Abstract: Cerebral hemorrhage and visceral hemorrhage are the most serious complications of primary immune thrombocytopenia （ITP），which are commonly seen in hematonosis patients，with extremely high mortality.We reported the clinical diagnosis and treatment of one case of ITP with multiple intracranial hemorrhages.The patient had been diagnosed with thrombocytopenic purpura for more than 20 years.During this period，she had suffered from 3 times of intracerebral hemorrhage involving multiple compartments and one time of gastrointestinal hemorrhage.As the amount of bleeding was not large，she has good survival，which is rarely seen clinically and may be related to the actions of other hemostatic mechanisms.Moreover，on the basis of the reviewing of related studies，we found some effective prevention and treatment measures for ITP，in order to offer some assistance for clinicians.

Key words: Thrombocytopenia, Intracranial hemorrhage, Mechanism, Treatment outcome

摘要： 原发免疫性血小板减少症（ITP）最严重的并发症是脑出血和内脏出血，是血液病常见的并发症，病死率极高。本文报道了1例ITP并发多次颅内出血患者的临床诊疗经过，该患者确诊血小板减少性紫癜20余年，期间3次颅内出血，而且是颅内多部位出血，1次消化道出血，均出血量不大，未引起患者死亡，临床极其罕见，显示可能有其他的止血机制发挥作用，因此笔者结合文献复习，以期寻找到ITP患者脑出血的有效预防及治疗措施，为临床提供帮助。

关键词: 血小板减少, 颅内出血, 机制, 治疗结果