Abstract: Background　Available studies mainly focus on the epidemiological indicators of diabetes，but inadequately evaluate the prevention and treatment effect for diabetes as well as its prevalence using a time-trend analysis.Moreover，there is few studies about age-specific prevalence and risk factors of impaired fasting glucose（IFG）.Objective　To analyze age-specific prevalence and risk factors of IFG and the development trend in Zhenjiang City from 2011 to 2017 using the chronic disease surveillance data.Methods　This study was conducted from June 2011 to December 2017.We retrospectively analyzed the chronic disease surveillance data from 2011 to 2017 of Zhenjiang City，which were obtained via questionnaire survey，physical examination and laboratory examination.Age-specific and standardized prevalence as well as risk factors of IFG and their trend during the period were analyzed.Results　A total of 29 400 testees to the questionnaire were extracted，and 130 of them（0.46%）were excluded，other 28 408 cases（96.63%）were finally enrolled，including 3 953，3 482，4 259，4 270，4 203，4 039，and 4 202 cases for 2011，2012，2013，2014，2015，2016，and 2017，respectively.The prevalence of IFG showed a downward trend in male residents aged 45-59 from 2011 to 2017〔annual percent change（APC）=-6.92，95%CI（-12.50，-1.00），P<0.05〕，as well as in male residents aged 60 or over from 2014 to 2017〔APC=-15.71，95%CI（-26.50，-3.30），P<0.05〕.The overall standardized prevalence of IFG showed a downward trend in all of the residents〔APC=-3.18，95%CI（-5.90，-0.40），P<0.05〕，as well as in all of the male residents〔APC=-5.26，95%CI（-9.50，-0.80），P<0.05〕. The standardized prevalence of IFG also showed a downward trend in male residents aged 60 or over from 2014 to 2017〔APC=-16.23，95%CI（-28.20，-2.30），P<0.05〕.During 2011 to 2017，there were no significant differences in prevalence rates of smoking and passive smoking，as well as vegetable intake frequency at least 4 days per week（P>0.05）.The prevalence rates of drinking，good and very good sleep quality，basically unchanged body weight within the year prior to the survey，overweight，systolic blood pressure less than 130 mm Hg，and diastolic blood pressure less than 85 mm Hg，having breakfast at least 5 days per week，having fruits at least 4 days per week showed an upward trend（P<0.05），while those of time spending in specific sedentary behaviors less than 4 hours per day，obesity and central obesity showed a downward trend（P<0.05）.The prevalence rate of IFG related risk factors showed significant differences in different age groups.Conclusion　The prevalence and risk factors of IFG were partly under control in Zhenjiang City from 2011 to 2017，especially in male residents aged 60 or over，indicating that the community interventions for IFG have obtained initial achievements.In the delivery of related interventions further，priority should be given to young and middle-aged people，and the interventions should be changed timely by age group，IFG prevalence and risk factors at a point of time .

Key words: Diabetes mellitus, Blood glucose, Impaired fasting blood glucose, Time-trend analysis, Risk factors, Age groups, Community-based participatory research

摘要： 背景　现有研究主要集中于糖尿病相关指标流行率，对防治效果的评价和患病率的时间变化趋势分析不足，且关于不同年龄段居民空腹血糖受损（IFG）情况及其相关危险因素流行趋势的研究报道较少。目的　基于2011—2017年镇江市慢性病监测数据分析不同年龄段人群IFG情况及其时间变化趋势、相关危险因素流行趋势。方法　本研究实施时间为2011年6月—2017年12月。回顾性分析2011—2017年镇江市历年慢性病及其危险因素监测数据，该监测主要通过问卷调查、体格检查与实验室检查相结合的方式开展。分析不同年龄段居民IFG率、标化IFG率时间变化趋势及IFG相关危险因素流行趋势。结果　共发放调查问卷29 400份，回收有效问卷28 408份，有效回收率为96.63%；共130名居民被置换，置换率为0.46%；2011—2017年分别抽取到3 953、3 482、4 259、4 270、4 203、4 039、4 202名居民。2011—2017年45~59岁男性居民IFG率呈下降趋势〔年度变化百分比（APC）=-6.92，95%CI（-12.50，-1.00），P<0.05〕；2014—2017年≥60岁男性居民IFG率亦呈下降趋势〔APC=-15.71，95%CI（-26.50，-3.30），P<0.05〕。2011—2017年所有居民总体标化IFG率呈下降趋势〔APC=-3.18，95%CI（-5.90，-0.40），P<0.05〕，男性居民总体标化IFG率亦呈下降趋势〔APC=-5.26，95%CI（-9.50，-0.80），P<0.05〕；2014—2017年≥60岁男性居民标化IFG率呈下降趋势〔APC=-16.23，95%CI（-28.20，-2.30），P<0.05〕。2011—2017年所有居民吸烟、被动吸烟、蔬菜摄入频次≥4 d/周流行率变化趋势均无统计学意义（P>0.05）；饮酒、早餐摄入频次≥5 d/周、水果摄入频次≥4 d/周、睡眠质量好及很好、近1年内体质量基本不变、超重、血压<130/85 mm Hg流行率呈上升趋势（P<0.05），静态行为时间<4 h/d、肥胖、中心性肥胖流行率呈下降趋势（P<0.05）。不同年龄段居民IFG相关危险因素流行率呈现不同变化趋势。结论　2011—2017年镇江市居民IFG及其相关危险因素流行趋势均得到了一定控制，尤其是在2014—2017年≥60岁的男性居民中，社区IFG相关干预工作初显成效，今后应注意加大对中青年人群的干预力度，并根据年龄别IFG率时间变化趋势及相关危险因素流行趋势适时调整工作重点。

关键词: 糖尿病, 血糖, 空腹血糖受损, 时间趋势分析, 危险因素, 年龄组, 社区参与研究