肛周Paget's病临床诊治进展

doi:10.12114/j.issn.1007-9572.2020.00.050

摘要/Abstract

摘要： 肛周Paget's病是一种罕见的恶性疾病，其临床表现不典型，易与肛周慢性湿疹、鲍温病等相混淆，且在临床诊断、治疗、复发因素及预后判断等方面尚无统一标准与共识，临床上误诊率较高。为此本文从流行病学、分类及发病机制、临床表现、诊断依据、鉴别诊断、治疗手段及复发和预后方面对肛周Paget's病做一综述，以提高临床医师对该病的认识。

关键词: 佩吉特病, 乳腺外；肛周Paget's病；病理学；诊断, 鉴别；治疗；预后

Abstract: Perianal Paget's disease is a rare malignant disease.Due to its atypical clinical manifestations，the disease is easily confused with chronic perianal eczema，abalone and other diseases，and there is no unified standard and consensus in clinical diagnosis，treatment，recurrence factors and prognosis judgment，so the misdiagnosis rate in clinical practice is high.Therefore，this paper will make a review of perianal Paget's disease from the aspects of epidemiology，classification，pathological features，clinical manifestations，differential diagnosis，treatment，recurrence and prognosis，so as to improve the clinicians' understanding of this disease.

Key words: Paget disease, extramammary；Paget's disease of perianal；Pathology；Diagnosis；Differential；Therapy；Prognosis

颜桂林,杜媛芳,蒲永平,等. 肛周Paget's病临床诊治进展[J]. 中国全科医学, 2020, 23(27): 3496-3502. DOI: 10.12114/j.issn.1007-9572.2020.00.050.
YAN Guilin,DU Yuanfang,PU Yongping, et al. Clinical Diagnosis and Treatment of Perianal Paget's Disease　[J]. Chinese General Practice, 2020, 23(27): 3496-3502. DOI: 10.12114/j.issn.1007-9572.2020.00.050.

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