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    Assessment and Treatment of Early-onset Hypertension: Position Statement of the British and Irish Hypertension Association and Its Implications for Clinical Management of Early-onset Hypertension in China
    BAI Jiaxin, CHEN Yu, ZHOU Yiheng, LIU Lidi, YANG Rong, YAO Yi, YUAN Bo, ZHANG Yonggang, LEI Yi, ZENG Rui, JIA Yu, LIAO Xiaoyang
    Chinese General Practice    2025, 28 (30): 3741-3746.   DOI: 10.12114/j.issn.1007-9572.2024.0406
    Abstract679)   HTML5)    PDF(pc) (1072KB)(72)       Save

    Hypertension is a global health issue that is increasingly manifesting in younger populations. Early-onset hypertension (≤40 years old) presents with complex underlying pathological mechanisms, challenging diagnoses of secondary causes, ambiguous timing for treatment initiation, and unclear management paradigms throughout the entire process. To address these issues, the British and Irish Hypertension Society (BIHS) issued a position statement in 2024 titled Assessment and Management of Early-onset Hypertension which provides guidance for standardizing the clinical management process of early-onset hypertension. Given the current absence of management documents suitable for early-onset hypertension in our country, this article organizes a team of clinicians from general practice and cardiovascular medicine to interpret the statement. The aim is to provide a reference for the management of early-onset hypertension in our country and to lay the groundwork for the development of documents tailored to our national conditions.

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    Interpretation and Clinical Implications of the 2024 Italian Guidelines for the Management of Adult Individuals with Overweight and Obesity and Metabolic Comorbidities That are Resistant to Behavioral Treatment
    ZHANG Peng, LIU Lidi, ZHANG Ying, YANG Ziyu, LIU Changming, TANG Yijun, LIAO Xiaoyang, JIA Yu
    Chinese General Practice    2025, 28 (30): 3747-3752.   DOI: 10.12114/j.issn.1007-9572.2025.0131
    Abstract275)   HTML6)    PDF(pc) (1099KB)(65)       Save

    Obesity is frequently accompanied by metabolism-related diseases, serving as a critical etiological factor or risk factor and being associated with adverse clinical outcomes. Effective weight reduction has been demonstrated to ameliorate or even alleviate these comorbidities. However, lifestyle interventions alone often yield suboptimal efficacy, and behavioral resistance is often observed. In China, there are currently no specific guidelines targeting patients with behavioral resistance. In 2024, the Italian Association of Clinical Endocrinologists released the Guidelines for the Management of Adult Individuals with Overweight and Obesity and Metabolic Comorbidities that are Resistant to Behavioral Treatment, grounded in the latest evidence-based research. The guidelines primarily focus on pharmacological and surgical interventions in this patient population. This paper, in conjunction with Chinese guidelines, delves into the obesity evaluation and treatment strategies from the Italian guidelines, aiming to offer a reference for managing Chinese overweight or obese patients with behavioral resistance.

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