Study on the Value of Oligosaccharide Chain and Alpha-fetoprotein for Risk Screening and Diagnosis of Hepatitis B Virus-related Hepatocellular Carcinoma
1. Department of Infectious Diseases, the First Affiliated Hospital of Soochow University, Suzhou 215006, China 2. Sysdiagno Biomedtech Co, Ltd., Taizhou 225300, China 3. Sysdiagno Biomedtech Co, Ltd., Nanjing 210000, China
ZHANG Yun,CAI Xinyi,DING Jingnuo, et al. Study on the Value of Oligosaccharide Chain and Alpha-fetoprotein for Risk Screening and Diagnosis of Hepatitis B Virus-related Hepatocellular Carcinoma[J]. Chinese General Practice, 2024, 27(15): 1855-1860. DOI: 10.12114/j.issn.1007-9572.2023.0239.
张芸,蔡欣奕,丁靖诺等. 寡糖链、甲胎蛋白对乙型肝炎病毒相关肝细胞癌风险筛查与诊断价值研究[J]. 中国全科医学, 2024, 27(15): 1855-1860. DOI: 10.12114/j.issn.1007-9572.2023.0239.
LIUX E, DESMYTERL, GAOC F,et al. N-glycomic changes in hepatocellular carcinoma patients with liver cirrhosis induced by hepatitis B virus[J]. Hepatology,2007,46(5):1426-1435. DOI:10.1002/hep.21855.
FANGM, DEWAELES, ZHAOY P,et al. Serum N-glycome biomarker for monitoring development of DENA-induced hepatocellular carcinoma in rat[J]. Mol Cancer,2010,9(1):1-15. DOI:10.1186/1476-4598-9-215.
[8]
HIGASHIM, YOSHIMURAT, USUIN,et al. A potential serum N-glycan biomarker for hepatitis C virus-related early-stage hepatocellular carcinoma with liver cirrhosis[J]. Int J Mol Sci,2020,21(23):8913. DOI:10.3390/ijms21238913.
[9]
GALLEP R, FOERSTERF, KUDOM,et al. Biology and significance of alpha-fetoprotein in hepatocellular carcinoma[J]. Liver Int,2019,39(12):2214-2229. DOI:10.1111/liv.14223.
TSUCHIYAN. Biomarkers for the early diagnosis of hepatocellular carcinoma[J]. World J Gastroenterol,2015,21(37):10573. DOI:10.3748/wjg.v21.i37.10573.
[12]
STERLINGR K, JEFFERSL, GORDONF,et al. Clinical utility of AFP-L3% measurement in North American patients with HCV-related cirrhosis[J]. Am J Gastroenterology,2007,102(10):2196-2205. DOI:10.1111/j.1572-0241.2007.01405.x.
[13]
FORCEM, PARKG, CHALIKONDAD,et al. Alpha-fetoprotein(AFP)and AFP-L3 is most useful in detection of recurrence of hepatocellular carcinoma in patients after tumor ablation and with low AFP level[J]. Viruses,2022,14(4):775. DOI:10.3390/v14040775.
[14]
SINGALA G, CHANV, GETACHEWY,et al. Predictors of liver transplant eligibility for patients with hepatocellular carcinoma in a safety net hospital[J]. Dig Dis Sci,2012,57(2):580-586. DOI:10.1007/s10620-011-1904-7.
[15]
HUX, CHENR G, WEIQ,et al. The landscape of alpha fetoprotein in hepatocellular carcinoma: where are we?[J]. Int J Biol Sci,2022,18(2):536-551. DOI:10.7150/ijbs.64537.
[16]
LIUZ B, WUM, LIND D,et al. Des-gamma-carboxyprothrombin is a favorable biomarker for the early diagnosis of Alfa-fetoprotein-negative hepatitis B virus-related hepatocellular carcinoma[J]. J Int Med Res,2020,48(2):030006052090257. DOI:10.1177/0300060520902575.
[17]
ZHANGZ G, ZHANGY Y, WANGY Y,et al. Alpha-fetoprotein-L3 and Golgi protein 73 may serve as candidate biomarkers for diagnosing alpha-fetoprotein-negative hepatocellular carcinoma[J]. Onco Targets Ther,2016,9:123-129. DOI:10.2147/OTT.S90732.
GUPTAS. Test characteristics of α-fetoprotein for detecting hepatocellular carcinoma in patients with hepatitis C[J]. Ann Intern Med,2003,139(1):46. DOI:10.7326/0003-4819-139-1-200307010-00012.
[20]
SONGP P, GAOJ J, INAGAKIY,et al. Biomarkers: evaluation of screening for and early diagnosis of hepatocellular carcinoma in Japan and China[J]. Liver Cancer,2013,2(1):31-39. DOI:10.1159/000346220.
[21]
CONGM, OUX J, HUANGJ,et al. A predictive model using N-glycan biosignatures for clinical diagnosis of early hepatocellular carcinoma related to hepatitis B virus[J]. OMICS A J Integr Biol,2020,24(7):415-423. DOI:10.1089/omi.2020.0055.
[22]
GUOL, WANL J, HUY W,et al. Serum N-glycan profiling as a diagnostic biomarker for the identification of hepatitis B virus-associated hepatocellular carcinoma[J]. J Gastrointest Oncol,2022,13(1):344-354. DOI:10.21037/jgo-22-93.