Loading...

Table of Content

    05 September 2025, Volume 28 Issue 25
    Editorial
    Primary Care Reimagined: Economic, Health and Service Delivery Dimensions
    YANG Hui
    2025, 28(25):  0-C6.  DOI: 10.12114/j.issn.1007-9572.2025.A0030
    Asbtract ( )   HTML ( )   PDF (1009KB) ( )  
    References | Related Articles | Metrics
    Standard·Specifications·Guidelines
    Specification for the Integration of Healthcare and Prevention Services in Hypertension at the Primary Level
    TANG Shangfeng, HUANG Yangzhen, PAN Yangyang, ZHENG Yanxi, XIONG Zhongbao, ZHANG Kangkang, SONG Jia, WEI Yilin, WANG Chunying, DONG Heng, CHEN Manwei, QING Hua
    2025, 28(25):  3089-3095.  DOI: 10.12114/j.issn.1007-9572.2024.0414
    Asbtract ( )   HTML ( )   PDF (1382KB) ( )  
    Figures and Tables | References | Related Articles | Metrics

    Hypertension is one of the most prevalent chronic diseases in China. As of 2021, there are over 270 million people suffering from hypertension in our country, which is the most significant risk factor for the death of urban and rural residents due to cardiovascular and cerebrovascular diseases. China has now entered the stage of comprehensively building a Healthy China, and exploring the construction of a chronic disease management path with the integration of healthcare and prevention as the core has become an important trend. This specification is based on the existing content and process of hypertension integration of healthcare and prevention services, and formulates standardized service diagnostic and treatment norms for the integration of hypertension healthcare and prevention. The content of the specification mainly includes basic requirements for service provision, service content, service process, etc., aiming to optimize the primary diagnosis and treatment and health management process of hypertension, control the incidence and mortality of hypertension, and reduce and delay the occurrence of complications, thereby effectively building a primary prevention and treatment line for chronic diseases.

    Specification for the Integration of Healthcare and Prevention Services in Diabetes at the Primary Level
    TANG Shangfeng, HUANG Yangzhen, ZHENG Yanxi, PAN Yangyang, XIONG Zhongbao, QING Hua, SONG Jia, WEI Yilin, DONG Heng, WANG Chunying, CHEN Manwei, ZHANG Kangkang
    2025, 28(25):  3096-3103.  DOI: 10.12114/j.issn.1007-9572.2024.0415
    Asbtract ( )   HTML ( )   PDF (1444KB) ( )  
    Figures and Tables | References | Related Articles | Metrics

    In recent years, the prevalence of diabetes among adults in China has continued to rise, reaching as high as 11.9%, with with type 2 diabetes mellitus (T2DM) being the main type, accounting for more than 90% of the diabetic population, and the onset of the disease is becoming increasingly younger. China has now entered the stage of comprehensively building a Healthy China, and exploring the construction of a chronic disease management path with the integration of healthcare and prevention as the core has become an important trend. This specification, based on the existing content and process of the integration of healthcare and prevention services for T2DM, formulates standardized diagnostic and treatment specifications for the integration of healthcare and prevention services for T2DM. The content of the specification mainly includes basic requirements for service provision, content of services, and service processes, aiming to optimize the primary diagnosis and treatment and health management process of T2DM, control the incidence and mortality rate of T2DM through early detection and comprehensive management, and reduce and delay the occurrence of complications, thereby effectively building a primary prevention and treatment line for chronic diseases.

    Article
    Wearable Acoustic-electrocardiographic Remote Monitoring Device for Heart Failure
    LIU Wenjie, SUN Huang, LUO Wei, CHEN Xuan, PENG Yunzhu, LI Ruijie, MA Mier
    2025, 28(25):  3104-3109.  DOI: 10.12114/j.issn.1007-9572.2023.0820
    Asbtract ( )   HTML ( )   PDF (1485KB) ( )  
    Figures and Tables | References | Related Articles | Metrics
    Background

    Early assessment and prompt treatment for heart failure patients can prevent the occurrence of cardiac adverse events. Effective diagnostic tools are particularly crucial for these patients. Acoustic Cardiography (ACG) , as an efficient and non-invasive bedside screening tool, can be used to evaluate the severity of heart failure.

    Objective

    To investigate the feasibility of using a wearable acoustic-electrocardiographic remote monitoring device for dynamic cardiac function assessment during heart failure treatment.

    Methods

    This prospective single-arm self-controlled study randomly enrolled 60 patients with acute heart failure admitted to the Department of Cardiology, the first Affiliated Hospital of Kunming Medical University, from October 2020 to December 2020. Key parameters, including electro-mechanical activation time (EMAT) , EMAT percentage (EMAT%) , N-terminal pro-B-type natriuretic peptide (NT-proBNP) , and body weight, were measured on admission days 1, 2, 3, 5, and discharge day. Echocardiographic parameters were assessed on admission and discharge days. Trends in parameter changes and consistency among indicators were analyzed.

    Results

    Among the 60 patients (35 males, 25 females) , the average hospitalization duration was (7.9±3.2) days. One-way repeated measures ANOVA revealed statistically significant differences in EMAT, EMAT%, NT-proBNP, and body weight across time points (FEMAT=6.978, P<0.01; FEMAT%=3.108, P<0.05; FNT-proBNP=8.678, P<0.01; Fweight=27.246, P<0.01) . Pairwise comparisons demonstrated sequential decreases in these parameters from admission to discharge (P<0.01) . No significant differences were observed in echocardiographic parameters before and after treatment (P>0.05) . Time-adjusted repeated measures ANOVA confirmed consistent trends between EMAT and NT-proBNP changes during hospitalization (Day 1: β=67.724, P<0.01; Day 2: β=56.876, P<0.01; Day 3: β=38.503, P<0.01; Day 5: β=23.969, P<0.01; discharge: β=16.851, P<0.05) .

    Conclusion

    Compared to bedside echocardiography (e.g., LVEF) and NT-proBNP testing, the wearable acoustic-electrocardiographic remote monitoring device offers non-invasive, convenient, and cost-effective advantages. The device captures dynamic changes in acoustic and electrocardiographic parameters that correlate with clinical improvements in heart failure patients, suggesting its potential for remote cardiac function monitoring and timely detection of disease progression.

    Constructing a Comprehensive Community Clinical Pathway for Herpes Zoster under Graded Treatment Framework
    JI Bing, JIANG Dudu, CHEN Chen, ZHENG Yanling, SHI Jianwei, FANG Lizheng, DU Xueping
    2025, 28(25):  3110-3118.  DOI: 10.12114/j.issn.1007-9572.2024.0461
    Asbtract ( )   HTML ( )   PDF (1740KB) ( )  
    Figures and Tables | References | Related Articles | Metrics
    Background

    Early diagnosis and treatment of herpes zoster (HZ) are crucial in reducing post-herpetic neuralgia complications. However, research on prevention and treatment at the primary healthcare level remains insufficient.

    Objective

    Based on the hierarchical diagnosis and treatment system between community health service centers and general hospitals, this study aims to establish a comprehensive community-based clinical pathway for HZ, providing guidelines for standardized management in community settings.

    Methods

    Through a systematic review spanning from 2003 to 2023, international and domestic literature on HZ prevention, diagnosis, pain assessment tools, and treatment measures were collated. Utilizing focus group discussions, 12 experts engaged in HZ-related work or research from Shanghai, Beijing, including representatives from disease control centers, health commissions, comprehensive hospitals, and community health centers, refined and constructed the clinical pathway and operational protocols for community HZ diagnosis and treatment.

    Results

    Within the hierarchical medical system, the community-based pathway for HZ diagnosis and treatment encompasses stages of prevention, diagnosis and differential diagnosis, treatment, and follow-up. The established pathway assigns initial HZ diagnosis, graded treatment, and follow-up responsibilities to community health service centers while general hospitals handle specialized differential diagnoses and non-basic services. This pathway is anchored by community general practitioners as its central axis.

    Conclusion

    The community-based pathway for diagnosing and treating HZ developed in this study, within the framework of a hierarchical medical system, can effectively enhance the standardization of HZ diagnosis and treatment in primary healthcare institutions. Moreover, it establishes a solid clinical and theoretical foundation for promoting a two-way referral model of HZ under nationwide hierarchical diagnosis and treatment.

    Matching Analysis of the Content of Chronic Disease Management for the Elderly in Medical Union: Based on the Perspective of "Guidance-Practice-Need"
    YAN Fanghong, PENG Guotian, ZHANG Guoli, SUN Ruiyi, MA Yuxia, HAN Lin
    2025, 28(25):  3119-3126.  DOI: 10.12114/j.issn.1007-9572.2023.0455
    Asbtract ( )   HTML ( )   PDF (1911KB) ( )  
    Figures and Tables | References | Related Articles | Metrics
    Background

    Chronic disease management is a major challenge in an aging society, and medical union is a powerful way to solve the problem of chronic diseases in the elderly in China. At present, existing studies have summarized the management practice of medical union and the needs of elderly patients with chronic diseases, and relevant institutions and experts organized by government departments have also formulated corresponding guidelines and technical scheme. However, from the perspective of disease management, the matching status of specific management content from the three perspectives of guideline recommendation evidence, practice status and patient needs should be further studied.

    Objective

    To clarify the evidence resources of elderly chronic disease management in the medical alliance and analyze the matching status between service resources and service needs from the perspectives of "Guidance-Practice-Need".

    Methods

    Framed by the Arksey and O&apos;Malley scoping review framework, an analysis was conducted on the management of two diseases (hypertension and diabetes) from Jonuary 2023 to April 2024. The relevant guidelines or technical schemes from inception to December 2020 and other types of literature from August 2011 to December 2020 on the management of elderly chronic diseases (hypertension, diabetes) in the medical alliance was systematically retrieved. After removing duplicate and screening, the data were extracted, and the management content and responsible organizations were summarized by descriptive method and content analysis method, and the matching status between service resources and service demands was compared with the presentation of tables, graphs and summary paragraphs.

    Results

    A total of 35 articles from 14 provinces and regions were included, covering 39 items of management content in 12 categories. Nine guidelines and technical plans literatures were included to describe 19 items of management content in 6 categories, 21 literatures on practice status introduced 24 items of management content in 9 categories, and another 6 literatures analyzed 32 items of patient needs in 12 categories. There were great differences in management content under the 3 perspectives, and the main responsible organizations of the two perspectives of guidance and practice were different.

    Conclusion

    The matching results of supply and demand of management content suggest that future research can explore the efficient utilization path of independent service resources of chronic disease management in demand-oriented medical alliances, while the matching results of responsible institutions of specific management content suggest that future research should explore how to optimize the resource allocation of primary medical institutions on the basis of strengthening the two-way referral channel, and determine the responsibility of patients and families to participate in chronic disease management.

    Survey of General Practitioners&apos; Cognition and Needs for AI Assisted Diagnosis and Treatment Systems
    PAN Qi, REN Jingjing, MA Fanghui, HU Mengjie
    2025, 28(25):  3127-3136.  DOI: 10.12114/j.issn.1007-9572.2024.0599
    Asbtract ( )   HTML ( )   PDF (1944KB) ( )  
    Figures and Tables | References | Related Articles | Metrics
    Background

    Artificial Intelligence (AI) is a crucial component of China&apos;s new-generation information technology development strategy. With its extensive applications in the healthcare field, the integration of AI into general practice for auxiliary diagnosis and chronic disease management plays a significant role in enhancing primary healthcare services and improving the professional skills and clinical decision-making capabilities of general practitioners.

    Objective

    Through a preliminary investigation into general practitioners&apos; cognition of AI technology in the medical field and their needs for constructing auxiliary diagnosis and treatment systems across various provinces and cities, this study aims to provide references for establishing more clinically applicable AI-assisted diagnosis and treatment systems.

    Methods

    From March to April 2024, we selected general practitioners (GPs) from across China&apos;s provinces and municipalities as study participants through national GP WeChat groups. Using a self-designed questionnaire, we collected data on: GPs&apos; basic demographic information; their attitudes toward and understanding of AI-assisted diagnosis and treatment systems; and their needs regarding AI applications in daily clinical practice (including clinical consultations, auxiliary diagnosis and treatment, referral and follow-up, and application formats) . Data collection was conducted via the"Questionnaire Star" platform, and descriptive analysis methods were employed to present and characterize the results.

    Results

    This study enrolled 382 general practitioners (GPs) from 27 provinces across China, comprising 52.36% (200/382) from general hospitals and 47.64% (182/382) from primary healthcare institutions. The survey revealed that 57.69% (220/382) of respondents believed physicians and AI should work synergistically, while 77.75% (297/382) of practitioners expressed willingness to adopt or continue using AI-assisted diagnostic technologies in clinical practice; The survey identified key advantages of AI adoption, including improved diagnostic efficiency [89.01% (340/382) ] , reduced clinical workload [84.29% (322/382) ] , and decreased misdiagnosis rates 80.10% (306/382) . However, significant concerns were noted regarding: over-reliance on AI diagnosis [75.13% (287/382) , ethical implications [64.14% (245/382) ] , algorithmic diagnostic bias [63.09% (241/382) ] , data security vulnerabilities [57.33% (219/382) ] , and liability ambiguity in medical incidents [53.66% (205/382) ] ; In the clinical consultation needs assessment, general practitioners most frequently requested AI-enabled alerts for"life-threatening conditions" [61.25% (234/382) ] and prompts for"urgently actionable clinical signs" [62.04% (237/382) ] . Significant demand was also observed for"associated symptom inquiry prompts" [58.90% (225/382) ] and"systematic clinical reasoning guidance" [62.57% (239/382) ] ; In the auxiliary diagnosis and treatment domain, rapid and precise imaging evaluation [67.80% (259/382) ] and prescription review [67.01% (256/382) ] emerged as the most anticipated AI functions. Significant attention was also given to personalized medication recommendations [63.88% (244/382) ] and insurance coverage alerts [66.49% (254/382) ] ; Regarding referral and follow-up management, general practitioners showed the strongest demand for three key AI functions: automated reminders for follow-up visit scheduling [72.25% (276/382) ] , remote monitoring capabilities through smart devices [71.46% (273/382) ] and personalized delivery of patient education content [70.42% (269/382) ] ; In terms of system application formats, general practitioners showed the strongest preference for"reviewing patients&apos; historical medical records" [73.04% (279/382) ] and"voice-to-text transcription" [71.73% (274/382) ] ; In terms of priorities for incorporating undifferentiated diseases into AI-assisted diagnostic and treatment systems, 37.43% (143/382) of general practitioners recommended prioritizing the inclusion of fever in AI-assisted diagnosis and treatment systems.

    Conclusion

    General practitioners demonstrated overall high willingness to adopt AI technology for clinical diagnosis and treatment. The AI-assisted clinical decision support system showed significant demand across multiple clinical workflows, including medical history collection, physical examination, diagnostic testing, treatment planning, referral criteria determination, follow-up management, and system application formats. Moving forward, the development of AI-assisted diagnosis and treatment systems tailored for Chinese general practitioners—through overcoming technological limitations, establishing clear legal frameworks and guidelines for AI, and enhancing GPs&apos; AI literacy—will significantly improve primary care physicians&apos; first-contact diagnostic capabilities and facilitate the implementation of tiered healthcare delivery systems.

    Analysis of the Prevalence and Self-management of Hypertension and Its Influencing Factors in Rural
    YU Zizi, LIU Duli, LI Ximin, RUAN Chunyi, YIN Xiangyang, CAI Le
    2025, 28(25):  3137-3143.  DOI: 10.12114/j.issn.1007-9572.2024.0249
    Asbtract ( )   HTML ( )   PDF (1883KB) ( )  
    Figures and Tables | References | Related Articles | Metrics
    Background

    The control of hypertension is still unsatisfactory, as the number of patients continues to increase in China, and self-management plays a positive role in the prevention of relevant complications and reducing the economic burden of the disease. The influencing factors of prevalence and self-management are varied, but few studies have identified path coefficients and indirect effects between factors.

    Objective

    The aim of this study was to analyse the prevalence of hypertension and self-management and their influencing factors in rural Dayao County, Yunnan Province.

    Methods

    A multistage stratified random sampling method was used to select 2 499 rural residents aged≥35 years from Dayao County. Each participant received a questionnaire survey and underwent physical examination. Principal component analysis was used to construct the index of socioeconomic position (SEP) , whereas structural equation modelling (SEM) was used to analysis the possible influencing factors of the prevalence of hypertension and self-management.

    Results

    Among the surveyed population, the prevalence of hypertension was 53.7%, and the rate of compliance to anti-hypertensive drugs, self-monitoring of blood pressure and taking measures to control hypertension was 84.5%, 82.0% and 88.3%, and was 52.4%, 82.2%, 80.8% and 87.8% for males and 55.0%, 86.8%, 83.2% and 88.8% for females, respectively. The prevalence of hypertension increased with age (χ2trend=224.142, P<0.001), whereas the rate of self-monitoring of blood pressure decreased (χ2trend=4.012, P<0.05). A greater prevalence of hypertension was observed in those with lower education levels and SEP (χ2=28.036, χ2trend=12.147, P<0.001) . Individuals with good access to medical services had a higher rate of self-monitoring of blood pressure than their counterparts did (χ2=10.137, P<0.05) . The result of SEM indicated that the following factors had a direct statistically significant effect on the prevalence of hypertension: SEP (-0.43) , body shape (including overweight or obesity and central obesity status) (0.16) , physical inactivity (0.06) , and family history of hypertension (0.15) . However indirect effects on the prevalence of hypertension were observed for sex (0.23, through SEP) and age (0.35, through SEP and physical inactivity) . Similarly, the results also indicated that SEP (0.20) , alcohol consumption (-0.17) , and conditions of hypertensive patients (including the course of disease and complications) (0.53) had a statistically significant direct effect on the prevalence of self-management, while gender (0.06) had an indirect effect on prevalence of self-management through alcohol consumption.

    Conclusion

    There is a relatively high prevalence of hypertension and an overall high level of self-management in rural Dayao County. Future health education and management regarding hypertension should be strengthened for the elderly and individuals with low SEP and unhealthy lifestyles.

    Study of Behavioral Intention and Influencing Factors of Integrated Medical and Preventive Care Provided by Grassroots Doctors for Patients with Chronic Diseases
    FAN Boyang, ZHANG Yu, SUN Wenning, ZHANG Huifang, WANG Yingjie, ZHANG Ao, ZHAO Yang, WANG Haipeng
    2025, 28(25):  3144-3150.  DOI: 10.12114/j.issn.1007-9572.2024.0362
    Asbtract ( )   HTML ( )   PDF (1749KB) ( )  
    Figures and Tables | References | Related Articles | Metrics
    Background

    Chronic diseases have become a significant public health issue in China. Due to the prolonged course and difficulty in achieving a cure, it is essential to promote full-life-cycle integrated medical and preventive care for prevention and treatment of chronic diseases. However, medical services and public health services in China are separatedand there is still a gap in the supply of integrated medical and preventive care. Grassroots doctors are key providers of such services, and their behavior directly impacts the quality of integrated medical and preventive care. Therefore, it is crucial to explore the behavioral intention of grassroots doctors in providing integrated medical and preventive care for chronic diseases.

    Objective

    This study investigates the current status and influencing factors of the behavioral intention of integrated medical and preventive care provided by grassroots doctors for patients with chronic diseases in Shandong Province. The aim of the study was to offer insights and guidance for improving the quality of integrated medical and preventive care at the grassroots level.

    Methods

    A total of 481 grassroots doctors were collected through multi-stage stratified cluster random sampling in Shandong Province. A questionnaire survey was conducted to investigate grassroots doctors&apos; behavioral intention to integrate medical and preventive care, and the influencing factors were analyzed using univariate analysis and binomial logistic regression. The questionnaire of this study was entitled "Questionnaire on the behavioral intention of integrated medical and preventive care provided by grassrootd doctors for patients with chronic diseases" and its content was modified after expert consultation. The questionnaire mainly includes four parts: questionnaire on general situation, questionnaire on the awareness of integrated medical and preventive care, questionnaire on the assessment of the environment of integrated medical and preventive care in grassroots medical institutions, and questionnaire on the behavioral intention of integrated medical and preventive care provided by grassroots doctors.

    Results

    83.16% (400/481) of grassroots doctors had a high level of behavioral intention to provide integrated medical and preventive care. Grassroots doctors who were female (OR=2.149) , had junior college diploma (OR=2.736) , had a higher level of awareness of integrated medical and preventive care (OR=3.549) , and were employed in the organizations with better environment (OR=8.264) had a stronger behavioral intention to provide integrated medical and preventive care (P<0.05) .

    Conclusion

    Currently, grassroots doctors show strong behavioral intention to provide integrated medical and preventive care for patients with chronic diseases. However, it is still necessary to establish a sound incentivization mechanism. A variety of promotional strategies should be utilized to further raise awareness among grassroots doctors. Additionally, dedicated funding should be well allocated to optimize the healthcare environment at the grassroots level. It is also essential to develop well-defined policy documents and service guidelines for integrated medical and preventive care. Furthermore, targeted training on integrated medical and preventive care should be implemented for grassroots doctors with specific characteristics.

    The Impact of the Jagged1/Notch1 Signalling Pathway on Endothelial-mesenchymal Transition in Idiopathic Pulmonary Fibrosis
    YANG Qifen, ZHAO Huiliang, GUO Yongsheng, QU Jinglian
    2025, 28(25):  3151-3160.  DOI: 10.12114/j.issn.1007-9572.2023.0766
    Asbtract ( )   HTML ( )   PDF (2970KB) ( )  
    Figures and Tables | References | Related Articles | Metrics
    Background

    Idiopathic pulmonary fibrosis (IPF) is a complex global disease with a pathological mechanism that remains poorly understood and for which there is currently no effective treatment. Endothelial-mesenchymal transition (EndMT) , identified as a pathological basis for various chronic vascular diseases, has recently been recognised as a significant risk factor for IPF. However, the related mechanisms have yet to be clarified.

    Objective

    To observe the effects of the Jagged1/Notch1 signalling pathway on EndMT to elucidate the related mechanisms during IPF.

    Methods

    From March to June 2021, human pulmonary arterial endothelial cells (HPAEC) were cultured in vitro. A control group was established using HPAEC with blank serum, while a model group was created by stimulating HPAEC with 5 mg/L TGF-β1 for 72 hours. In the DAPT group, the same TGF-β1 stimulation was followed by the addition of 500 nmol/L Notch signalling inhibitor for 72 hours. Reverse transcription quantitative polymerase chain reaction (RT-PCR) was employed to measure the expression of Notch1, Jagged1, and the CBF1 Promoter (CBF1) mRNA, while Western blotting (WB) was used to assess the protein expressions of Notch1, Jagged1, and CBF1. Co-immunoprecipitation (Co-IP) was conducted to examine the binding of Notch1 intracellular domain protein (NICD1) with CBF1, and the Methylthiazoltetrazolium Colorimetry (MTT) assay was performed to evaluate cell proliferation. Transwell and scratch assays were conducted to measure cell migration ability, and immunofluorescence was used to detect the expression of endothelial cell markers CD31 and VE-cadherin, as well as mesenchymal cell markers fibroblast-specific protein 1 (FSP1) and α-smooth muscle actin (α-SMA) .

    Results

    Statistical analysis revealed significant differences (P<0.05) in the expression levels of Notch1, Jagged1, CBF1 mRNA and proteins, as well as cell proliferation and migration abilities among the three groups. The blank group and DAPT group exhibited lower expressions of Notch1, Jagged1, and CBF1 mRNA and proteins, alongside reduced cell proliferation and migration compared to the model group, with significant differences noted (P<0.05) . Co-IP results indicated discrepancies in the binding of NICD1 and CBF1 among the three groups, with binding inhibited in the blank and DAPT groups, while binding occurred in the model group. Immunofluorescence results demonstrated differences in the expressions of CD31, VE-Cadherin, FSP1, and α-SMA among the 3 groups, where the blank and DAPT groups showed higher expressions of endothelial markers CD31 and VE-Cadherin compared to the model group, while FSP1 and α-SMA expressions were lower.

    Conclusion

    The Jagged1/Notch1 signalling pathway is involved in the EndMT process during IPF, and inhibiting this signalling pathway can suppress EndMT.

    Analysis of Factors Influencing the Retention Intention of Primary Healthcare Workers in China: a Comparison Based on Urban-rural Differences
    CHU Yijing, YAN Yuge, GU Jie, XI Biao, ZHU Shanzhu, HUANG Jiaoling
    2025, 28(25):  3161-3168.  DOI: 10.12114/j.issn.1007-9572.2023.0935
    Asbtract ( )   HTML ( )   PDF (2007KB) ( )  
    Figures and Tables | References | Related Articles | Metrics
    Background

    Currently, there is a growing global demand for healthcare professionals, but the attrition rate of medical personnel is continuously increasing. This makes the retention of medical staff a pressing public health issue.

    Objective

    To investigate the retention intention of primary healthcare workers in urban and rural areas of China and its influencing factors.

    Methods

    This cross-sectional study, conducted from May to October 2022, involved online questionnaires administered to 44 community health centers and 18 township hospitals across 27 provinces and 4 municipalities in China&apos;s mainland. The survey covered demographics, work-related factors, COVID-19 impacts, psychological responses, and retention intention. Multivariate linear regression was used to analyze determinants.

    Results

    A total of 3 769 questionnaires were collected. The survey results showed that the lowest score for intention to stay was (19.8±3.7) in Jiangxi Province, while the highest score was (23.9±3.8) in the Xizang Autonomous Region. Significant positive predictors included advanced age, female gender, marital status, higher monthly income (>5 000 CNY) , <20 years of service, strong institutional support, urban practice location, high job satisfaction, and high personal achievement scores (all P<0.001) . Negative predictors included managerial roles, elevated Patient Health Questionnaire (PHQ) scores, emotional exhaustion, and depersonalization (all P<0.001) . Urban-rural comparisons revealed urban workers prioritized career development pathways and job benefits, whereas rural workers emphasized job security and employment stability (all P<0.001) .

    Conclusion

    The overall retention intention of primary healthcare workers in urban and rural areas of China is at a moderate level. The factors influencing the retention intention of primary healthcare workers in urban and rural areas differ. Corresponding measures can be proposed to improve their retention intention based on these differences.

    Analysis of the Status Quo and Influencing Factors of Health Service Utilization of Rural Residents in Ningxia from the Perspective of Health Poverty Vulnerability
    LI Chunsheng, WANG Youyun, SONG Mingsha, QIAO Hui
    2025, 28(25):  3169-3179.  DOI: 10.12114/j.issn.1007-9572.2023.0475
    Asbtract ( )   HTML ( )   PDF (2329KB) ( )  
    Figures and Tables | References | Related Articles | Metrics
    Background

    In recent years, the direction of China&apos;s health policy has shifted from poverty alleviation to poverty prevention, and rural residents are an important target for poverty prevention in the medical and health fields.

    Objective

    To understand the current status of health service utilization and its influencing factors among rural residents in Ningxia Hui Autonomous Region under different vulnerabilities of health poverty, in order to provide a realistic basis for improving the health service utilization of rural residents and promoting the governance of poverty prevention in the field of medical and health care.

    Methods

    A multistage stratified cluster random sampling method was used to conduct an on-site household survey in four counties of the Ningxia Hui Autonomous Region (Haiyuan, Yanchi, Xiji, and Pengyang counties) in June-July 2022. A questionnaire was used to collect information on the general demographic characteristics of the rural residents, their health status, health service utilization, and household economic situation; a three-stage feasible generalized least squares (FGLS) was used to quantify the vulnerability of the residents to health poverty, and the rural residents were divided into the health poverty vulnerable group and non-health poverty vulnerable group with a cut-off value of 0.5. The multifactorial non-conditional Logistic regression was used in combination with the Anderson model to analyze the utilization of health services by the rural residents of different vulnerabilities to health poverty and the factors affecting them.

    Results

    A total of 17 477 cases of rural residents in Ningxia were included in this study, of which 9 154 cases (52.4%) were male and 8 323 cases (47.6%) were female; the results of health poverty vulnerability measurement and grouping of the rural residents showed that 29.9% (5 229 /17 477) of the residents were vulnerable to health poverty, and 70.1% (12 248/17 477) of the residents were vulnerable to non-health poverty. The results of health service utilization of rural residents showed that the utilization rate of outpatient health services for health poor and vulnerable residents was 3.5% (185 /5 229) , and the utilization rate of outpatient services for non-health poor and vulnerable residents was 4.5% (556 /12 248) ; the residents of different health poor and vulnerable subgroups had different levels of health service utilization in terms of gender, age, literacy level, marital status, type of occupation, number of permanent residents in the family, household annual income, hospitalization due to illness, self-assessed health status, and other characteristic indicators of outpatient health service utilization were compared, and the difference was statistically significant (P<0.05) . The results of multifactorial unconditional Logistic regression analysis showed that for the health poverty vulnerable residents, the occupational grouping of other (OR=1.571, 95%CI=1.084-2.276, P=0.017) , hospitalization due to illness (OR=4.426, 95%CI=3.193-6.136, P<0.001) , and self-assessed health status grouping of fair (OR=11.499, 95%CI=1.549-85.390, P=0.017) and poor (OR=13.256, 95%CI=1.760-99.823, P=0.012) were the facilitators of outpatient health service utilization among rural residents, and literacy level of high school and above (OR=0.256, 95%CI=0.073-0.902, P=0.034) , and household size ≥6 persons (OR=0.264, 95%CI=0.074-0.947, P=0.041) were inhibitors of outpatient health service utilization for rural residents; for the non-healthy poor vulnerable residents, females (OR=1.282, 95%CI=1.063-1.547, P=0.009) , age subgroups of 36 to 55 years (OR=1.689, 95%CI=1.043-2.736, P=0.033) and 56 to 75 years (OR=1.763, 95%CI=1.063-2.926, P=0.028) , and marital status of being in a marriage (OR=2.682, 95%CI=1.464-4.915, P= 0.001) , marital status as divorced, widowed or other (OR=2.782, 95%CI=1.412-5.481, P=0.003) , hospitalized due to illness (OR=2.458, 95%CI=2.019-2.992, P<0.001) , and self-assessed health status as fair (OR=3.555, 95%CI=2.165-5.836, P<0.001) and poor (OR=5.473, 95%CI=3.274-9.151, P<0.001) were the facilitators of outpatient health service utilization among rural residents, and the number of permanent household members was 2-3 (OR=0.578, 95%CI=0.373-0.895, P=0.014) , 4-5 (OR= 0.441, 95%CI=0.274-0.710, P=0.001) , and≥6 persons (OR=0.357, 95%CI=0.209-0.609, P<0.001) were the inhibitors of residents&apos; outpatient health service utilization. Demand factors among the three dimensions of Anderson&apos;s model had the most significant impact on health service utilization among rural residents, and propensity characteristics and enabling resources also had a significant impact.

    Conclusion

    Rural residents of the Ningxia Hui Autonomous Region currently have high health poverty vulnerability and low utilization of outpatient health services, and there is an urgent need for comprehensive measures to prospectively intervene in the health poverty vulnerability of the population, improve the primary health care system, and increase the level of utilization of outpatient health services by rural residents.

    Article·Focus on General Practice Education
    Need Analysis of Medical Students for the Introduction to General Practice Course Based on the Kano Model
    JIAO Shuting, ZHAO Yali
    2025, 28(25):  3180-3186.  DOI: 10.12114/j.issn.1007-9572.2024.0183
    Asbtract ( )   HTML ( )   PDF (2122KB) ( )  
    Figures and Tables | References | Related Articles | Metrics
    Background

    With the national emphasis on the innovative development of medical education, undergraduate teaching as the initiation stage of medical education has also attracted much attention.

    Objective

    Using the Kano model to explore the key elements of the quality reform of the undergraduate course, Introduction to General Practice, and to construct a quality optimization strategy.

    Methods

    Using purposive sampling method, 220 medical students who had completed the course of Introduction to General Practice in the fall semester of 2023 (5-year and long-term students of the class of 2021 in Capital Medical University majoring in clinical medicine, pediatrics, and optometry medicine) were selected as the target respondents. The questionnaire of the course content demand of Introduction to General Practice was used to investigate the students&apos; demand for the course demand status, and carry out attribute categorization for each demand, Better-Worse coefficient analysis and average satisfaction coefficient (ASC) value analysis.

    Results

    From the perspective of all students, among the 44 demand indicators, there were 3 must-be factors, 20 one-dimensional factors and 4 attractive factors. Clinical medicine students had 7 must-be factors, 1 one-dimensional factor and 5 attractive factors in their specific needs; pediatrics and optometry students had 5 must-be factors, 3 one-dimensional factors and 3 attractive factors in their specific needs. 5-year students had 1 must-be factor, 2 one-dimensional factors and 3 attractive factors in their specific needs; and long-term students had 4 must-be factors, 2 one-dimensional factors and 3 attractive factors.

    Conclusion

    Following the principle of making sure to satisfy the must-be factors, prioritizing the one-dimensional factors, selectively satisfying the attractive factors, and appropriately streamlining and adjusting the non-differential factors, the optimization proposals of course quality is constructed.

    Research on Evaluation of Quality Evaluation System of General Practice Faculty in Standardized Clinical Residency Training Bases (General Hospitals)
    ZHAO Wenwen, LI Nuoya, ZHANG Yali, ZHANG Jinjia, ZHANG Min, LIU Hualei, XI Biao, WANG Rongying
    2025, 28(25):  3187-3192.  DOI: 10.12114/j.issn.1007-9572.2023.0929
    Asbtract ( )   HTML ( )   PDF (2037KB) ( )  
    Figures and Tables | References | Related Articles | Metrics
    Background

    United Kingdom, Australia, the United States have established a complete set of applicable teacher quality standards system, teacher access, training process and assessment are strict, while career development and support systems are perfect. There are specialized non-profit organizations that are responsible for the following tasks, developing unified teaching materials, regularly organizing training sessions for general practice (family medicine) faculty, conducting unified assessments and issuing certificates to those who pass the exams, establishing training and assessment systems for faculty members, as well as core indicators for the standardized and systematic construction, evaluating both resident physicians and faculty members based on these indicators. At present, this evaluation system has not yet been established in China.

    Objective

    To construct the model for evaluating the quality of teachers in general practice in standardized clinical residency training bases (general hospitals) based on Delphi method and chromatography analysis.

    Methods

    From June 2022 to August 2023, a research team of 10 researchers was formed. Various materials were included through literature search, and evaluation indicators and standards were extracted. Through thematic group discussions, in-depth analysis of evaluation indicators was conducted and specific indicators and standards were extracted. The comprehensive results were formed into a Delphi expert consultation questionnaire (the first round) . Then select 39 experts from various regions across the country and invite them to participate in 2 or 3 rounds of Delphi expert consultation through questionnaires distributed via email or WeChat. Conduct indicator screening, weight design, and evaluation standard modification on the preliminarily designed evaluation system. An objective assessment should be made regarding the importance of each indicator. The indicators at various levels should be screened step by step, and the analytic hierarchy process (AHP) should be applied to determine the weight of each indicator.

    Results

    After three rounds of expert consultation, a three-level indicator evaluation model was constructed, including 5 first level indicators (teaching conditions, teaching literacy, medical ability, teaching ability, research ability) , 18 second level indicators, 49 third level indicators, and their evaluation standards. The weights of each level of indicator were analyzed and determined. The effective recovery rates of the three rounds of consultation questionnaires were 96.66%, 96.66%, and 100.00%, respectively. The expert authority coefficient was 0.85. The basis for expert judgment was 0.952 3, and the familiarity of experts was 0.910 3. The expert authority coefficient was 0.93. In the first round of consultation, the expert coordination coefficient was 0.21, with a coordination test P<0.05. In the second round of consultation, the expert coordination coefficient was 0.16, with a coordination test P<0.05. In the third round of consultation, the expert coordination coefficient was 0.82, with a coordination test P<0.05. The weights of the first-level indicators were 0.05, 0.25, 0.25, 0.40, and 0.05, respectively.

    Conclusion

    This study provides methods, processes, and experiences for the development and improvement of standardized clinical residency training bases (general hospitals) general practice faculty quality evaluation system. Preliminary establishment of the quality evaluation index system of general practice faculty with teaching ability as the focus.

    Experience of Introducing Programmatic Assessment in General Practice Clinical Reasoning Courses from Constructivism Learning Theory
    ZHAI Jiayan, LU Yuan, PAN Ying, YU Dehua
    2025, 28(25):  3193-3199.  DOI: 10.12114/j.issn.1007-9572.2023.0933
    Asbtract ( )   HTML ( )   PDF (1978KB) ( )  
    Figures and Tables | References | Related Articles | Metrics
    Background

    General practice clinical reasoning is an ability that cannot be directly observed. Currently, there is a lack of objective and comprehensive assessment tools to reflect the trainees&apos; proficiency in this aspect.

    Objective

    Based on the constructivism learning theory, this paper maked a qualitative study on the course experience interview of teachers and students by introducing programmatic assessment (PA) into the course"General Practice Clinical Reasoning", aiming at improving the evaluation system of general practice clinical reasoning and improving the quality of the course and cultivating high-quality talents.

    Methods

    Using purposive sampling, three teaching faculty members and fourteen students who participated in the practical sessions of the course "General Practice Clinical Reasoning" at Tongji University School of Medicine from September to December 2022 were selected as research subjects. Based on constructivist learning theory, an interview outline was developed and semi-structured interviews were conducted. The interview results were analysed using a directed content analysis method.

    Results

    It could be summarized into 4 themes and 10 sub-themes: (1) Context: novelty, interest and practicality of the course. (2) Collaboration: mixed class collaboration, collaboration between teachers and students, collaboration between students. (3) Conversation: multi-source feedback and subjective evaluation. (4) Meaning construction: construct students&apos; clinical reasoning and teachers&apos; ability.

    Conclusion

    From the perspective of constructivism, this paper makes a qualitative study on the curriculum experience of PA introduction. It holds that the context design follows the principle of "expanding information and accelerating knowledge understanding", and collaboration is a breakthrough to the traditional teaching mode and culture of the whole subject, and two-way feedback exchange in the conversation can finally realize the joint construction of teachers and students&apos; abilities.

    Smart Healthcare & Health Informatics Study
    Evolution and Trends of Domestic and International Research Hotspots in the Field of Large Language Models in Medicine Based on CiteSpace
    NIU Ben, ZHU Xiaoqian, YANG Chen, LIANG Wannian, LIU Jue
    2025, 28(25):  3200-3208.  DOI: 10.12114/j.issn.1007-9572.2024.0377
    Asbtract ( )   HTML ( )   PDF (2437KB) ( )  
    Figures and Tables | References | Related Articles | Metrics
    Background

    With advanced language processing abilities and broad potential application scope, large language models (LLMs) such as ChatGPT, are driving a new wave of natural language processing in the medical field.

    Objective

    This study aims to identify research hotspots, topic distribution, and future trends of medical LLMs using bibliometric analysis.

    Methods

    A systematic search was conducted across the Web of Science, CNKI, Wanfang Data, and VIP databases for literature on medical LLMs published between January 2017 and June 2024. CiteSpace software was used to extract thematic keywords and other information from the literature, analyze and compare the evolution, hotspots, and trends of domestic and international research.

    Results

    A total of 1 071 relevant papers were included, revealing that international research mainly focuses on applying artificial intelligence, LLMs, deep learning, and knowledge graphs in medicine. In contrast, domestic research is more limited, focusing on developing Chinese medical question-answering systems and solving unstructured medical data problems.

    Conclusion

    It is recommended to enhance medical data mining, broaden its application in various scenarios, and leverage international experiences in fine-tuning and evaluating LLMs to advance medical LLM development in China.

    The Application of Artificial Intelligence in Psychological Interventions: Effectiveness, Challenges, and Prospects
    WANG Hui, HU Yinhuan, FENG Xiandong, LIU Sha, WANG Yangfan
    2025, 28(25):  3209-3216.  DOI: 10.12114/j.issn.1007-9572.2024.0508
    Asbtract ( )   HTML ( )   PDF (2168KB) ( )  
    References | Related Articles | Metrics

    Artificial intelligence (AI) psychological interventions offer advantages such as real-time delivery, personalization, low stigma, and no geographical limitations, enabling more accurate assessment and intervention for mental health issues, thus addressing the shortcomings of traditional mental health services. While AI has been applied to address various mental health conditions, its practical effectiveness still lacks effective integration. Taking depression and anxiety disorders as an example, this paper reviews the efficacy of AI interventions, including robots, virtual reality, games, and applications. The findings show that these interventions can significantly alleviate depression or anxiety symptoms and improve mental health. However, challenges remain, including data privacy and security concerns, ethical and legal issues, technological limitations, long-term adherence, and cultural adaptability. With technological advancements, AI psychological interventions are expected to expand their application scenarios, integrate multidisciplinary approaches, and foster global collaboration for data sharing and ethical oversight, thereby advancing the intelligent development of mental health services.