Chinese General Practice ›› 2023, Vol. 26 ›› Issue (26): 3303-3307.DOI: 10.12114/j.issn.1007-9572.2023.0093
• Original Research • Previous Articles Next Articles
Received:
2023-02-20
Revised:
2023-03-03
Published:
2023-09-15
Online:
2023-03-09
Contact:
DANG Yi
通讯作者:
党懿
作者简介:
基金资助:
Add to citation manager EndNote|Ris|BibTeX
URL: https://www.chinagp.net/EN/10.12114/j.issn.1007-9572.2023.0093
组别 | 例数 | 性别(男/女) | 年龄(岁) | BMI〔M(P25,P75),kg/m2〕 | 家族史〔例(%)〕 | 吸烟史〔例(%)〕 | 高血压史〔例(%)〕 | 心房颤动史〔例(%)〕 | 糖尿病史〔例(%)〕 |
---|---|---|---|---|---|---|---|---|---|
无TCFA组 | 117 | 104/13 | 52.4±14.8 | 25.4(23.5,27.4) | 18(15.4) | 67(57.3) | 55(47.0) | 5(4.3) | 24(20.5) |
TCFA组 | 25 | 24/1 | 51.4±13.2 | 25.4(23.8,25.6) | 4(16.0) | 15(60.0) | 13(52.0) | 0 | 10(40.0) |
检验统计量值 | 0.508 | 0.339a | -0.482b | 0.006 | 0.063 | 0.206 | 0.207 | 4.295 | |
P值 | 0.476 | 0.735 | 0.630 | 0.938 | 0.802 | 0.650 | 0.586 | 0.038 | |
组别 | 高脂血症史〔例(%)〕 | 脑血管病史〔例(%)〕 | 术前收缩压〔M(P25,P75),mmHg〕 | 术前舒张压〔M(P25,P75),mmHg〕 | 心率〔M(P25,P75),次/min〕 | LVEF〔M(P25,P75),%〕 | TIMI血流分级〔例(%)〕 | ||
0~1级 | 2~3级 | ||||||||
无TCFA组 | 23(19.7) | 16(13.7) | 131(119,144) | 84(74,93) | 72(65,80) | 61.00(55.00,65.00) | 31(26.5) | 86(73.5) | |
TCFA组 | 7(28.0) | 5(20.0) | 130(122,144) | 80(72,97) | 70(61,81) | 58.00(53.50,61.00) | 8(32.0) | 17(68.0) | |
检验统计量值 | 0.860 | 0.248 | 0.107b | -0.453b | -0.525b | -1.488b | 0.313 | ||
P值 | 0.354 | 0.618 | 0.915 | 0.651 | 0.599 | 0.137 | 0.576 | ||
组别 | 心功能Killip分级〔例(%)〕 | 白细胞计数〔M(P25,P75),×109/L〕 | 中性粒细胞计数〔M(P25,P75),×109/L〕 | 淋巴细胞计数〔M(P25,P75),×109/L〕 | 空腹血糖〔M(P25,P75),mmol/L〕 | GFR〔M(P25,P75),mL·min-1·(1.73 m2)-1〕 | |||
Ⅰ级 | Ⅱ~Ⅳ级 | ||||||||
无TCFA组 | 91(77.8) | 26(22.2) | 8.30(6.24,10.71) | 5.28(3.96,8.12) | 1.70(1.28,2.36) | 5.54(4.77,6.63) | 98.30(88.00,107.94) | ||
TCFA组 | 16(64.0) | 9(36.0) | 9.06(6.34,10.82) | 5.84(4.30,9.11) | 1.67(1.15,2.08) | 5.68(4.80,7.66) | 101.87(96.57,112.07) | ||
检验统计量值 | 2.105 | 0.653b | 0.916b | -0.774b | 1.026b | 1.232b | |||
P值 | 0.147 | 0.513 | 0.360 | 0.439 | 0.305 | 0.218 | |||
组别 | 脂蛋白a〔M(P25,P75),mg/L〕 | TC(mmol/L) | TG〔M(P25,P75),mmol/L〕 | HDL-C〔M(P25,P75),mmol/L〕 | LDL-C〔M(P25,P75),mmol/L〕 | RC〔M(P25,P75),mmol/L〕 | |||
无TCFA组 | 172.50(94.55,327.30) | 4.24±1.19 | 1.36(0.98,2.18) | 0.98(0.87,1.17) | 2.78(2.01,3.26) | 0.38(0.24,0.59) | |||
TCFA组 | 218.20(126.45,378.95) | 4.66±1.45 | 1.82(1.00,2.95) | 0.98(0.92,1.14) | 3.00(2.26,3.72) | 0.58(0.44,0.82) | |||
检验统计量值 | 1.668b | -1.565a | 1.350b | -0.150b | 0.975b | 2.960b | |||
P值 | 0.095 | 0.120 | 0.177 | 0.881 | 0.330 | 0.003 |
Table 1 Comparison of baseline data between the two groups
组别 | 例数 | 性别(男/女) | 年龄(岁) | BMI〔M(P25,P75),kg/m2〕 | 家族史〔例(%)〕 | 吸烟史〔例(%)〕 | 高血压史〔例(%)〕 | 心房颤动史〔例(%)〕 | 糖尿病史〔例(%)〕 |
---|---|---|---|---|---|---|---|---|---|
无TCFA组 | 117 | 104/13 | 52.4±14.8 | 25.4(23.5,27.4) | 18(15.4) | 67(57.3) | 55(47.0) | 5(4.3) | 24(20.5) |
TCFA组 | 25 | 24/1 | 51.4±13.2 | 25.4(23.8,25.6) | 4(16.0) | 15(60.0) | 13(52.0) | 0 | 10(40.0) |
检验统计量值 | 0.508 | 0.339a | -0.482b | 0.006 | 0.063 | 0.206 | 0.207 | 4.295 | |
P值 | 0.476 | 0.735 | 0.630 | 0.938 | 0.802 | 0.650 | 0.586 | 0.038 | |
组别 | 高脂血症史〔例(%)〕 | 脑血管病史〔例(%)〕 | 术前收缩压〔M(P25,P75),mmHg〕 | 术前舒张压〔M(P25,P75),mmHg〕 | 心率〔M(P25,P75),次/min〕 | LVEF〔M(P25,P75),%〕 | TIMI血流分级〔例(%)〕 | ||
0~1级 | 2~3级 | ||||||||
无TCFA组 | 23(19.7) | 16(13.7) | 131(119,144) | 84(74,93) | 72(65,80) | 61.00(55.00,65.00) | 31(26.5) | 86(73.5) | |
TCFA组 | 7(28.0) | 5(20.0) | 130(122,144) | 80(72,97) | 70(61,81) | 58.00(53.50,61.00) | 8(32.0) | 17(68.0) | |
检验统计量值 | 0.860 | 0.248 | 0.107b | -0.453b | -0.525b | -1.488b | 0.313 | ||
P值 | 0.354 | 0.618 | 0.915 | 0.651 | 0.599 | 0.137 | 0.576 | ||
组别 | 心功能Killip分级〔例(%)〕 | 白细胞计数〔M(P25,P75),×109/L〕 | 中性粒细胞计数〔M(P25,P75),×109/L〕 | 淋巴细胞计数〔M(P25,P75),×109/L〕 | 空腹血糖〔M(P25,P75),mmol/L〕 | GFR〔M(P25,P75),mL·min-1·(1.73 m2)-1〕 | |||
Ⅰ级 | Ⅱ~Ⅳ级 | ||||||||
无TCFA组 | 91(77.8) | 26(22.2) | 8.30(6.24,10.71) | 5.28(3.96,8.12) | 1.70(1.28,2.36) | 5.54(4.77,6.63) | 98.30(88.00,107.94) | ||
TCFA组 | 16(64.0) | 9(36.0) | 9.06(6.34,10.82) | 5.84(4.30,9.11) | 1.67(1.15,2.08) | 5.68(4.80,7.66) | 101.87(96.57,112.07) | ||
检验统计量值 | 2.105 | 0.653b | 0.916b | -0.774b | 1.026b | 1.232b | |||
P值 | 0.147 | 0.513 | 0.360 | 0.439 | 0.305 | 0.218 | |||
组别 | 脂蛋白a〔M(P25,P75),mg/L〕 | TC(mmol/L) | TG〔M(P25,P75),mmol/L〕 | HDL-C〔M(P25,P75),mmol/L〕 | LDL-C〔M(P25,P75),mmol/L〕 | RC〔M(P25,P75),mmol/L〕 | |||
无TCFA组 | 172.50(94.55,327.30) | 4.24±1.19 | 1.36(0.98,2.18) | 0.98(0.87,1.17) | 2.78(2.01,3.26) | 0.38(0.24,0.59) | |||
TCFA组 | 218.20(126.45,378.95) | 4.66±1.45 | 1.82(1.00,2.95) | 0.98(0.92,1.14) | 3.00(2.26,3.72) | 0.58(0.44,0.82) | |||
检验统计量值 | 1.668b | -1.565a | 1.350b | -0.150b | 0.975b | 2.960b | |||
P值 | 0.095 | 0.120 | 0.177 | 0.881 | 0.330 | 0.003 |
自变量 | β | SE | Wald χ2值 | P值 | OR(95%CI) |
---|---|---|---|---|---|
年龄 | -0.014 | 0.018 | 0.603 | 0.437 | 0.986(0.951,1.022) |
家族史 | -0.137 | 0.669 | 0.042 | 0.837 | 0.872(0.235,3.233) |
吸烟史 | -0.046 | 0.493 | 0.009 | 0.926 | 0.955(0.363,2.513) |
高血压史 | 0.304 | 0.490 | 0.385 | 0.535 | 1.356(0.519,3.545) |
糖尿病史 | 0.662 | 0.512 | 1.671 | 0.196 | 1.939(0.710,2.513) |
高脂血症史 | -0.299 | 0.651 | 0.211 | 0.646 | 0.741(0.207,2.656) |
脂蛋白a | 0.002 | 0.001 | 2.942 | 0.086 | 1.002(1.000,1.003) |
HDL-C | -0.363 | 1.095 | 0.110 | 0.740 | 0.696(0.081,5.947) |
LDL-C | -0.041 | 0.278 | 0.022 | 0.883 | 0.960(0.557,1.654) |
RC | 1.657 | 0.754 | 4.820 | 0.028 | 5.241(1.195,22.995) |
Table 2 Multivariate Logistic regression analysis of factors influencing intracoronary TCFA in ACS patients
自变量 | β | SE | Wald χ2值 | P值 | OR(95%CI) |
---|---|---|---|---|---|
年龄 | -0.014 | 0.018 | 0.603 | 0.437 | 0.986(0.951,1.022) |
家族史 | -0.137 | 0.669 | 0.042 | 0.837 | 0.872(0.235,3.233) |
吸烟史 | -0.046 | 0.493 | 0.009 | 0.926 | 0.955(0.363,2.513) |
高血压史 | 0.304 | 0.490 | 0.385 | 0.535 | 1.356(0.519,3.545) |
糖尿病史 | 0.662 | 0.512 | 1.671 | 0.196 | 1.939(0.710,2.513) |
高脂血症史 | -0.299 | 0.651 | 0.211 | 0.646 | 0.741(0.207,2.656) |
脂蛋白a | 0.002 | 0.001 | 2.942 | 0.086 | 1.002(1.000,1.003) |
HDL-C | -0.363 | 1.095 | 0.110 | 0.740 | 0.696(0.081,5.947) |
LDL-C | -0.041 | 0.278 | 0.022 | 0.883 | 0.960(0.557,1.654) |
RC | 1.657 | 0.754 | 4.820 | 0.028 | 5.241(1.195,22.995) |
斑块特征 | rs值 | P值 |
---|---|---|
斑块破裂 | 0.213 | 0.011 |
TCFA | 0.249 | 0.003 |
管腔狭窄程度 | 0.142 | 0.092 |
参考管腔面积 | 0.030 | 0.732 |
最小管腔面积 | 0.061 | 0.467 |
血栓 | 0.041 | 0.627 |
微血管 | 0.136 | 0.106 |
钙化 | 0.148 | 0.079 |
巨噬细胞浸润 | 0.186 | 0.026 |
胆固醇结晶 | 0.138 | 0.100 |
Table 3 Spearman rank correlation analysis of RC and coronary plaque characteristics
斑块特征 | rs值 | P值 |
---|---|---|
斑块破裂 | 0.213 | 0.011 |
TCFA | 0.249 | 0.003 |
管腔狭窄程度 | 0.142 | 0.092 |
参考管腔面积 | 0.030 | 0.732 |
最小管腔面积 | 0.061 | 0.467 |
血栓 | 0.041 | 0.627 |
微血管 | 0.136 | 0.106 |
钙化 | 0.148 | 0.079 |
巨噬细胞浸润 | 0.186 | 0.026 |
胆固醇结晶 | 0.138 | 0.100 |
[1] |
|
[2] |
|
[3] |
|
[4] |
|
[5] |
|
[6] |
|
[7] |
|
[8] |
|
[9] |
|
[10] |
|
[11] |
|
[12] |
|
[13] |
|
[14] |
|
[15] |
|
[16] |
|
[17] |
|
[18] |
|
[19] |
|
[20] |
|
[21] |
|
[22] |
|
[23] |
|
[24] |
|
[25] |
|
[26] |
|
[1] | ZHANG Di, LI Hongpeng, MA Jiang, NIE Qian, SUN Jianfeng, WU Zhipeng, ZHANG Hongcai, ZHAO Jue. Effect of Ocular Acupuncture and Exercise Combination Therapy on Postoperative Heart Rate Variability and Prognosis of Patients Treated with Percutaneous Coronary Intervention [J]. Chinese General Practice, 2023, 26(36): 4535-4544. |
[2] | LAN Yonghao, KE Erqin, HAN Rui, MEI Yingchen, LIU Wei. Percutaneous Coronary Intervention via Distal Transradial Approach: Strengths, Weaknesses, Opportunities and Challenges [J]. Chinese General Practice, 2023, 26(27): 3355-3360. |
[3] | YUAN Mingpei, LIN Yaowang, BEI Weijie, LIU Huadong, DONG Shaohong, SUN Xin. Feasibility of Retrograde Recanalization of Occluded Radial Artery via Distal Transradial Artery Approach: a Single-center Prospective Study [J]. Chinese General Practice, 2023, 26(27): 3373-3377. |
[4] | CAI Gaojun, SHI Ganwei, LI Feng, LI Wenhua, YAN Yongmin, XUE Sheliang, XIAO Jianqiang, GU Jun, SONG Yanbin, ZHANG Liuyan, LU Wei, GONG Chun. How to Improve the Success Puncture Rate of Distal Transradial Artery Approach, "Winding Path to the Secluded": Summary of the Experience of More than 2 000 Cases [J]. Chinese General Practice, 2023, 26(27): 3361-3365. |
[5] | LIU Minghao, WANG Pan, GAO Lijian, XU Shuqing, WANG Huanhuan, ZHAO Guangxian, CHEN Jue, QIAO Shubin, XU Bo, YUAN Jinqing. Feasibility, Safety and Timing of Secondary Percutaneous Coronary Intervention via Distal Transradial Artery Approach [J]. Chinese General Practice, 2023, 26(27): 3366-3372. |
[6] | CHEN Yan, LYU Zhibo, ZHAO Xin. Correlation of Discordance between Remnant Lipoprotein Cholesterol and Non-high-density Lipoprotein Cholesterol and Severity of Coronary Stenosis [J]. Chinese General Practice, 2023, 26(24): 3010-3015. |
[7] | ZUMURETI ·Abudukeyimu, MA Yanlin, ZHU Kairui, LIU Fang, LI Xia. Correlation of Early Growth Response 3 and Interleukin 6 Expression Levels with Coronary Heart Disease [J]. Chinese General Practice, 2023, 26(24): 3016-3021. |
[8] | WANG Dan, WANG Jianhui, DONG Jianxiu, CHANG Wenhong, QIN Lu, LIU Qi, CHEN Chen. Effect of an Internet-based Intervention on Motor Behavior in Patients after Percutaneous Coronary Intervention [J]. Chinese General Practice, 2023, 26(21): 2603-2608. |
[9] | ZHOU Shiyu, CHEN Shaolin, DENG Renli, DAI Mi, LIU Tao, TIAN Kunming. The Association and Predictive Value of Lipid Ratios to Metabolic Syndrome: a Multistage Cross-sectional Study [J]. Chinese General Practice, 2023, 26(21): 2589-2596. |
[10] | WANG Zhou, DENG Jinlong, WU Dongfeng. Association between ACAT-1 rs1044925 SNP and Acute Coronary Syndrome and Change of Serum Lipid Level in Response to Atorvastatin Treatment [J]. Chinese General Practice, 2023, 26(21): 2620-2625. |
[11] | LIU Jingtao, SU He, QIN Xiaojin, LAN Yunxia, ZHANG Jinzhi. Guidelines on Cardiac Rehabilitation in Patients with Coronary Heart Disease: a Systematic Review [J]. Chinese General Practice, 2023, 26(19): 2323-2331. |
[12] | GAO Yang, WANG Yunxia, GAO Chuanyu. Familial Hypercholesterolemia in 45-year-old and Younger Patients with Acute Coronary Syndrome: Clinical Characteristics and Influencing Factors of Blood Lipid Control Effect [J]. Chinese General Practice, 2023, 26(18): 2232-2237. |
[13] | LIU Chuanfen, LI Zheng, WU Manyan, CUI Yuxia, SONG Jing, ZHANG Chunying, CHEN Hong. Analysis of Serum Lipid Level and Drug Use in Patients with Acute Myocardial Infarction [J]. Chinese General Practice, 2023, 26(11): 1325-1329. |
[14] | AN Jingjing, WANG Xiaojuan, DENG Aiyun. Effect of Epicardial Adipose Tissue on In-stent Restenosis after Percutaneous Coronary Intervention: a Review [J]. Chinese General Practice, 2023, 26(09): 1146-1150. |
[15] | DENG Tianhua, HUANG Lin, YOU Zhigang. Advances in Intensified Antithrombotic Therapies in Acute Coronary Syndrome [J]. Chinese General Practice, 2023, 26(09): 1131-1135. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||