中国全科医学 ›› 2018, Vol. 21 ›› Issue (23): 2777-2780.DOI: 10.3969/j.issn.1007-9572.2018.00.145
• 专题研究 • 上一篇 下一篇
陈若冰，陈涛*
出版日期:
发布日期:
基金资助:
CHEN Ruo-bing，CHEN Tao*
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Online:
摘要： 肺癌是世界上最常见的恶性肿瘤，发病率和病死率高。非小细胞肺癌是最常见的肺癌组织类型，占80%~85%。目前肺癌的治疗以手术治疗联合放化疗为主，然而，手术治疗主要适用于Ⅰ期、Ⅱ期、特定的ⅢA期非小细胞肺癌患者，且5年总体生存率低于50%，所以寻找更安全、有效的治疗方法迫在眉睫。随着对肿瘤免疫学机制研究的深入，免疫治疗被提倡，在免疫治疗中，主要的方法是免疫抑制剂、疫苗治疗等，对特异的肿瘤相关抗原诱发特异性抗肿瘤免疫。本文主要对肺癌的疫苗治疗做一综述。
关键词: 肺肿瘤；癌, 非小细胞肺；癌症疫苗
Abstract: Lung cancer is the most common malignant tumor in the world with high incidence and mortality.As the most common type of lung cancer，non-small cell lung cancer accounts for 80%-85% of it.At present，the treatment of lung cancer is surgical treatment combined with radiotherapy and chemotherapy.However，surgical treatment is mainly applicable to stage Ⅰ，Ⅱ，and specific stage ⅢA non-small cell lung cancer，while its 5-year overall survival rate is less than 50%.Therefore，it is extremely urgent to find safer and more effective treatments.With the research of immunological mechanism of tumors，immunotherapy has been advocated and the main methods are immunosuppressants，vaccine therapy，which induces specific anti-tumor immunity against specific tumor-associated antigens.This article mainly reviews the vaccine treatment of lung cancer.
Key words: Lung neoplasms；Carcinoma, non-small-cell lung；Cancer vaccines
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链接本文: https://www.chinagp.net/CN/10.3969/j.issn.1007-9572.2018.00.145
https://www.chinagp.net/CN/Y2018/V21/I23/2777
