Abstract: Background Because of the widespread use of percutaneous coronary intervention（PCI），cardiac rehabilitation of patients after PCI has received much attention.With the social development trends and policy orientation，the community has gradually become a key area for the cardiac rehabilitation of patients after PCI，especially in terms of medication adherence，which has improved but still falls short of ideal results. Objective To investigate the current situation of medication adherence among patients after PCI in the community，explore its influencing factors，and propose countermeasures. Methods From May 2021 to May 2022，by convenient sampling，200 eligible patients after PCI from 10 community health service centers in Beijing were recruited into this study. Medication adherence of patients after PCI was evaluated to ues the Morisky medication adherence scale. Those who scored 8 points on the Morisky medication adherence scale were included in the excellent adherence group，and those who scored less than 8 points were included in the general adherence group，and logistic regression analysis was used to explore the influencing factors of medication adherence in patients after PCI. Results A total of 181 valid questionnaires were collected，with a valid recovery rate of 90.5%. The 181 patients ranged in age from 41 to 90 years old，with an average age of（68.6±11.2）years. There were statistically significant differences in age，personal monthly income，burden of taking care of family members，diabetes or not，medication literacy questionnaire scores，PHQ-9 scores and PCI duration between the general adherence group and the excellent adherence group（P<0.05）. Multivariate Logistic regression analysis showed that burden of taking care of family（OR=0.092，95%CI=0.031~0.276），PCI duration（OR=0.882，95%CI=0.794~0.979），medication literacy questionnaire scores（OR=3.044，95%CI=1.881~4.927）and PHQ-9 scores（OR=0.067，95%CI=0.021~0.210）were the factors that influence the medication adherence of patients after PCI（P<0.05）. Conclusion The drug utilization rate of patients after PCI decreased year by year，and the medication adherence was not ideal in general. Affected by factors such as burden of taking care of family members，PCI duration，medication literacy questionnaire scores and depressive state，targeted health management and follow-up should be provided to strengthen the establishment of long-term stable and good doctor-patient relationship which can effectively improve medication adherence among patients after PCI.

Key words: Percutaneous coronary intervention, Secondary prevention drugs for coronary heart disease, Medication adherence, Community, Medication literacy

摘要： 背景 因经皮冠状动脉介入术（PCI）技术的广泛使用，术后患者心脏康复备受关注。随着社会发展趋势和政策导向，社区已逐渐成为PCI患者心脏康复的关键领域，尤其用药依从性方面虽有提升，但效果仍不理想。目的 了解PCI患者社区用药依从性现状，探讨其影响因素并提出对策。方法 于2021年5月—2022年5月，采用便利抽样方法选取北京市10家社区卫生服务中心200例符合条件的PCI术后患者。采用Morisky服药依从性量表评价患者的用药依从性，将Morisky服药依从性量表得分为8分者纳入依从性优秀组，得分为<8分者纳入依从性一般组，采用Logistic回归分析探讨PCI术后患者用药依从性的影响因素。结果 共回收有效问卷181份，问卷有效回收率90.5%。181例患者年龄范围为41~90岁，平均（68.6±11.2）岁，PCI术后患者依从性一般组与依从性优秀组的年龄、个人月收入、家人照顾情况、糖尿病患病情况、药物素养问卷评分、PHQ-9评分、PCI年限比较，差异有统计学意义（P<0.05）；多因素Logistic回归分析结果显示，照顾家人情况（OR=0.092，95%CI=0.031~0.276）、PCI年限（OR=0.882，95%CI=0.794~0.979）、药物素养问卷评分（OR=3.044，95%CI=1.881~4.927）和PHQ-9评分情况（OR=0.067，95%CI=0.021~0.210）是PCI术后患者用药依从性的影响因素（P<0.05）。结论 PCI术后患者药物使用率逐年下降，用药依从性总体不理想。受照顾家人情况、PCI年限、药物素养问卷评分及抑郁状态等因素影响，应针对性提供健康管理和随访内容，加强建立长期稳定且良好医患关系，有效改善患者用药依从性。

关键词: 经皮冠状动脉介入治疗, 冠心病二级预防用药, 用药依从性, 社区, 药物素养