Chinese General Practice

Special Issue: 生活方式干预相关研究最新文章合集

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The Impact of Behavioral Lifestyle on Quality of Life in Hypertensive Patients

  

  1. 1.Department of Pharmacy,The Fifth Affiliated Hospital of Sun Yat-sat University,Zhuhai 519000,China;2.School of Medical Humanities,China Medical University,Shenyang 110122,China;3.School of Traditional Chinese Medicine,Beijing University of Chinese Medicine,Beijing 120488,China;4.Department of Preventive Medicine,Yanjing Medical College,Capital Medical University,Beijing 101300,China;5.Beijing Chaoyang District Center for Disease Control and Prevention,Beijing 100021,China;6.School of Public Health,Hainan Medical University,Haikou 571199,China;7.School of Public Health,Peking University,Beijing 100191,China;8.Department of Pharmacy,Linyi People's Hospital,Linyi 276000,China
  • Received:2024-06-11 Revised:2024-08-05 Accepted:2024-08-23
  • Contact: WU Yibo;E-mail:bjmuwuyibo@outlook.com
    ZHANG Qingshuang,Pharmacist-in-charge;E-mail:zqs0417@163.com

高血压患者行为生活方式对生命质量的影响研究

  

  1. 1.519000 广东省珠海市,中山大学附属第五医院药学部;2.110122 辽宁省沈阳市,中国医科大学医学人文学院;3.120488 北京市,北京中医药大学中医学院;4.101300 北京市,首都医科大学燕京医学院预防医学系;5.100021 北京市朝阳区疾病预防控制中心;6.571199 海南省海口市,海南医学院公共卫生学院;7.100191 北京市,北京大学公共卫生学院;8.276000 山东省临沂市人民医院药学部
  • 通讯作者: 吴一波;E-mail:bjmuwuyibo@outlook.com
    张清霜,主管药师;E-mail:zqs0417@163.com

Abstract: Background Hypertension is one of the most prevalent chronic diseases in China,with its incidence showing a trend toward younger age groups. Unhealthy behavioral lifestyles are a significant risk factor for the development of hypertension. Therefore,it is crucial to investigate the impact of lifestyle behaviors on the quality of life in individuals with hypertension. Objective To investigate the impact of behavioral lifestyle on the quality of life in hypertensive patients and provide a scientific basis for developing effective behavioral intervention strategies. Methods The data for this study were derived from the 2022 Psychological and Behavioral Investigation of Chinese Residents(PBICR-2022),with hypertensive individuals as the study population(n=1 525). General characteristics and behavioral lifestyle information of the participants were collected. Physical activity levels were assessed using the International Physical Activity Questionnaire Short Form(IPAQ-7),and quality of life was evaluated using the European Five-Dimensional Five-Level Quality of Life Scale(EQ-5D-5L). The impact of behavioral lifestyle on quality of life was analyzed using multiple linear regression and restricted cubic spline models. Results The median EQ-5D-5L utility value was 0.951(0.893,1.000),and the median EQ-VAS score was 75.0(60.0,85.0)in hypertensive patients. The results of multiple linear regression analyses indicated that daily breakfast consumption,sleep quality,and daily sitting duration were significant factors influencing the EQ-5D-5L utility values and EQ-VAS scores(P<0.05). Current consumption of sugary beverages and average daily water intake were identified as factors influencing the EQ-VAS scores (P<0.05),while weekly physical activity level was found to be a significant factor for EQ-5D-5L utility values(P<0.05). The restricted cubic spline analysis revealed a linear dose-response relationship between daily sitting duration and both EQ-5D-5L utility values and EQ-VAS scores(Poverall trend<0.05,Pnon-linear>0.05),with both utility values and EQ-VAS scores declining as daily sitting duration increased. Additionally,a near "n" -shaped nonlinear dose-response relationship was observed between weekly physical activity level and EQ-5D-5L utility values(Poverall trend<0.05,Pnon-linea<0.05). As weekly physical activity level increased,the EQ-5D-5L utility values initially increased and then slightly decreased,with the peak occurring at a weekly physical activity level of 3,750 MET-min/week. Conclusion Adopting the habit of eating breakfast,increasing daily water intake,developing good sleep habits,and reducing the consumption of sugary beverages can improve the quality of life in hypertensive patients. In contrast,daily sitting duration exceeding four hours,as well as insufficient or excessive physical activity,may negatively impact the quality of life of hypertensive patients.

Key words: Hypertension, Quality of life, Life style, EQ-5D-5L scale, Restricted cubic spline

摘要: 背景 高血压是我国患病率较高的慢性病之一,且发病呈现“低龄化”趋势,不良行为生活方式是高血压患病的危险因素,亟须探讨行为生活方式对高血压人群生命质量的影响。目的 了解高血压患者行为生活方式对生命质量的影响,为制定有效的行为生活方式干预策略提供科学依据。方法 本研究数据来自2022年中国居民心理与行为调查研究(PBICR-2022),以高血压患病人群为研究对象(n=1 525)。收集研究对象的一般特征和行为生活方式信息,通过国际体力活动问卷短卷(IPAQ-7)评估身体活动水平,通过欧洲五维五水平生命质量量表(EQ-5D-5L)评估生命质量,采用多重线性回归和限制性立方样条法探究行为生活方式对生命质量的影响。结果 高血压患者的中位EQ-5D-5L效用值为0.951(0.893,1.000),中位EQ-VAS得分为75.0(60.0,85.0)分。多重线性回归分析结果显示,是否每日吃早餐、睡眠质量、每日坐时长是EQ-5D-5L效用值和EQ-VAS得分的影响因素(P <0.05);目前是否喝含糖饮料、日均饮水量是EQ-VAS得分的影响因素(P <0.05);每周体力活动水平是EQ-5D-5L效用值的影响因素(P <0.05)。限制性立方样条结果显示,每日坐时长与EQ-5D-5L效用值、EQ-VAS得分存在线性剂量-反应关系(P总趋势 <0.05,P非线性 >0.05),EQ-5D-5L效用值、EQ-VAS得分随每日坐时长的增加而下降;每周体力活动水平与EQ-5D-5L效用值存在近似“n”型的非线性剂量-反应关系(P总趋势 <0.05,P非线性 <0.05),随着每周体力活动水平的提高,EQ-5D-5L效用值先增加后略有下降,最高值出现在每周体力活动水平3 750 MET-min/周时。结论 养成吃早餐习惯、增加每日饮水量、养成良好的睡眠习惯、减少含糖饮料摄入有助于高血压患者生命质量的提高,每日静坐时长超过4 h、体力活动不足或过量均会降低高血压患者的生命质量。

关键词: 高血压, 生活质量, 生活方式, 欧洲五维五水平生命质量量表, 限制性立方样条

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