The Interpretation about International Consensus on the Prediction and Identification of Long-term Damage to Survivors of Severe Illness by the Critical Care Medical Association in 2020

doi:10.12114/j.issn.1007-9572.2021.00.421

Abstract

Abstract: This paper interprets "International Consensus on the Prediction and Identification of Long-term Damage to Survivors of Severe Illness by the Critical Care Medical Association"，published by the American Society for Critical Care Medical Association in November 2020.On the basis of the second "Improving Long-term Outcomes on Discharging from the Hospital for Intensive Care Survivors：a Report of Stakeholder Meetings" in 2012，three new aspects including how to identify high-risk survivors，which assessment and screening tools to use，and the timing of screening for severely ill survivors have been newly added.Considering the fact that there are no guidelines or consensuses specifically on the prediction and identification of long-term damage of survivors of severe illness，the interpretation of the "International Consensus on the Prediction and Identification of Long-term Damage to Survivors of Severe Illness by the Critical Care Medical Association" was intended to provide practical advice to clinical health care workers in China，hoping to improve the outcome of critical care for survivors of severe illness in this study.

Key words: Survivors of severe illness, Severe illness, Long-term damage, Forecasting, Recognition, Consensus, Interpretation

摘要：

本文对美国重症医学会2020年11月发布的《重症医学会关于重症后幸存者远期损害的预测和识别国际共识》进行解读，其在2012年第2次发布的《改善重症监护幸存者出院后的远期结果：利益相关者会议的报告》的基础上，主要新增了如何识别高危幸存者、使用哪些评估及筛查工具、确定重症后幸存者的筛查时机等3方面内容。鉴于国内目前尚无专门针对重症后幸存者远期损害预测和识别方面的指南或共识，故对该国际共识进行解读，旨在为我国临床医护工作者提供实用的建议，以期改善危重症幸存者照护结局。

关键词:

重症幸存者, 重症, 远期损害, 预测, 识别, 共识, 解读

YIN Yue,DENG Yufang,SUN Yajun, et al. The Interpretation about International Consensus on the Prediction and Identification of Long-term Damage to Survivors of Severe Illness by the Critical Care Medical Association in 2020[J]. Chinese General Practice, 2021, 24(12): 1458-1463. DOI: 10.12114/j.issn.1007-9572.2021.00.421.
殷月,邓雨芳,孙亚君等. 2020年美国《重症医学会关于重症后幸存者远期损害的预测和识别国际共识》解读[J]. 中国全科医学, 2021, 24(12): 1458-1463. DOI: 10.12114/j.issn.1007-9572.2021.00.421.

References

［1］MARRA A，PANDHARIPANDE P P，GIRARD T D，et al．Co-occurrence of post-intensive care syndrome problems among 406 survivors of critical illness［J］．Crit Care Med，2018，46（9）：1393-1401．DOI：10.1097/ccm.0000000000003218.

［2］卢新兵，丁四清，余晓.ICU后认知损害发生的相关因素及干预措施的研究进展［J］．中国护理管理，2016，16（8）：1131-1135．DOI：10.3969/j.issn.1672-1756.2016.08.030.

LU X B，DING S Q，YU X.The research progress of related factors and intervention measures of post-ICU cognitive impairment［J］．Chinese Nursing Management，2016，16（8）：1131-1135．DOI：10.3969/j.issn.1672-1756.2016.08.030.

［3］姚丽，丁楠楠，杨丽平，等．重症患者转出ICU后认知损害危险因素的Meta分析［J］．中国护理管理，2018，18（12）：1634-1643．DOI：10.3969/j.issn.1672-1756.2018.12.011.

YAO L，DING N N，YANG L P，et al．Risk factors for cognitive impairment after critical illness：a Meta-analysis［J］．Chinese Nursing Management，2018，18（12）：1634-1643．DOI：10.3969/j.issn.1672-1756.2018.12.011.

［4］NEEDHAM D M，DAVIDSON J，COHEN H，et al．Improving long-term outcomes after discharge from intensive care unit：report from a stakeholders' conference［J］．Crit Care Med，2012，40（2）：502-509．DOI：10.1097/CCM.0b013e318232da75.

［5］ELLIOTT D，DAVIDSON J E，HARVEY M A，et al．Exploring the scope of post-intensive care syndrome therapy and care：engagement of non-critical care providers and survivors in a second stakeholders meeting［J］．Crit Care Med，2014，42（12）：2518-2526．DOI：10.1097/ccm.0000000000000525.

［6］MIKKELSEN M E，STILL M，ANDERSON B J，et al．Society of critical care medicine's international consensus conference on prediction and identification of long-term impairments after critical illness［J］．Crit Care Med，2020，48（11）：1670-1679．DOI：10.1097/CCM.0000000000004586.

［7］MALEY J H，BREWSTER I，MAYORAL I，et al．Resilience in survivors of critical illness in the context of the survivors' experience and recovery［J］．Ann Am Thorac Soc，2016，13（8）：1351-1360．DOI：10.1513/annalsats.201511-782oc.

［8］PATEL M B，JACKSON J C，MORANDI A，et al．Incidence and risk factors for intensive care unit-related post-traumatic stress disorder in veterans and civilians［J］．Am J Respir Cirt Care Med，2016，193：1373．DOI：10.1164/rccm.201506-1158OC.

［9］HERRIDGE M S，MOSS M，HOUGH C L，et al．Recovery and outcomes after the acute respiratory distress syndrome （ARDS） in patients and their family caregivers［J］．Intensive Care Med，2016，42（5）：725-738．DOI：10.1007/s00134-016-4321-8.

［10］WOLTERS A E，SLOOTER A J，VAN DER KOOI A W，et al．Cognitive impairment after intensive care unit admission：a systematic review［J］．Intensive Care Med，2013，39（3）：376-386．DOI：10.1007/s00134-012-2784-9.

［11］DE ROOIJ S E J A，GOVERS A C，KOREVAAR J C，et al．Cognitive，functional，and quality-of-life outcomes of patients aged 80 and older who survived at least 1 year after planned or unplanned surgery or medical intensive care treatment［J］．J Am Geriatr Soc，2008，56（5）：816-822．DOI：10.1111/j.1532-5415.2008.01671.x.

［12］MCPEAKE J，MIKKELSEN M E，QUASIM T，et al．Return to employment after critical illness and its association with psychosocial outcomes：a systematic review and meta-analysis［J］．Ann Am Thorac Soc，2019，6：1304-1311．DOI：10.1513/AnnalsATS.201903-248OC.

［13］MCPEAKE J，SHAW M，IWASHYNA T J，et al．Intensive care syndrome：promoting independence and return to employment （InS：PIRE）：early evaluation of a complex intervention［J］．PLoS One，2017，12：e0188028．DOI：10.1371/journal.pone.0188028.

［14］LEE C M，HERRIDGE M S，MATTE A，et al．Education and support needs during recovery in acute respiratory distress syndrome survivors［J］．Crit Care，2009，13（5）：R153．DOI：10.1186/cc8053.

［15］FIELD K，PRINJHA S，ROWAN K.'One patient amongst many'：a qualitative analysis of intensive care unit patients' experiences of transferring to the general ward［J］．Crit Care，2008，12（1）：R21．DOI：10.1186/cc6795.

［16］赵晶晶.重症患者认知损害和情感障碍及其干预［D］．合肥：安徽医科大学，2016.

ZHAO J J.Cognitive impairment and affective disorder in critical patients and its intervention［D］．Hefei：Anhui Medical University，2016.

［17］邵聪，顾立学，梅永霞，等．重症加强治疗后综合征患者发生认知障碍的危险因素分析［J］．中华危重症急救医学，2017，29（8）：716-720．DOI：10.3760/cma.j.issn.2095-4352.2017.08.009.

SHAO C，GU L X，MEI Y X，et al．Analysis of the risk factors of cognitive impairment in post-intensive care syndrome patient［J］．China Critical Care Emergency Medicine，2017，29（8）：716-720．DOI：10.3760/cma.j.issn.2095-4352.2017.08.009.

［18］李宝宝.成人心脏术后ICU后综合征发生现状及影响因素的研究［D］．济南：山东大学，2018.

LI B B.The present status and influencing factors of post-intensive care syndrome in adult after cardiac surgery［D］．Jinan：Shandong University，2018.

［19］MIKKELSEN M E，JACKSON J C，HOPKINS R O，et al．Peer support as a novel strategy to mitigate post-intensive care syndrome［J］．AACN Adv Crit Care，2016，27：221-229．DOI：10.4037/aacnacc2016667.

［20］MCPEAKE J，HIRSHBERG E L，CHRISTIE L M，et al．Models of peer support to remediate post-intensive care syndrome：a report developed by the society of critical care medicine thrive international peer support collaborative［J］．Crit Care Med，2019，47：e21-27．DOI：10.1097/CCM.0000000000003497.

［21］HAINES K J，MCPEAKE J，HIBBERT E，et al．Enablers and barriers to implementing ICU follow-up clinics and peer support groups following critical illness：the thrive collaboratives［J］．Crit Care Med，2019，47：1194-1200．DOI：10.1097/CCM.0000000000003818.

［22］HAINES K J，SEVIN C M，HIBBERT E，et al．Key mechanisms by which post-ICU activities can improve in-ICU care：results of the international THRIVE collaboratives［J］．Intensive Care Med，2019，45：939-947．DOI：10.1007/s00134-019-05647-5.

［23］OHTAKE P J，LEE A C，SCOTT J C，et al．Physical impairments associated with post-intensive care syndrome：Systematic review based on the World Health Organization's international classification of functioning，disability and health framework［J］．Phys Ther，2018，98：631-645．DOI：10.1093/ptj/pzy059.

［24］NEEDHAM D M，SEPULVEDA K A，DINGLAS V D，et al．Core outcome measures for clinical research in acute respiratory failure survivors：an international modified Delphi consensus study［J］．Am J Respir Crit Care Med，2017，196：1122-1130．DOI：10.1164/rccm.201702-0372OC.

［25］SAKUSIC A，O'HORO J C，DZIADZKO M，et al．Potentially modifiable risk factors for long-term cognitive impairment after critical illness：a systematic review［J］．Mayo Clin Proc，2018，93（1）：68-82．DOI：10.1016/j.mayocp.2017.11.005.

［26］NIKAYIN S，RABIEE A，HASHEM M D，et al．Anxiety symptoms in survivors of critical illness：a systematic review and meta-analysis［J］．Gen Hosp Psychiatry，2016，43：23-29．DOI：10.1016/j.genhosppsych.2016.08.005.

［27］HAINES K J，HIBBERT E，MCPEAKE J，et al．Prediction models for physical，cognitive，and mental health impairments after critical illness：a systematic review and critical appraisal［J］．Crit Care Med，2020，48（12）：1871-1880．DOI：10.1097/CCM.0000000000004659.

［28］Improving Long-Term Outcomes Research for Acute Respiratory Failure［EB/OL］．［2020-11-02］．https：//www.improvelto.com/instruments.Accessed January 15，2020.

［29］LEE C M，HERRIDGE M S，MATTE A，et al．Education and support needs during recovery in acute respiratory distress syndrome survivors［J］．Crit Care，2009，13（5）：R153．DOI：10.1186/cc8053.

［30］MEHRHOLZ J，MÜCKEL S，OEHMICHEN F，et al．First results about recovery of walking function in patients with intensive care unit-acquired muscle weakness from the General Weakness Syndrome Therapy （GymNAST） cohort study［J］．BMJ Open，2015，5（12）：e008828．DOI：10.1136/bmjopen-2015-008828.

[1]	WANG Yu, CHEN Yan, HAN Yuanyuan, XU Qing, CHEN Shengyue, LYU Zhibo, LU Chuan, ZHENG Mingxin, ZHAO Xin. Platelet-lymphocyte Ratio Predicts In-hospital Mortality in Elderly Patients with Acute Myocardial Infarction [J]. Chinese General Practice, 2023, 26(33): 4137-4142.
[2]	ZHANG Jifang, CHEN Fang, TANG Jiawen, LI Hongliang. Predictive Value of Tumor Budding and Tumor-infiltrating Lymphocytes on Lymph Node Metastasis of Esophageal Squamous Cell Carcinoma [J]. Chinese General Practice, 2023, 26(32): 4038-4042.
[3]	LU Guangqi, ZHUANG Minghui, ZHU Liguo, GAO Jinghua, WEI Xu, LI Luguang, YU Jie. Interpretation of Best Practices for Minimally Invasive Lumbar Spinal Stenosis Treatment 2.0 (MIST) : Consensus Guidance from the American Society of Pain and Neuroscience (ASPN) in 2022 [J]. Chinese General Practice, 2023, 26(32): 3995-4000.
[4]	HUANG Jiajie, LAI Honghao, SUN Mingyao, LIU Jianing, ZHAO Weilong, TANG Wenjing, YANG Shuihua, PAN Bei, TIAN Jinhui, MA Xiaoting, GE Long. Interpretation of Update on Consolidated Framework for Implementation Research (CFIR 2.0) [J]. Chinese General Practice, 2023, 26(31): 3863-3871.
[5]	CHENG Jingwei, QIAO Junjun, YIN Zhen, HU Junpeng, WANG Qinghe, LIU Yangqing, WANG Yanfang. Interpretation of ISPAD Clinical Practice Consensus Guidelines 2022: Exercise in Children and Adolescents with Diabetes [J]. Chinese General Practice, 2023, 26(30): 3719-3724.
[6]	WEN Wen, ZHANG Kainan, CHEN Yulan, LI Yu, ZHANG Xiangyang. Correlation of Metabolic Indexes as Predictors with Obstructive Sleep Apnea [J]. Chinese General Practice, 2023, 26(30): 3740-3747.
[7]	CHEN Jing, ZOU Tao, ZHAO Danqing, XIAO Ziwen, WU Xianqing, Chinese Medical Association Psychosomatic Medicine Branch Perinatal Mental Disorders Collaborative Group. Expert Consensus on Screening, Diagnosis and Treatment of Perinatal Mental Disorders [J]. Chinese General Practice, 2023, 26(28): 3463-3470.
[8]	Expert group of expert consensus on the application of ulinastatin in common clinical critical illness. Expert Consensus on the Application of Ulinastatin in Common Clinical Critical Illness [J]. Chinese General Practice, 2023, 26(26): 3207-3219.
[9]	Chinese Medical Association Clinical Pharmacy Branch, Shanghai Medical Association Clinical Pharmacy Branch, Shanghai Pharmacy Association Hospital Pharmacy Professional Committee. Expert Consensus on Construction and Application of the Internet Medical Intelligent Auxiliary Prescription Review System [J]. Chinese General Practice, 2023, 26(25): 3079-3090.
[10]	Climacteric Health Care Branch of Chinese Preventive Medicine Association, Gynecologic Endocrinology and Fertility Professional Committees of China Association for Promotion of Health Science and Technology, Professional Committees of Beijing Association of the Integrating of Traditional and Western Medicine. Chinese Expert Consensus on Clinical Management of Menopause-related Insomnia [J]. Chinese General Practice, 2023, 26(24): 2951-2958.
[11]	ZHANG Yunxu, WANG Tingting, WEI Junling, XING Yanyun, SU Li. A Newly Discovered Disease Affecting Women's Physical and Mental Health: Research Status and Expert Consensus Interpretation of Persistent Genital Arousal Disorder [J]. Chinese General Practice, 2023, 26(23): 2830-2835.
[12]	ZHANG Zhuoran, YU Changhe, AN Yi, HE Xin, GUO Yi, DENG Jinyan, LI Yue, HAN Deng, PI Shanshan, HE Junzhi, CHEN Yue, YE Yong'an, DU Hongbo. Quality Assessment and Recommendations of Clinical Guidelines and Consensuses on Non-alcoholic Fatty Liver Disease: a Comparative Study [J]. Chinese General Practice, 2023, 26(20): 2439-2446.
[13]	WANG Hai, WANG Zhuoli, PEI Honghong, PAN Longfei. Analysis of Risk Factors and Exploration of Predictors of Serious Cases of COVID-19 in Xi'an during the Period of 2021-2022 [J]. Chinese General Practice, 2023, 26(17): 2132-2137.
[14]	LIANG Shanshan, ZHOU Zhihua, LI Chengcheng, CHEN Huijing, ZHOU Shangcheng. Diabetes in China: Burden Analysis between 1990 and 2019 and Incidence Prediction between 2020 and 2030 [J]. Chinese General Practice, 2023, 26(16): 2013-2019.
[15]	MA Yunyun, SONG Yulei, LIANG Xiao, GAO Jiaojiao, QI Xinru, WANG Ye, XU Guihua, BAI Yamei. Value of Reduced Taste Recognition Ability in Early Warning of Mild Cognitive Impairment [J]. Chinese General Practice, 2023, 26(16): 1984-1988,2003.