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Guideline on Treating Adult Community-acquired Pneumonia with Chinese Patent Medicines(2025 Edition)

  

  1. 1.National Regional TCM(Lung Disease) Diagnostic and Treatment Center,The First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou 450000,China;2.Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases Co-constructed by Henan Province & Education Ministry of P.R. China,Zhengzhou 450046,China;3.China Evidence-Based Medicine Center,Lanzhou University,Lanzhou 730030,China;4.Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology,Wuhan 430030,China;5.Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing 100061,China;6.Cochrane China Center,West China Hospital,Sichuan University,Chengdu 610041,China
  • Received:2025-03-27 Revised:2025-04-13 Accepted:2025-04-14
  • Contact: LI Suyun,Chief physician/Doctoral supervisor;E-mail:lisuyun2000@126.com  WANG Minghang,Chief physician/Doctoral supervisor;E-mail:wmh107hn@163.com

中成药治疗成人社区获得性肺炎临床应用指南(2025 版)

  

  1. 1.450000 河南省郑州市,河南中医药大学第一附属医院 国家区域中医(肺病)诊疗中心;2.450046 河南省郑州市,河南中医药大学 呼吸疾病中医药防治省部共建协同创新中心;3.730030 甘肃省兰州市,兰州大学循证医学中心;4.430030 湖北省武汉市,华中科技大学同济医学院附属同济医院;5.100061 北京市,中国中医科学院西苑医院;6.610041 四川省成都市,四川大学华西医院中国 Cochrane 中心
  • 通讯作者: 李素云,主任医师 / 博士生导师;E-mail:lisuyun2000@126.com  王明航,主任医师 / 博士生导师;E-mail:wmh107hn@163.com
  • 基金资助:
    国家重点研发计划“中医药现代化研究”重点专项(2023YFC3502602);国家中医药管理局中成药治疗优势病种标准化项目(SATCM-2015-BZ402-407);国家自然科学基金面上项目(82474483)

Abstract: Community-acquired pneumonia(CAP),one of the most common infectious diseases,exhibits increasing morbidity and mortality with age,posing significant clinical challenges. Although Chinese patent medicines(CPMs)demonstrate efficacy in adult CAP treatment,high-quality evidence-based guidelines have been lacking. To address this gap,we organized a multidisciplinary expert panel to develop the guideline on treating adult community-acquired pneumonia with Chinese patent medicines(2022 Edition),adhering to the principles of evidence-based,consensus-supplemented,and experience-referred and following standardized clinical practice guideline development procedures. Through literature review and Delphi questionnaires,six clinical questions were identified. Systematic evidence retrieval and synthesis of the best available evidence were conducted,integrating factors such as evidence quality,patient preferences,value orientations,and resource allocation. After two rounds of Delphi surveys and expert consensus meetings,the guideline was finalized and published in 2023 in Pharmacological Research. This updated edition systematically incorporates recent evidence,adds pharmacoeconomic evaluations and recommendation rationales,and presents 14 recommendations covering nine CPMs,covers 9 kinds of traditional Chinese patent medicines. The guideline has been restructured according to the first edition of reporting checklist for Chinese patent medicine guidelines(RIGHT for CPM) to enhance clinical applicability,accessibility,and operationalizability,thereby promoting the rational use of CPMs in adult CAP treatment.

Key words: Community-acquired pneumonia, Chinese patent medicines, Therapy, Adult, Guideline

摘要: 社区获得性肺炎(CAP)是常见的感染性疾病之一,其发病率和病死率随年龄增长而上升,当前治疗面临诸多挑战。中成药治疗成人CAP疗效明确,但缺乏高质量循证指南。为此,课题组组织多学科专家,遵循“循证为主、共识为辅、经验为鉴”原则,参照临床实践指南研制规范,通过文献调研、德尔菲法问卷遴选出6个临床问题,系统检索并整合当前最佳循证证据。在综合评估证据质量、患者意愿、价值取向及资源配置等因素的基础上,通过两轮德尔菲调研及专家共识会议,最终形成《中成药治疗成人社区获得性肺炎临床应用指南(2022版)》,于2023年发表在Pharmacological Research。本次修订对证据进行了系统更新,新增药物经济性及推荐理由,共形成14条推荐意见,涵盖9种中成药,并依据首部中成药临床实践指南报告规范完成改编,以提升指南临床适用性、可及性及可操作性,促进中成药在成人CAP治疗中的合理使用。

关键词: 社区获得性肺炎, 中成药, 治疗, 成人, 指南

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