Stroke hand dysfunction seriously affects the quality of life of patients. In recent years, studies of robot-assisted training for functional recovery of stroke patients has gradually increased, but the improvement effect lacks effective systematic evaluation and analysis, and assist specific training programs still needs to be further explored.

To systematically evaluate the intervention effect of rehabilitation robot-assisted training on the hand motor function in stroke patients.

Randomized controlled trials of rehabilitation robot-assisted training for hand motor function in stroke patients were searched in PubMed, Embase, Scopus, Cochrane Library, Web of Science, CNKI, Wanfang Data, VIP and SinoMed, the time limit for searching was from the establishment of each database to December 2023. Literature screening, extraction of raw data and evaluation of the methodological quality of the literature were carried out in strict accordance with the inclusion and exclusion criteria. Meta-analysis was performed using RevMan 5.4 and Stata 17.0.

A total of 23 studies and 693 stroke patients were included in the literature. The results of meta-analysis showed that the experimental group's Fugl-Meyer Motor Function Assessment-Upper Limb(FMA-UL) (SMD=0.37, 95%CI=0.17-0.58, P<0.001), FMA-UL of wrist (MD=1.66, 95%CI=0.14-3.17, P=0.03) and hand portion (MD=2.00, 95%CI=1.17-2.83, P<0.001), Upper Extremity Movement Study Scale (SMD=0.27, 95%CI=0.01-0.53, P=0.04), handgrip strength (SMD=0.54, 95%CI=0.09-1.00, P=0.02), and hand pinch (SMD=0.62, 95%CI=0.16-1.09, P=0.008) scores improved better than those of the control group, there were significant differences between two groups. There were no significant differences in Block-Box Test (MD=1.23, 95%CI=-0.90 to 3.35, P=0.26), Modified Ashworth Scale (SMD=-0.47, 95%CI=-1.28 to 0.35, P=0.26), and Barthel Index (SMD=0.38, 95%CI=-0.07 to 0.83, P=0.10) scores.

Rehabilitation robot-assisted training is beneficial to the recovery of hand motor function in stroke patients, which can effectively improve hand mobility, grip and pinch ability, but the improvement in hand tone, dexterity and daily living ability scores is relatively small. Future studies with large samples, multi-center, and longer follow-up periods are needed to further evaluate its efficacy and safety.

脑卒中手功能障碍严重影响患者的生活质量，近年来，机器人辅助训练用于脑卒中患者手功能恢复的研究逐渐增加，但改善效果缺乏有效的系统评价与分析，辅助训练具体方案仍需要进一步探讨。

系统评价康复机器人辅助训练对脑卒中患者手运动功能的恢复效果。

计算机检索PubMed、Embase、Scopus、Cochrane Library、Web of Science、中国知网（CNKI）、万方数据知识服务平台、维普网（VIP）和中国生物医学文献服务系统（SinoMed）中采用机器人辅助训练干预脑卒中患者手功能恢复的随机对照研究，检索时限为建库至2023年12月。严格按照纳排标准进行文献筛选，提取原始数据，对纳入文献进行方法学质量评价，使用RevMan 5.4和Stata 17.0软件进行Meta分析。

共纳入文献23篇，693例脑卒中患者。Meta分析结果显示，试验组上肢运动功能评定量表（FMA-UL）（SMD=0.37，95%CI=0.17~0.58，P<0.001）、手腕FMA-UL（MD=1.66，95%CI=0.14~3.17，P=0.03）、手FMA-UL（MD=2.00，95%CI=1.17~2.83，P<0.001）、上肢动作研究量表（SMD=0.27，95%CI=0.01~0.53，P=0.04）、手握力（SMD=0.54，95%CI=0.09~1.00，P=0.02）、手捏力（SMD=0.62，95%CI=0.16~1.09，P=0.008）评分均高于对照组；两组间积木-箱子测验（MD=1.23，95%CI=-0.90~3.35，P=0.26）、改良Ashworth量表（SMD=-0.47，95%CI=-1.28~0.35，P=0.26）、Barthel指数（SMD=0.38，95%CI=-0.07~0.83，P=0.10）评分比较，差异均无统计学意义。

康复机器人辅助训练有利于脑卒中患者手运动功能的恢复，能有效提高脑卒中患者手部活动能力、握捏能力，但在手部肌张力、灵活度与日常生活能力评分方面改善较小。未来需要大样本、多中心、更长随访期的研究来进一步评估其疗效和安全性。