Precautions for the Treatment of Ulcerative Colitis with Traditional Chinese Medicine Retention Enema

doi:10.12114/j.issn.1007-9572.2019.00.088

Abstract

Abstract: A large number of clinical practice has proved that Chinese medicine retention enema has a significant effect on ulcerative colitis.Current clinical research on the treatment of ulcerative colitis with Chinese medicine retention enema is mainly focused on the components，and compatibility of Chinese medicine，action of mechanism of the therapy，and combined medication.However，to achieve good clinical results，besides good rationality of prescription compatibility，appropriate means by which the drugs can yield increased in vivo efficacy are also needed.On the basis of reviewing related studies，the article discusses the types of Chinese medicine retention enema and related precautions.

Key words: Colitis, ulcerative；Enema；Traditional Chinese pharmacy

摘要： 大量临床实践表明，中药保留灌肠治疗溃疡性结肠炎效果显著。目前关于中药保留灌肠治疗溃疡性结肠炎的临床研究主要集中在中药配伍及机制、联合用药等方面。要想获得良好的临床疗效，除了良好的配伍处方外，还需要合适的治疗措施，才能让药物更好地在患者体内发挥作用。本文结合相关文献，重点讨论中药保留灌肠治疗溃疡性结肠炎的方式及相关注意事项。

关键词: 结肠炎, 溃疡性；灌肠；中药学

LI Wei,HU Fenglin,LI Jiyan 3. Precautions for the Treatment of Ulcerative Colitis with Traditional Chinese Medicine Retention Enema　[J]. Chinese General Practice, 2019, 22(30): 3714-3716. DOI: 10.12114/j.issn.1007-9572.2019.00.088.
李薇,胡凤林,李吉彦. 中药保留灌肠治疗溃疡性结肠炎的相关注意事项[J]. 中国全科医学, 2019, 22(30): 3714-3716. DOI: 10.12114/j.issn.1007-9572.2019.00.088.

References

［1］YU W，LI Z，LONG F，et al．A systems pharmacology approach to determine active compounds and action mechanisms of Xipayi Kuijie'an enema for treatment of ulcerative colitis［J］．Sci Rep，2017，7（1）：1189．DOI：10.1038/s41598-017-01335-w.
［2］李毅，陈更生，刘艳，等．聚类分析和Logistic 回归分析对活动期溃疡性结肠炎症状规律的研究［J］．中医学报，2018，33（5）：770-774．DOI：10.16368/j.issn.1674-8999.2018.05.183.
［3］李军祥，陈誩.溃疡性结肠炎中西医结合诊疗共识意见（2017年）［J］．中国中西医结合消化杂志，2018，26（2）：105-111，120．DOI：10.3969/j.issn.1671-038X.2018.02.01.
［4］霍红，张怡，吴贵恺，等．紫艾汤保留灌肠联合美沙拉嗪肠溶片口服治疗远端结肠型溃疡性结肠炎的临床效果［J］．中华中医药学刊，2018，36（3）：748-750．DOI：10.13193/j.issn.1673-7717.2018.03.061.
［5］董雪莲，常玉洁，吴艳红，等．不同时辰中药保留灌肠对治疗溃疡性结肠炎的随机对照研究［J］．成都中医药大学学报，2018，41（1）：64-67．DOI：10.13593/j.cnki.51-1501/r.2018.01.064.
［6］俎桂英，常玉洁，董雪莲，等．子午流注中药保留灌肠配合热敏灸法治疗溃疡性结肠炎临床观察［J］．四川中医，2017，35（3）：77-79.
［7］胡鹏.溃疡性结肠炎中药灌肠治疗及护理探讨［J］．实用临床护理学电子杂志，2017，2（39）：10.
［8］李双妮.清洁灌肠后保留灌肠治疗溃疡性结肠炎临床护理［C］．//国际数字医学会．2017国际数字医学会数字中医药分会论文集，2017：2.
［9］原林.灌肠在消化内科疾病治疗中的应用［J］．国际消化病杂志，2015，35（4）：286-288.
［10］焦威.胃管代替肛管灌肠在急性发作溃疡性结肠炎中的应用效果评价［J］．实用临床医药杂志，2016，20（24）：90-91.
［11］裴月辉.结肠透析仪中药保留灌肠治疗慢性结肠炎的护理体会［J］．中国医药指南，2016，14（17）：270.
［12］刘洪利，王晓.内镜下导管注药治疗重度溃疡性结肠炎的临床分析［J］．求医问药（下半月），2012，10（6）：304-305.
［13］杨红伟，杨新惠，叶丽娜.结肠镜高位药物灌肠治疗溃疡性结肠炎80例疗效观察［J］．兵团医学，2015，46（4）：11-12.
［14］原文静，毛堂友，李军祥.中医药通过调整肠道微生态治疗溃疡性结肠炎的研究现状［J］．世界科学技术-中医药现代化，2018，20（4）：579-584.
［15］于姣，何瑾瑜，张蕾.中药灌肠对溃疡性结肠炎患者的临床疗效及其对肠道菌群的影响［J］．中国微生态学杂志，2017，29（11）：1323-1325，1329．DOI：10.13381/j.cnki.cjm.201711022.
［16］鲁睿.溃疡性结肠炎患者肠愈灌肠方保留灌肠治疗的疗效观察及护理［J］．实用临床护理学电子杂志，2017，2（46）：172，181.
［17］亢英，张娜.慢性溃疡性结肠炎的蒙药灌肠治疗和护理［J］．中国民族医药杂志，2017，23（1）：75-76.
［18］林春敏，李欣欣，蒋英姿.影响溃疡性结肠炎患者灌肠效果的相关参数进展［J］．中华护理教育，2013，10（3）：134-135．DOI：10.3761/j.issn.1672-9234.2013.03.016.
［19］孙晓艳，王锐，吉强，等．白头翁汤加味联合保留灌肠治疗溃疡性结肠炎的临床疗效观察［J］．世界中西医结合杂志，2018，13（3）：366-369．DOI：10.13935/j.cnki.sjzx.180317.
［20］李芬，刘丽颖，张继红.溃疡性结肠炎保留灌肠体位指导临床研究［J］．实用临床医药杂志，2014，18（2）：91-92．DOI：10.7619/jcmp.201402035.
［21］尚艳，何晓伟.不同插管方法和深度对灌肠效果的影响［J］．西北国防医学杂志，2012，33（4）：487-488.
［22］中华医学会.临床技术操作规范?护理分册［M］．北京：人民军医出版社，2005：9.
［23］卢英，金哲，王丹.不同插管深度中药保留灌肠对盆腔炎性疾病止痛效果的影响［J］．北京中医药大学学报（中医临床版），2012，19（2）：48-50．DOI：10.3969/j.issn.1672-2205.2012.02.016.　［24］庄小燕.不同灌肠药液量对溃疡性直肠炎患者保留灌肠效果的影响［J］．医学理论与实践，2015，28（23）：3212-3214.
［25］张翠霞，苗子江.结肠途径治疗溃疡性结肠炎68例观察［J］．中国医学创新，2010，7（34）：179-180.
［26］顾秀梅.改变灌肠液温度对治疗溃疡性结肠炎疗效的影响［J］．医学理论与实践，2016，29（8）：1047-1048.

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