.27±6.30 | 3.21(3.19) | 50.74(40.44) | |
高脂血症组 | 72(10) | 2.24±0.83 | 1.60±0.68 | 11.50±6.51 | 6.13±1.81 | 37.21±20.24 | 11.90±6.69 | 5.00(4.94) | 68.31(54.84) | |
检验统计量值 | -0.121b | -0.642 | 1.207 | 0.887 | 0.399 | 7.223 | 2.065 | 4.406b | 5.289b | |
P值 | 0.904 | 0.521 | 0.228 | 0.376 | 0.690 | <0.001 | 0.040 | <0.001 | <0.001 | |
组别 | FBG(mmol/L) | HOMA-IR[M(QR)] | HDL(mmol/L) | LDL(mmol/L) | TC(mmol/L) | TG(mmol/L) | ApoA(g/L) | ApoB(g/L) | LP(mg/L) | |
无高脂血症组 | 4.96±0.75 | 1.61(1.34) | 1.46±0.28 | 2.76±0.63 | 4.53±0.74 | 1.07±0.40 | 1.59±0.25 | 0.77±0.18 | 134.49±107.26 | |
高脂血症组 | 4.98±1.03 | 2.27(1.90) | 1.14±0.39 | 3.10±1.08 | 4.89±1.42 | 1.98±1.07 | 1.45±0.38 | 0.96±0.31 | 130.77±104.90 | |
检验统计量值 | -0.205 | 5.027b | 8.581 | -3.443 | -2.778 | -9.804 | 4.052 | -6.784 | 0.337 | |
P值 | 0.838 | <0.001 | <0.001 | <0.001 | 0.001 | <0.001 | <0.001 | <0.001 | 0.737 | |
组别 | ALT[M(QR),U/L] | AST(U/L) | LDH(U/L) | CYSC(mg/L) | HCY(μmol/L) | TBA[M(QR),μmol/L] | TB(μmol/L) | DB(μmol/L) | IB(μmol/L) | |
无高脂血症组 | 5.00(4.00) | 11.58±4.86 | 77.96±37.07 | 0.45±0.14 | 7.82±4.93 | 1.55(1.93) | 7.00±3.32 | 2.53±1.39 | 4.45±2.12 | |
高脂血症组 | 7.00(7.00) | 12.93±7.26 | 97.06±43.80 | 0.45±0.14 | 8.07±4.51 | 1.20(2.20) | 6.14±3.18 | 2.15±1.34 | 4.19±2.13 | |
检验统计量值 | 3.610 b | -1.949 | -4.591 | -0.604 | -0.491 | -1.564 b | 2.492 | 2.613 | 1.153 | |
P值 | <0.001 | 0.053 | <0.001 | 0.546 | 0.623 | 0.118 | 0.013 | 0.009 | 0.250 |
Table 1 Comparison of clinical characteristics and biochemical indices between two groups of patients
组别 | 例数 | 年龄(岁) | 尝试妊娠时间(月) | 糖尿病家族史[例(%)] | 高血压家族史[例(%)] | 体质量(kg) | BMI(kg/m2) | WC(cm) | WHR | SBP(mmHg) |
---|---|---|---|---|---|---|---|---|---|---|
无高脂血症组 | 290 | 27.3±2.9 | 19.83±14.90 | 45(15.51) | 101(34.82) | 54.8±5.3 | 21.2±1.5 | 78.37±7.12 | 0.84±0.06 | 110±10 |
高脂血症组 | 138 | 28.8±3.5 | 25.35±20.28 | 33(23.91) | 59(42.75) | 56.8±5.4 | 22.0±1.4 | 81.32±7.12 | 0.86±0.08 | 111±9 |
检验统计量值 | -4.567 | -2.853 | 4.423a | 2.509a | -3.567 | -5.705 | -4.016 | -3.653 | -1.034 | |
P值 | <0.001 | 0.005 | 0.035 | 0.113 | <0.001 | <0.001 | <0.001 | <0.001 | 0.301 | |
组别 | DBP[M(QR),mmHg] | FT(ng/L) | TT(nmol/L) | LH(U/L) | FSH(U/L) | SHBG(nmol/L) | AMH(μg/L) | FAI[M(QR)] | FINS[M(QR),pmol/L] | |
无高脂血症组 | 70(10) | 2.18±0.85 | 1.68±0.62 | 12.10±6.56 | 6.20±1.61 | 55.66±31.48 | 13.27±6.30 | 3.21(3.19) | 50.74(40.44) | |
高脂血症组 | 72(10) | 2.24±0.83 | 1.60±0.68 | 11.50±6.51 | 6.13±1.81 | 37.21±20.24 | 11.90±6.69 | 5.00(4.94) | 68.31(54.84) | |
检验统计量值 | -0.121b | -0.642 | 1.207 | 0.887 | 0.399 | 7.223 | 2.065 | 4.406b | 5.289b | |
P值 | 0.904 | 0.521 | 0.228 | 0.376 | 0.690 | <0.001 | 0.040 | <0.001 | <0.001 | |
组别 | FBG(mmol/L) | HOMA-IR[M(QR)] | HDL(mmol/L) | LDL(mmol/L) | TC(mmol/L) | TG(mmol/L) | ApoA(g/L) | ApoB(g/L) | LP(mg/L) | |
无高脂血症组 | 4.96±0.75 | 1.61(1.34) | 1.46±0.28 | 2.76±0.63 | 4.53±0.74 | 1.07±0.40 | 1.59±0.25 | 0.77±0.18 | 134.49±107.26 | |
高脂血症组 | 4.98±1.03 | 2.27(1.90) | 1.14±0.39 | 3.10±1.08 | 4.89±1.42 | 1.98±1.07 | 1.45±0.38 | 0.96±0.31 | 130.77±104.90 | |
检验统计量值 | -0.205 | 5.027b | 8.581 | -3.443 | -2.778 | -9.804 | 4.052 | -6.784 | 0.337 | |
P值 | 0.838 | <0.001 | <0.001 | <0.001 | 0.001 | <0.001 | <0.001 | <0.001 | 0.737 | |
组别 | ALT[M(QR),U/L] | AST(U/L) | LDH(U/L) | CYSC(mg/L) | HCY(μmol/L) | TBA[M(QR),μmol/L] | TB(μmol/L) | DB(μmol/L) | IB(μmol/L) | |
无高脂血症组 | 5.00(4.00) | 11.58±4.86 | 77.96±37.07 | 0.45±0.14 | 7.82±4.93 | 1.55(1.93) | 7.00±3.32 | 2.53±1.39 | 4.45±2.12 | |
高脂血症组 | 7.00(7.00) | 12.93±7.26 | 97.06±43.80 | 0.45±0.14 | 8.07±4.51 | 1.20(2.20) | 6.14±3.18 | 2.15±1.34 | 4.19±2.13 | |
检验统计量值 | 3.610 b | -1.949 | -4.591 | -0.604 | -0.491 | -1.564 b | 2.492 | 2.613 | 1.153 | |
P值 | <0.001 | 0.053 | <0.001 | 0.546 | 0.623 | 0.118 | 0.013 | 0.009 | 0.250 |
变量 | B | SE | Wald χ2值 | P值 | OR(95%CI) |
---|---|---|---|---|---|
年龄 | 0.157 | 0.04 | 15.718 | <0.001 | 1.170(1.083~1.264) |
BMI | 0.299 | 0.089 | 11.334 | 0.001 | 1.348(1.133~1.604) |
HOMA-IR | 0.159 | 0.055 | 8.272 | 0.004 | 1.172(1.052~1.306) |
SHBG | -0.022 | 0.006 | 15.402 | <0.001 | 0.979(0.968~0.989) |
LDH | 0.009 | 0.003 | 7.076 | 0.008 | 1.009(1.002~1.015) |
Table 2 Multivariate Logistic regression analysis of the prevalence of hyperlipidemia in PCOS patients with normal BMI
变量 | B | SE | Wald χ2值 | P值 | OR(95%CI) |
---|---|---|---|---|---|
年龄 | 0.157 | 0.04 | 15.718 | <0.001 | 1.170(1.083~1.264) |
BMI | 0.299 | 0.089 | 11.334 | 0.001 | 1.348(1.133~1.604) |
HOMA-IR | 0.159 | 0.055 | 8.272 | 0.004 | 1.172(1.052~1.306) |
SHBG | -0.022 | 0.006 | 15.402 | <0.001 | 0.979(0.968~0.989) |
LDH | 0.009 | 0.003 | 7.076 | 0.008 | 1.009(1.002~1.015) |
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