Research Progress on Biomarkers in Early Diagnosis of Pediatric Cerebral Palsy

doi:10.12114/j.issn.1007-9572.2019.00.513

Abstract

Abstract: Pediatric cerebral palsy is a non-progressive brain injury syndrome，which generally occurs in the brain development stage from prenatal period to postnatal period and presents a group of syndromes mainly involving postural and motor dysfunction.Cerebral palsy is characterized by high morbidity，mortality and disability rate.It has become an urgent child health problem which seriously threatens the growth and development of children with a huge burden to families and society and needs to be solved in recent years.Therefore，the early identification and diagnosis of pediatric cerebral palsy plays an important role in its early rehabilitation intervention and effect and the reduction of disability in children with cerebral palsy.This paper reviews the research progress of biomarkers related to the early diagnosis of pediatric cerebral palsy in order to provide a reference for the early diagnosis of cerebral palsy in children.

Key words: Cerebral palsy, Early diagnosis, Biochemical indices, Review

摘要： 小儿脑性瘫痪（CP）是一种非进行性脑损伤综合征，一般发生于出生前至出生后脑发育阶段，表现为一组以姿势及运动功能障碍为主的症候群。CP具有发病率高、致残率高和死亡率高的特点，其已成为近年来亟待解决的儿童健康问题，该病严重威胁患儿的生长发育，也给家庭、社会带来了巨大的负担。因此早期识别和诊断对CP患儿进行早期康复干预、提高康复疗效，减少患儿残障具有非常重要的作用。本文就小儿CP早期诊断相关生化指标研究进展做一综述，为小儿CP的早期诊断提供参考。

关键词: 脑性瘫痪, 早期诊断, 生化指标, 综述

WANG Jing,LIU Yun,DENG Xiaoli, et al. Research Progress on Biomarkers in Early Diagnosis of Pediatric Cerebral Palsy[J]. Chinese General Practice, 2020, 23(8): 1003-1008. DOI: 10.12114/j.issn.1007-9572.2019.00.513.
王静,刘芸,邓晓莉等. 小儿脑性瘫痪早期诊断中生化指标的研究进展[J]. 中国全科医学, 2020, 23(8): 1003-1008. DOI: 10.12114/j.issn.1007-9572.2019.00.513.

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