Chinese General Practice ›› 2022, Vol. 25 ›› Issue (01): 14-19.DOI: 10.12114/j.issn.1007-9572.2021.00.348

Special Issue: 新型冠状病毒肺炎最新文章合集 述评栏目最新文章合集

• Editorial • Previous Articles     Next Articles

Epidemiologic Features and Containment of SARS-CoV-2 Omicron Variant

  

  1. 1.School of Public HealthPeking UniversityBeijing 100191China

    2.Vanke School of Public HealthTsinghua UniversityBeijing 100084China

    *Corresponding authorsLIU MinProfessorDoctoral supervisorE-mailliumin@bjmu.edu.cn

    LIANG WannianProfessorDoctoral supervisorE-mailliangwn@tsinghua.edu.cn

  • Received:2021-12-10 Revised:2021-12-13 Published:2022-01-05 Online:2021-12-29

新型冠状病毒Omicron变异株的流行病学特征及防控研究

  

  1. 1.100191 北京市,北京大学公共卫生学院
    2.100084 北京市,清华大学万科公共卫生与健康学院
  • 通讯作者: 刘民,梁万年
  • 基金资助:
    国家自然科学基金资助项目(71934002,72122001);首都卫生发展科研专项(2021-1G-4281)

Abstract:

Since the first case of the Omicron (B.1.1.529) variant discovered in South Africa was reported to the WHO on November 24, 2021, a total of 57 countries (regions) had reported Omicron cases as of December 8, 2021. Omicron has become the dominant strain in some African countries and is spreading rapidly. Although Omicron causes mild symptoms, with most cases being asymptomatic and mild, the rapid increase in the number of cases could put a heavy strain on global health systems. In addition, its source, transmission characteristics and vaccine resistance remain unclear, which brings great challenges to pandemic prevention and control in all countries (regions) . We reviewed the latest developments in etiological characteristics, mutation sources, transmission characteristics and possible mechanisms, pandemic status, vaccine protection effect and containment measures regarding Omicron, providing a reference for scientific containment of Omicron mutant.

Key words: SARS-CoV-2, Omicron variants of concern, COVID-19, Epidemiology, Review

摘要:

Omicron(B.1.1.529)变异株于2021年11月24日首次从南非报告给世界卫生组织,截至2021年12月8日全球共有57个国家和地区报告了Omicron感染病例。目前Omicron变异株在部分非洲国家已成为主导毒株,且传播速度快。尽管Omicron变异株引起的疾病症状较轻,多数病例为无症状感染者和轻型患者,但病例数量的快速增长可能给全球卫生系统带来沉重压力。此外,Omicron变异株的变异来源、传播特征、疫苗抗性等尚不明确,给各国和地区的疫情防控带来很大挑战。本文就Omicron变异株的病原学特征、变异来源、传播特征及可能的机制、流行现状、疫苗对其保护效果、防控措施等方面的研究进展进行综述,以期为科学防控Omicron变异株所致疫情提供参考。

关键词: 新型冠状病毒, Omicron关切变异株, 新型冠状病毒肺炎, 流行病学, 综述

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