In Vitro Evaluation of Antithrombotic and Anticoagulant Effects of Shuxuetong Injection
1.Mudanjiang Youbo Pharmaceutical Corporation,Ltd,Mudanjiang 157013,China
2.Beijing Youbo Pharmaceutical Corporation,Ltd,Beijing 101300,China
3.School of Pharmaceutical Science Technology of Tianjin University/Tianjin Key Laboratory of Modern Drug Delivery and High Efficiency,Tianjin 300072,China
4.The First Hospital Affiliated to Soochow University/Jiangsu Institute of Hematology/Key Laboratory of Thrombosis and Hemostasis,Suzhou 215006,China
*Corresponding author:JIANG Miao,Professor,Chief physician;E-mail:jiangmiao@suda.edu.cn
[1]王月环.疏血通注射液治疗冠心病不稳定型心绞痛50例临床观察[J].中西医结合心脑血管病杂志,2013,11(6):758-759.DOI:10.3969/j.issn.1672-1349.2013.06.061.
WANG Y H.Clinical observation on 50 cases of unstable angina pectoris of coronary heart disease treated by Shuxuetong Injection[J].Chinese Journal of Integrative Medicine on Cardio/Cerebrovascular Disease,2013,11(6):758-759.DOI:10.3969/j.issn.1672-1349.2013.06.061.
[2]臧召霞,朴钟源,刘志强,等.疏血通注射液对急性脑梗死患者血脂、血浆PAI-1、纤维蛋白原的影响[J].中国中医急诊,2014,23(1):131-132.DOI:10.3969/j.issn.1004-745X.2014.01.066.
ZANG Z X,PU Z Y,LIU Z Q,et al.Effect of Shuxuetong Injection on blood lipids,plasma PAI-1,and fibrinogen in patients with acute cerebral infarction[J].Journal of Emergency in Traditional Chinese Medicine,2014,23(1):131-132.DOI:10.3969/j.issn.1004-745X.2014.01.066.
[3]邓书禄.联合应用疏血通注射液治疗对急性心肌梗死患者凝血、生化指标和心电图的影响[J].微循环学杂志,2015,25(1):51-54.DOI:10.3969/j.issn.1005-1740.2015.01.013.
DENG S L.Effect of combination therapy of Shuxuetong Injection and therapies on blood coagulation,bio-chemical indexes and electrocardiogram in acute myocardial infarction patient[J].Journal of Microcirculation,2015,25(1):51-54.DOI:10.3969/j.issn.1005-1740.2015.01.013.
[4]LU W F,MO W,LIU Z,et al.The antithromboticeffect of a novel hirudin derivative after reconstruction of carotid artery in rabbits[J].Thromb Res,2010,126(4):e339-343.DOI:10.1016/j.thromres.2010.03.022.
[5]JI H,WANG L,BI H,et al.Mechanisms of lumbrokinase in protection of cerebral ischemia[J].Eur J Pharmacol,2008,590(1):281-289.
[6]黄越冬,徐书雯,肖豪,等.疏血通注射液对高卒中风险短暂性脑缺血发作患者纤溶系统及预后的影响[J].中西医结合心脑血管病杂志,2012,10(3):311-313.DOI:10.3969/j.issn.1672-1349.2012.03.031.
HUANG Y D,XU S W,XIAO H,et al.Effect of Shuxuetong Injection on coagulation-fibrinolytic systems and prognosis in transient ischemic attack at high-risk of stroke[J].Chinese Journal of Integrative Medicine on Cardio/Cerebrovascular Disease,2012,10(3):311-331.DOI:10.3969/j.issn.1672-1349.2012.03.031.
[7]GREMMEL T,KOPPENSTEINER R,KAIDER A,et al.Impact of variables of the P-selectin - P-selectin glycoprotein ligand-1 axis on leukocyte-platelet interactions in cardiovascular disease[J].Thromb Haemost,2015,113(4):806-812.DOI:10.1160/TH14-08-0690.
[8]张璇,肖兵,胡长林.疏血通注射液抗栓、溶栓作用机制的研究[J].中国中药杂志,2005,30(24):1950-1952.DOI:10.3321/j.issn.1001-5302.2005.24.020.
ZHANG X,XIAO B,HU C L.Study in the mechanism of Shuxuetong Injection on antithrombosis and thrombolysis[J].Chinese Journal of Traditional Chinese Medicine,2005,30(24):1950-1952.DOI:10.3321/j.issn.1001-5302.2005.24.020.