Chinese General Practice ›› 2022, Vol. 25 ›› Issue (27): 3358-3364.DOI: 10.12114/j.issn.1007-9572.2022.0263
Special Issue: 老年问题最新文章合集
• Article • Previous Articles Next Articles
Received:
2022-03-12
Revised:
2022-04-20
Published:
2022-09-20
Online:
2022-06-23
Contact:
Muyun ZHU
About author:
通讯作者:
朱慕云
作者简介:
Add to citation manager EndNote|Ris|BibTeX
URL: https://www.chinagp.net/EN/10.12114/j.issn.1007-9572.2022.0263
组别 | 例数 | 性别〔n(%)〕 | 年龄( | BMI( | 吸烟量( | PMcsa( | PMI( | |
---|---|---|---|---|---|---|---|---|
男 | 女 | |||||||
GOLDⅠ级组 | 47 | 37(78.7) | 10(21.3) | 69.0±5.9 | 24.0±3.1 | 24.37±12.68 | 23.64±8.30 | 8.48±2.71 |
GOLDⅡ级组 | 88 | 71(80.7) | 17(19.3) | 71.1±7.3 | 23.5±3.4 | 25.35±13.69 | 19.94±5.74b | 7.21±1.97b |
GOLDⅢ级组 | 84 | 70(83.3) | 14(16.7) | 72.3±7.9 | 22.8±3.3b | 25.36±13.83 | 16.78±5.00bc | 6.04±1.70bc |
GOLDⅣ级组 | 51 | 42(82.3) | 9(17.7) | 71.0±6.6 | 21.4±3.0bcd | 26.40±15.69 | 14.19±4.60bcd | 5.22±1.61bcd |
F(χ2)值 | 0.491a | 2.292 | 6.587 | 0.056 | 25.902 | 27.776 | ||
P值 | 0.921 | 0.078 | 0.001 | 0.982 | <0.001 | <0.001 | ||
组别 | PMD( | FEV1%pred( | FEV1( | FVC( | 肺体积( | 右肺LAA%( | 左肺LAA%( | 总肺LAA%( |
GOLDⅠ级组 | 36.49±12.42 | 87.23±7.14 | 2.00±0.46 | 2.90±0.62 | 5.18±1.07 | 13.21±6.65 | 13.81±6.95 | 13.54±6.77 |
GOLDⅡ级组 | 35.01±10.40 | 61.14±7.89b | 1.55±0.38b | 2.49±0.66b | 5.31±1.36 | 15.37±8.93b | 15.32±8.37b | 15.35±8.59b |
GOLDⅢ级组 | 32.97±11.46b | 41.17±6.05bc | 1.19±0.36bc | 2.22±0.65bc | 5.48±1.40 | 18.66±7.77bc | 18.86±8.66bc | 18.89±7.90bc |
GOLDⅣ级组 | 30.99±8.84bcd | 25.86±4.45bcd | 0.91±0.43bcd | 1.82±0.69bcd | 5.36±0.99 | 25.23±8.42bcd | 24.24±7.30bcd | 24.88±7.85bcd |
F(χ2)值 | 2.673 | 851.052 | 73.969 | 24.910 | 0.621 | 22.600 | 18.319 | 21.649 |
P值 | 0.048 | <0.001 | <0.001 | <0.001 | 0.602 | <0.001 | <0.001 | <0.001 |
Table 1 Comparison of clinical data of patients with different grades of COPD
组别 | 例数 | 性别〔n(%)〕 | 年龄( | BMI( | 吸烟量( | PMcsa( | PMI( | |
---|---|---|---|---|---|---|---|---|
男 | 女 | |||||||
GOLDⅠ级组 | 47 | 37(78.7) | 10(21.3) | 69.0±5.9 | 24.0±3.1 | 24.37±12.68 | 23.64±8.30 | 8.48±2.71 |
GOLDⅡ级组 | 88 | 71(80.7) | 17(19.3) | 71.1±7.3 | 23.5±3.4 | 25.35±13.69 | 19.94±5.74b | 7.21±1.97b |
GOLDⅢ级组 | 84 | 70(83.3) | 14(16.7) | 72.3±7.9 | 22.8±3.3b | 25.36±13.83 | 16.78±5.00bc | 6.04±1.70bc |
GOLDⅣ级组 | 51 | 42(82.3) | 9(17.7) | 71.0±6.6 | 21.4±3.0bcd | 26.40±15.69 | 14.19±4.60bcd | 5.22±1.61bcd |
F(χ2)值 | 0.491a | 2.292 | 6.587 | 0.056 | 25.902 | 27.776 | ||
P值 | 0.921 | 0.078 | 0.001 | 0.982 | <0.001 | <0.001 | ||
组别 | PMD( | FEV1%pred( | FEV1( | FVC( | 肺体积( | 右肺LAA%( | 左肺LAA%( | 总肺LAA%( |
GOLDⅠ级组 | 36.49±12.42 | 87.23±7.14 | 2.00±0.46 | 2.90±0.62 | 5.18±1.07 | 13.21±6.65 | 13.81±6.95 | 13.54±6.77 |
GOLDⅡ级组 | 35.01±10.40 | 61.14±7.89b | 1.55±0.38b | 2.49±0.66b | 5.31±1.36 | 15.37±8.93b | 15.32±8.37b | 15.35±8.59b |
GOLDⅢ级组 | 32.97±11.46b | 41.17±6.05bc | 1.19±0.36bc | 2.22±0.65bc | 5.48±1.40 | 18.66±7.77bc | 18.86±8.66bc | 18.89±7.90bc |
GOLDⅣ级组 | 30.99±8.84bcd | 25.86±4.45bcd | 0.91±0.43bcd | 1.82±0.69bcd | 5.36±0.99 | 25.23±8.42bcd | 24.24±7.30bcd | 24.88±7.85bcd |
F(χ2)值 | 2.673 | 851.052 | 73.969 | 24.910 | 0.621 | 22.600 | 18.319 | 21.649 |
P值 | 0.048 | <0.001 | <0.001 | <0.001 | 0.602 | <0.001 | <0.001 | <0.001 |
项目 | FEV1%pred | FEV1 | FVC | |||
---|---|---|---|---|---|---|
r值 | P值 | r值 | P值 | r值 | P值 | |
PMcsa | 0.589 | <0.01 | 0.326 | <0.01 | 0.419 | <0.01 |
PMI | 0.623 | <0.01 | 0.411 | <0.01 | 0.410 | <0.01 |
PMD | 0.232 | <0.01 | 0.227 | <0.01 | 0.281 | <0.01 |
右肺LAA% | -0.525 | <0.01 | -0.270 | <0.01 | -0.091 | 0.13 |
左肺LAA% | -0.501 | <0.01 | -0.251 | <0.01 | -0.044 | 0.47 |
总肺LAA% | -0.538 | <0.01 | -0.273 | <0.01 | -0.064 | 0.29 |
肺体积 | -0.061 | 0.31 | 0.014 | 0.81 | 0.149 | 0.01 |
Table 2 Correlation analysis of pectoralis major muscle parameters,low attenuation area ratio and lung function
项目 | FEV1%pred | FEV1 | FVC | |||
---|---|---|---|---|---|---|
r值 | P值 | r值 | P值 | r值 | P值 | |
PMcsa | 0.589 | <0.01 | 0.326 | <0.01 | 0.419 | <0.01 |
PMI | 0.623 | <0.01 | 0.411 | <0.01 | 0.410 | <0.01 |
PMD | 0.232 | <0.01 | 0.227 | <0.01 | 0.281 | <0.01 |
右肺LAA% | -0.525 | <0.01 | -0.270 | <0.01 | -0.091 | 0.13 |
左肺LAA% | -0.501 | <0.01 | -0.251 | <0.01 | -0.044 | 0.47 |
总肺LAA% | -0.538 | <0.01 | -0.273 | <0.01 | -0.064 | 0.29 |
肺体积 | -0.061 | 0.31 | 0.014 | 0.81 | 0.149 | 0.01 |
变量 | 系数(95%CI) | SE | t值 | P值 |
---|---|---|---|---|
常量 | 35.519(25.852,45.186) | 4.910 | 7.234 | <0.001 |
性别 | 10.215(4.064,16.365) | 3.124 | 3.270 | 0.001 |
总肺LAA% | -0.698(-0.950,-0.446) | 0.128 | -5.456 | <0.001 |
PMcsa | 1.506(1.154,1.857) | 0.178 | 8.436 | <0.001 |
Table 3 Multiple linear regression analysis of PMcsa,LAA% and lung function indicators in COPD patiens
变量 | 系数(95%CI) | SE | t值 | P值 |
---|---|---|---|---|
常量 | 35.519(25.852,45.186) | 4.910 | 7.234 | <0.001 |
性别 | 10.215(4.064,16.365) | 3.124 | 3.270 | 0.001 |
总肺LAA% | -0.698(-0.950,-0.446) | 0.128 | -5.456 | <0.001 |
PMcsa | 1.506(1.154,1.857) | 0.178 | 8.436 | <0.001 |
项目 | 男 | 女 | ||||||
---|---|---|---|---|---|---|---|---|
AUC(95%CI) | 截断值(%) | 灵敏度 | 特异度 | AUC(95%CI) | 截断值(%) | 灵敏度 | 特异度 | |
右肺LAA% | 0.832(0.769,0.885) | 15.25 | 0.841 | 0.727 | 0.844(0.735,0.953) | 14.62 | 0.792 | 0.801 |
左肺LAA% | 0.827(0.777,0.887) | 15.85 | 0.833 | 0.715 | 0.801(0.669,0.920) | 13.85 | 0.625 | 0.754 |
总肺LAA% | 0.834(0.778,0.891) | 16.71 | 0.807 | 0.784 | 0.845(0.737,0.954) | 13.61 | 0.792 | 0.753 |
PMcsa | 0.809(0.742,0.858) | 19.05 | 0.667 | 0.881 | 0.839(0.726,0.953) | 13.96 | 0.769 | 0.871 |
Table 4 Efficacy of PMcsa and low attenuation area ratio in predicting FEV1% pred<50% in patients of different genders
项目 | 男 | 女 | ||||||
---|---|---|---|---|---|---|---|---|
AUC(95%CI) | 截断值(%) | 灵敏度 | 特异度 | AUC(95%CI) | 截断值(%) | 灵敏度 | 特异度 | |
右肺LAA% | 0.832(0.769,0.885) | 15.25 | 0.841 | 0.727 | 0.844(0.735,0.953) | 14.62 | 0.792 | 0.801 |
左肺LAA% | 0.827(0.777,0.887) | 15.85 | 0.833 | 0.715 | 0.801(0.669,0.920) | 13.85 | 0.625 | 0.754 |
总肺LAA% | 0.834(0.778,0.891) | 16.71 | 0.807 | 0.784 | 0.845(0.737,0.954) | 13.61 | 0.792 | 0.753 |
PMcsa | 0.809(0.742,0.858) | 19.05 | 0.667 | 0.881 | 0.839(0.726,0.953) | 13.96 | 0.769 | 0.871 |
项目 | 男 | 女 | ||||||
---|---|---|---|---|---|---|---|---|
AUC(95%CI) | 截断值(%) | 灵敏度 | 特异度 | AUC(95%CI) | 截断值(%) | 灵敏度 | 特异度 | |
右肺LAA% | 0.830(0.753,0.898) | 9.85 | 0.861 | 0.647 | 0.805(0.657,0.933) | 7.25 | 0.897 | 0.641 |
左肺LAA% | 0.815(0.738,0.885) | 9.80 | 0.873 | 0.638 | 0.817(0.697,0.938) | 6.98 | 0.825 | 0.653 |
总肺LAA% | 0.831(0.760,0.899) | 9.28 | 0.887 | 0.643 | 0.807(0.675,0.939) | 7.23 | 0.882 | 0.624 |
PMcsa | 0.844(0.784,0.907) | 24.82 | 0.667 | 0.881 | 0.846(0.714,0.977) | 15.03 | 0.755 | 0.811 |
Table 5 Efficacy of PMcsa and low attenuation area ratio in predicting FEV1% pred<80% in patients of different genders
项目 | 男 | 女 | ||||||
---|---|---|---|---|---|---|---|---|
AUC(95%CI) | 截断值(%) | 灵敏度 | 特异度 | AUC(95%CI) | 截断值(%) | 灵敏度 | 特异度 | |
右肺LAA% | 0.830(0.753,0.898) | 9.85 | 0.861 | 0.647 | 0.805(0.657,0.933) | 7.25 | 0.897 | 0.641 |
左肺LAA% | 0.815(0.738,0.885) | 9.80 | 0.873 | 0.638 | 0.817(0.697,0.938) | 6.98 | 0.825 | 0.653 |
总肺LAA% | 0.831(0.760,0.899) | 9.28 | 0.887 | 0.643 | 0.807(0.675,0.939) | 7.23 | 0.882 | 0.624 |
PMcsa | 0.844(0.784,0.907) | 24.82 | 0.667 | 0.881 | 0.846(0.714,0.977) | 15.03 | 0.755 | 0.811 |
[1] |
陈亚红. 2019年GOLD慢性阻塞性肺疾病诊断、治疗及预防全球策略解读[J]. 中国医学前沿杂志(电子版),2019,11(1):1-14. DOI:10.12037/YXQY.2019.01-01.
|
[2] |
|
[3] |
|
[4] |
刘金良,庞军,李晓冬,等. 慢性阻塞性肺疾病患者胸部定量CT参数与肺功能检测指标相关性分析[J]. 临床肺科杂志,2020,25(12):1831-1835. DOI:10.3969/j.issn.1009-6663.2020.12.012.
|
[5] |
|
[6] |
沈宁,贺蓓. 肺功能检查在慢性阻塞性肺疾病诊断及治疗中的临床意义[J]. 中华结核和呼吸杂志,2019,42(1):73-78. DOI:10.3760/cma.j.issn.1001-0939.2019.01.023.
|
[7] |
文富强,申永春,陈磊. 肺功能检查在中国慢性阻塞性肺疾病患者中的实践:挑战与对策[J]. 中华结核和呼吸杂志,2017,40(12):891-893. DOI:10.3760/cma.j.issn.1001-0939.2017.12.004.
|
[8] |
中华医学会,中华医学会杂志社,中华医学会全科医学分会,等. 常规肺功能检查基层指南(2018年)[J]. 中华全科医师杂志,2019,18(6):511-518. DOI:10.3760/cma.j.issn.1671-7368.2019.06.003.
|
[9] |
|
[10] |
李艳,高俊刚,郭佑民,等. 支气管炎型和肺气肿型COPD患者CT定量指标及肺功能的纵向变化研究[J]. 临床放射学杂志,2020,39(6):1104-1107. DOI:10.13437/j.cnki.jcr.2020.06.017.
|
[11] |
|
[12] |
|
[13] |
|
[14] |
|
[15] |
|
[16] |
|
[17] |
任涛. 基于MSCT慢性阻塞性肺疾病定量参数对肺功能指标的预测价值[D]. 银川:宁夏医科大学,2021.
|
[18] |
董中兴,沈慧君,龚李艳,等. 肺叶低密度区容积百分比对慢性阻塞性肺病患者肺功能受损程度的评估作用[J]. 内科急危重症杂志,2017,23(5):365-367,374. DOI:10.11768/nkjwzzzz20170504.
|
[19] |
兰长青,王洁,黄梅萍,等. CT肺气肿指数及空间分布对慢性阻塞性肺疾病肺损伤的评估价值[J]. 中国临床医学影像杂志,2021,32(5):320-325. DOI:10.12117/jccmi.2021.05.004.
|
[20] |
|
[21] |
|
[1] | QIN Fengyin, ZHANG Qishan, LAI Jinjia, HUANG Yimin, HAN Guoyin, SUN Xinglan, WANG Fen, TAN Yibing. Current Status and Influencing Factors of the Intention to Screen for High-risk Stroke among Community Residents in Guangdong [J]. Chinese General Practice, 2023, 26(34): 4283-4289. |
[2] | FENG Xiaoyu, LI Wanling, LYU Siman, NI Cuiping, WANG Haocheng, LIU Yu. International Research Status and Hot Spot Analysis of InterRAI HC Based on Bibliometrics [J]. Chinese General Practice, 2023, 26(34): 4351-4358. |
[3] | GU Hanxin, LIU Yang, LIU Yuanli. Falls Prevention Intervention for Community-dwelling Older Adults from the Perspective of Policy Tools: an International Comparative Study [J]. Chinese General Practice, 2023, 26(34): 4231-4238. |
[4] | HAO Aihua, ZENG Weilin, LI Guanhai, XIA Yinghua, CHEN Liang. Current Situation of the Construction of Family Doctor Team: an Investigation Based on the Perspective of General Practitioners [J]. Chinese General Practice, 2023, 26(34): 4261-4268. |
[5] | LI Dianjiang, PAN Enchun, SUN Zhongming, WEN Jinbo, WANG Miaomiao, WU Ming, SHEN Chong. The Current Status and Influencing Factors of Clinical Inertia in Type 2 Diabetes Patients in Community [J]. Chinese General Practice, 2023, 26(34): 4296-4301. |
[6] | WANG Yue, CHEN Qing, LIU Lurong. Detection Rate of Depression and Its Influencing Factors in Chinese Elderly: a Meta-analysis [J]. Chinese General Practice, 2023, 26(34): 4329-4335. |
[7] | YU Xinyan, ZHAO Jun, ZHAO Xiaoye, JIANG Qingru, CHEN Yatian, WANG Yan, ZHANG Haicheng. Application of Mobile Smart Healthcare in the Prevention and Control of Cardiovascular Diseases in Elderly Patients with Chronic Diseases in Primary Care [J]. Chinese General Practice, 2023, 26(33): 4167-4172. |
[8] | WANG Yu, CHEN Yan, HAN Yuanyuan, XU Qing, CHEN Shengyue, LYU Zhibo, LU Chuan, ZHENG Mingxin, ZHAO Xin. Platelet-lymphocyte Ratio Predicts In-hospital Mortality in Elderly Patients with Acute Myocardial Infarction [J]. Chinese General Practice, 2023, 26(33): 4137-4142. |
[9] | WANG Lina, GAO Pengfei, CAO Fan, GE Ying, YAN Wei, HE Daikun. Analysis of the Prevalence and Influencing Factors of Non-alcoholic Fatty Liver Disease in Different Gender Groups [J]. Chinese General Practice, 2023, 26(33): 4143-4151. |
[10] | ZHOU Yuyu, GAO Chuan, CUI Puan, WANG Yaping, HE Zhong. Influencing Factors of Shared Decision Making between Doctors and Patients in Menopausal Hormone Therapy in Patients with Menopausal Syndrome [J]. Chinese General Practice, 2023, 26(33): 4181-4186. |
[11] | XIN Gongkai, CONG Xin, YUAN Lei, CHENG Yuetong, NI Cuiping, ZHANG Weiwei, ZHANG Pingping, LIU Yu. Research Progress on Comprehensive Assessment Tools for the Elderly with Dementia [J]. Chinese General Practice, 2023, 26(33): 4103-4109. |
[12] | ZHANG Jin, DING Zhiguo, QI Shuo, LI Ying, LI Weiqiang, ZHANG Yuanyuan, ZHOU Tong. Relationship between Serum Thyroid Hormone Levels and Prognosis during Hospitalization in Heart Failure Patients [J]. Chinese General Practice, 2023, 26(33): 4125-4129. |
[13] | LIANG Xuan, NA Feiyang, QIN Mengyao, YANG Hui, GUO Li, GUO Qi, REN Lei, CHEN De, LIU Donghai, ZHANG Rongfang. Clinical Characteristics and Influencing Factors of Bronchial Asthma Combined with Obstructive Sleep Apnea-hypopnea Syndrome in Children [J]. Chinese General Practice, 2023, 26(33): 4225-4230. |
[14] | LI Qianqian, CHEN Xunrui, ZHANG Wenying, YUAN Haihua, ZHANG Yanjie, JIANG Bin, LIU Feng. Demand and Influencing Factors for Community Health Services during Chemotherapy of Patients with Advanced Cancer [J]. Chinese General Practice, 2023, 26(33): 4173-4180. |
[15] | ZHANG Jifang, CHEN Fang, TANG Jiawen, LI Hongliang. Predictive Value of Tumor Budding and Tumor-infiltrating Lymphocytes on Lymph Node Metastasis of Esophageal Squamous Cell Carcinoma [J]. Chinese General Practice, 2023, 26(32): 4038-4042. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||