Vitamin D Effectively Controls Gelastic Seizure of Non-epileptic：Report of One Case and Review of Literature

doi:10.12114/j.issn.1007-9572.2020.00.358

Abstract

Abstract: Clinical seizure events can be divided into epileptic seizure and non-epileptic seizure by whether epileptiform discharges appearing in VEEG or not at the same time of seizure，but non-epileptic seizures are easy to be misdiagnosed as epilepsy，leading to appropriate treatment.We reported a case of gelastic seizure of non-epileptic controlled by supplementing vitamin D，in which the patient's clinical features，treatment and prognosis were retrospectively analyzed and summarized，aiming to enhance the early diagnostic accuracy for this disease to reduce the possibilities of misdiagnosis and mistreatment by improving clinicians' recognition.We also suggest that clinicians should review the VEEG timely to further clarify the diagnosis when the clinical treatment effect of epilepsy is poor，by which serious mental burdens caused by inappropriate treatment on patients and their relatives may be avoided.

Key words: Epilepsy, Vitamin D, Nonepileptic seizure, Gelastic seizure

摘要： 临床发作性事件分为癫痫性发作和非癫痫性发作，通过视频脑电图可明确诊断，如果发作同期视频脑电图出现癫痫波即可诊断为癫痫性发作，否则可诊断为非癫痫性发作。而非癫痫性发作临床易误诊为癫痫，导致不合理的治疗。本文通过报道1例使用维生素D控制非癫痫性痴笑发作患者，回顾性分析并总结其临床特征、治疗及预后，旨在提高临床医师对该病的早期识别水平，以减少误诊、误治。同时也建议临床医师对于癫痫临床治疗效果欠佳时，应及时复查视频脑电图，进一步明确诊断，避免不合理的治疗给患者及其家属带来沉重的精神负担。

关键词: 癫痫, 维生素D, 非癫痫性发作, 痴笑发作

ZHANG Xiangmin,HAN Qian,LIU Zongyuan, et al. Vitamin D Effectively Controls Gelastic Seizure of Non-epileptic：Report of One Case and Review of Literature　[J]. Chinese General Practice, 2020, 23(30): 3856-3858. DOI: 10.12114/j.issn.1007-9572.2020.00.358.
张香敏,韩倩,刘宗源等. 维生素D有效控制非癫痫性痴笑发作一例报道并文献复习[J]. 中国全科医学, 2020, 23(30): 3856-3858. DOI: 10.12114/j.issn.1007-9572.2020.00.358.

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