Abstract: Background　There are few epidemiological studies on the disease spectrum，cause of death and discharge prognosis of hospitalized patients in emergency centers.Therefore，it is important to take a large scale epidemiological survey in emergency centers to understand epidemiological feature，which is of great significance for early detection of patients and high-risk groups and comprehensive prevention and control.Objective　To evaluate the epidemiological distribution of inpatients in emergency centers over the ten years，to explore the influencing factors of prognosis，and to provide clinical evidence for improving quality and safety of diagnosis and treatment in emergency centers.Methods　The demographic characteristics and disease status of inpatients in the Emergency Center of the First Affiliated Hospital of Xinjiang Medical University from 2007 to 2016 were retrieved by hospital information system （HIS），including gender，age，allergy history，length of stay，admission department，discharge department，hospitalization expenses，number of re-admissions within 30 days，number of operations，first hospitalization diagnosis，combined disease and prognosis.Multivariate Logistic regression analysis was used to assess factors influencing prognosis of inpatients in emergency center by SPSS 19.0 statistical software.Results　A total of 16 367 inpatients were hospitalized in emergency centers from 2007 to 2016，15 686 （95.84%） survived and 681 （4.16%） died.The number of inpatients in emergency center in 2016 was 45.59% higher than that in 2007.The results of multivariate Logistic regression analysis revealed that the age 〔OR=1.326，95%CI（1.067，1.648）〕，admission department 〔OR=0.668，95%CI（0.564，0.790）〕，discharge department 〔OR=1.608，95%CI（1.309，1.975）〕，hospitalization expenses 〔OR=3.589，95%CI（2.826，4.559）〕，30-day unplanned readmission 〔OR=4.527，95%CI（1.023，5.183）〕，operation frequency 〔OR=3.353，95%CI（2.901，3.877）〕，mental disorder 〔OR=2.988，95%CI（1.047，8.530）〕，heart disease 〔OR=13.146，95%CI（3.647，47.371）〕，hypertension 〔OR=0.518，95%CI（0.258，0.941）〕，recovery period of cerebrovascular accident 〔OR=1.805，95%CI（1.091，2.989）〕，liver disease 〔OR=1.938，95%CI（1.230，3.056）〕，chronic poisoning 〔OR=2.162，95%CI（1.261，3.691）〕，and concomitant diseases 〔OR=2.322，95%CI（1.270，4.250）〕 had regression relationships with the prognosis of inpatients in emergency center （P<0.05）.Conclusion　The number of patients in emergency center is increasing year by year，and the quality and safety of diagnosis and treatment also attract attention.Age，unit of admission and discharge，hospitalization expenses，the number of operation，30-day unplanned readmission，and combined diseases are independent prognostic factors，influencing survival of inpatient in emergency center.Therefore，we should improve emergency mode and intervene preventable factors to improve the quality and safety of inpatient diagnosis and treatment in emergency centers.

Key words: Emergency service, hospital；Inpatients；Prognosis；Root cause analysis

摘要： 背景　目前对急救中心住院患者疾病谱、死因谱、出院预后相关的流行病学研究较少。因此，在急救中心范围内进行一次较大规模的流行病学调查，全面了解急救中心住院患者目前流行病学特征，对于早期发现高危人群以及综合防控具有重要意义。目的　分析急救中心近10年住院患者流行病学特点，探讨预后影响因素，为提高急救中心诊疗质量与安全提供临床证据。方法　利用医院信息化管理系统（HIS）检索2007—2016年新疆医科大学第一附属医院急救中心住院患者的人口学特征和疾病状况，包括性别、年龄、过敏史、住院天数、入院科室、出院科室、住院费用、30 d内再入院次数、手术次数、首次住院诊断、合并疾病及预后。采用SPSS 19.0统计学软件多因素Logistic回归分析急救中心住院患者预后的影响因素。结果　2007—2016年急救中心住院患者共计16 367例，生存15 686例（95.84%），死亡681例（4.16%）。2016年急救中心住院患者较2007年环比增长45.59%。多因素Logistic回归分析结果显示：年龄〔OR=1.326，95%CI（1.067，1.648）〕、入院科室〔OR=0.668，95%CI（0.564，0.790）〕、出院科室〔OR=1.608，95%CI（1.309，1.975）〕、住院费用〔OR=3.589，95%CI（2.826，4.559）〕、30 d内再入院次数〔OR=4.527，95%CI（1.023，5.183）〕、手术次数〔OR=3.353，95%CI（2.901，3.877）〕、合并心理障碍〔OR=2.988，95%CI（1.047，8.530）〕、心脏病〔OR=13.146，95%CI（3.647，47.371）〕、高血压〔OR=0.518，95%CI（0.258，0.941）〕、脑血管意外恢复期〔OR=1.805，95%CI（1.091，2.989）〕、肝脏疾病〔OR=1.938，95%CI（1.230，3.056）〕、慢性中毒〔OR=2.162，95%CI（1.261，3.691）〕、多种疾病〔OR=2.322，95%CI（1.270，4.250）〕与急救中心住院患者预后有回归关系（P<0.05）。结论　急救中心诊疗患者逐年增多，诊疗质量及安全也引起重视，年龄、入院科室、出院科室、住院费用、30 d内再次入院次数、手术次数、合并疾病是急救中心住院患者预后的独立影响因素，因此完善急救模式，干预可预防因素来提高急救中心住院诊疗质量与安全。

关键词: 急诊室, 医院；住院病人；预后；影响因素分析