Research Progress of Mechanism of Type D Personality on the Development of Coronary Heart Disease

doi:10.12114/j.issn.1007-9572.2019.00.735

Abstract

Abstract: As an important early warning indicator of coronary heart disease，more and more studies begin to pay attention to the mechanism and pathway between type D personality and the development of coronary heart disease.However，previous studies have only expounded the mechanism of type D personality on coronary heart disease from a single biomedical or behavioral psychology perspective，and no studies have clarified the mechanism from a complete perspective of biology and behavioral psychology.By summarizing the latest research evidence，this paper analyzes the relationship between type D personality and the occurrence，development and prognosis of coronary heart disease，and further explores the potential pathways between type D personality and coronary heart disease from the perspectives of biology and behavioral psychology to provide theoretical basis for clarifying the mechanism of type D personality on coronary heart disease.It provides new intervention targets for improving the clinical outcomes of patients with coronary heart disease and type D personality，so as to continuously improve the prognosis of patients with coronary heart disease，and prevent and reduce the occurrence of cardiac adverse events.

Key words: Type D personality, Coronary disease, Hypothalamo-hypophyseal system, Sympathetic nervous system, Mechanism, Review

摘要： D型人格作为冠心病发生发展的一个重要预警指标，越来越多的研究开始关注其与冠心病发生发展之间的作用机制及路径。然而，既往研究仅从单一的生物医学或行为心理学角度阐述D型人格对冠心病的作用机制，尚未有研究从完整的生物、心理及行为学层面阐明D型人格与冠心病发生发展之间的作用机制。本文通过综述最新研究证据，分析D型人格与冠心病发生发展及预后之间的关系，并从生物学及行为心理学角度进一步总结完善D型人格与冠心病之间可能的潜在作用路径，为明晰D型人格对冠心病的作用机制提供理论依据，从而为改善D型人格冠心病患者的临床结局提供新的干预靶点，不断提高冠心病患者预后，预防和减少心脏不良事件的发生。

关键词: D型人格, 冠心病, 下丘脑-垂体系统, 交感神经系统, 作用机制, 综述

YI Huijie,LIN Ping,LI Ling, et al. Research Progress of Mechanism of Type D Personality on the Development of Coronary Heart Disease　[J]. Chinese General Practice, 2020, 23(6): 737-741. DOI: 10.12114/j.issn.1007-9572.2019.00.735.
衣荟洁,林平,李玲等. D型人格对冠心病发生发展的作用机制研究进展[J]. 中国全科医学, 2020, 23(6): 737-741. DOI: 10.12114/j.issn.1007-9572.2019.00.735.

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