Chinese General Practice ›› 2023, Vol. 26 ›› Issue (25): 3170-3177.DOI: 10.12114/j.issn.1007-9572.2022.0687
• Original Research·Appropriate Health Technology • Previous Articles Next Articles
Received:
2022-09-23
Revised:
2023-04-19
Published:
2023-09-05
Online:
2023-05-25
Contact:
ZHANG Dufei
通讯作者:
张笃飞
作者简介:
基金资助:
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URL: https://www.chinagp.net/EN/10.12114/j.issn.1007-9572.2022.0687
疾病类型 | 例数 |
---|---|
房间隔缺损 | 201(38.14) |
室间隔缺损 | 135(25.62) |
动脉导管未闭 | 104(19.73) |
肺动脉瓣狭窄 | 17(3.22) |
部分型肺静脉异位引流 | 10(1.89) |
法洛氏四联症 | 9(1.71) |
部分型房室间隔缺损 | 7(1.33) |
主动脉缩窄 | 5(0.95) |
主动脉弓离断 | 5(0.95) |
完全型肺静脉异位引流 | 4(0.76) |
完全型大动脉转位 | 4(0.76) |
肺动脉瓣闭锁 | 4(0.76) |
单心室 | 3(0.57) |
右心室双出口 | 2(0.38) |
完全型房室间隔缺损 | 2(0.38) |
先天性右位主动脉弓 | 2(0.38) |
先天性左房室瓣裂 | 1(0.19) |
左室流出道狭窄 | 1(0.19) |
主动脉肺动脉间隔缺损 | 1(0.19) |
先天性双主动脉弓 | 1(0.19) |
肺动脉吊带 | 1(0.19) |
主动脉弓狭窄 | 1(0.19) |
左心室双出口 | 1(0.19) |
先天性主动脉瓣狭窄 | 1(0.19) |
先天性主动脉瓣二叶瓣畸形 | 1(0.19) |
先天性右房室瓣狭窄 | 1(0.19) |
先天性肺动脉缺如 | 1(0.19) |
先天性头臂动脉畸形 | 1(0.19) |
先天性肺动脉异常 | 1(0.19) |
Table 1 Distribution of subtypes of CHD in neonates
疾病类型 | 例数 |
---|---|
房间隔缺损 | 201(38.14) |
室间隔缺损 | 135(25.62) |
动脉导管未闭 | 104(19.73) |
肺动脉瓣狭窄 | 17(3.22) |
部分型肺静脉异位引流 | 10(1.89) |
法洛氏四联症 | 9(1.71) |
部分型房室间隔缺损 | 7(1.33) |
主动脉缩窄 | 5(0.95) |
主动脉弓离断 | 5(0.95) |
完全型肺静脉异位引流 | 4(0.76) |
完全型大动脉转位 | 4(0.76) |
肺动脉瓣闭锁 | 4(0.76) |
单心室 | 3(0.57) |
右心室双出口 | 2(0.38) |
完全型房室间隔缺损 | 2(0.38) |
先天性右位主动脉弓 | 2(0.38) |
先天性左房室瓣裂 | 1(0.19) |
左室流出道狭窄 | 1(0.19) |
主动脉肺动脉间隔缺损 | 1(0.19) |
先天性双主动脉弓 | 1(0.19) |
肺动脉吊带 | 1(0.19) |
主动脉弓狭窄 | 1(0.19) |
左心室双出口 | 1(0.19) |
先天性主动脉瓣狭窄 | 1(0.19) |
先天性主动脉瓣二叶瓣畸形 | 1(0.19) |
先天性右房室瓣狭窄 | 1(0.19) |
先天性肺动脉缺如 | 1(0.19) |
先天性头臂动脉畸形 | 1(0.19) |
先天性肺动脉异常 | 1(0.19) |
方法 | 人数 | 真阳性数〔人(%)〕 | 假阳性数〔人(%)〕 | 真阴性数〔人(%)〕 | 假阴性数〔人(%)〕 | 灵敏度(95%CI) (%) | 特异度(95%CI) (%) | 阳性预测值(95%CI)(%) | 阴性预测值(95%CI)(%) | 约登指数 |
---|---|---|---|---|---|---|---|---|---|---|
心脏杂音听诊法 | 204 442 | 358(0.18) | 3 937(1.93) | 199 978(97.82) | 169(0.08) | 67.93(63.73,71.87) | 98.07(98.01,98.13) | 8.34(7.53,9.21) | 99.92(99.90,99.93) | 0.66 |
POX测定法 | 204 442 | 195(0.10) | 1 466(0.72) | 202 449(99.03) | 332(0.16) | 37.00(32.89,41.30) | 99.28(99.24,99.32) | 11.74(10.25,13.41) | 99.84(99.82,99.85) | 0.36 |
双指标联合法 | 204 442 | 492(0.24) | 5 355(2.62) | 198 560(97.12) | 35(0.02) | 93.35(90.79,95.26) | 97.37(97.30,97.44) | 8.41(7.72,9.16) | 99.98(99.97,99.99) | 0.91 |
Table 2 Values of different indicators for neonatal CHD screening
方法 | 人数 | 真阳性数〔人(%)〕 | 假阳性数〔人(%)〕 | 真阴性数〔人(%)〕 | 假阴性数〔人(%)〕 | 灵敏度(95%CI) (%) | 特异度(95%CI) (%) | 阳性预测值(95%CI)(%) | 阴性预测值(95%CI)(%) | 约登指数 |
---|---|---|---|---|---|---|---|---|---|---|
心脏杂音听诊法 | 204 442 | 358(0.18) | 3 937(1.93) | 199 978(97.82) | 169(0.08) | 67.93(63.73,71.87) | 98.07(98.01,98.13) | 8.34(7.53,9.21) | 99.92(99.90,99.93) | 0.66 |
POX测定法 | 204 442 | 195(0.10) | 1 466(0.72) | 202 449(99.03) | 332(0.16) | 37.00(32.89,41.30) | 99.28(99.24,99.32) | 11.74(10.25,13.41) | 99.84(99.82,99.85) | 0.36 |
双指标联合法 | 204 442 | 492(0.24) | 5 355(2.62) | 198 560(97.12) | 35(0.02) | 93.35(90.79,95.26) | 97.37(97.30,97.44) | 8.41(7.72,9.16) | 99.98(99.97,99.99) | 0.91 |
组别 | 人数 | 重症CHD患儿〔例(%)〕 |
---|---|---|
心脏杂音听诊结果为阳性 | 4 295 | 29(0.68)a |
POX测定结果为阳性 | 1 661 | 21(1.26)a |
两项指标(心脏杂音听诊结果、POX测定结果)均为阳性 | 109 | 44(40.37) |
χ2值 | 1 098.787 | |
P值 | <0.001 |
Table 3 Relationships between severe CHD and screening indicators
组别 | 人数 | 重症CHD患儿〔例(%)〕 |
---|---|---|
心脏杂音听诊结果为阳性 | 4 295 | 29(0.68)a |
POX测定结果为阳性 | 1 661 | 21(1.26)a |
两项指标(心脏杂音听诊结果、POX测定结果)均为阳性 | 109 | 44(40.37) |
χ2值 | 1 098.787 | |
P值 | <0.001 |
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