Recent Advances in Cognitive Impairment in Schizophrenia：Stage-specific Features and Interventions

doi:10.12114/j.issn.1007-9572.2021.01.010

Abstract

Abstract: Although cognitive impairment occurs in each stage of schizophrenia，its specific trajectory in the development of schizophrenia is still unclear. We analyzed the overall development and stage-specific features of cognitive impairment in schizophrenia，then clarified its developmental trajectory，summarized that temporal changes of cognitive impairment are relatively insignificant，and reviewed relevant interventions. After that，we inferred that schizophrenia may be a cognitive disease in essence，and recommended that future diagnosis and treatment strategies for schizophrenia should be developed based on prevention，recognition and intervention of cognitive impairment.

Key words: Schizophrenia, Cognitive impairment, Cognitive dysfunction, Intervention, Review

摘要： 认知功能障碍贯穿于精神分裂症发生、发展的全过程，但其在疾病进程中的发展轨迹仍不清楚。本文从精神分裂症不同时期认知功能损害特点的角度出发，讨论了关于精神分裂症认知功能障碍的发生和发展过程，明确其发展轨迹以阐明精神分裂症的性质，并回顾了精神分裂症患者认知功能障碍的干预方式，发现精神分裂症患者的认知功能障碍随时间推移相对稳定，其本质可能为一种认知疾病，今后在临床诊断和治疗中需要从认知功能损害的预防、识别和干预等方面建立新的精神分裂症防控策略。

关键词: 精神分裂症, 认知功能损害, 认知功能障碍, 干预, 综述

WANG Xue，ZHOU Yuqiu，LIU Dongwei，WANG Weiliang，MENG Xiangyu，ZHANG Chunyu. Recent Advances in Cognitive Impairment in Schizophrenia：Stage-specific Features and Interventions　[J]. Chinese General Practice, 2021, 24(32): 4121-4125.

王雪，周郁秋，刘东玮，王伟梁，孟祥宇2张春宇. 精神分裂症不同时期认知功能损害特点及干预方式的研究进展[J]. 中国全科医学, 2021, 24(32): 4121-4125.

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