Abstract: Background　Intravenous medication has become an important administration means because of its clear and rapid effect.A small mistake in the process of intravenous administration may lead to serious consequences.So ensuring the safety of medication is the basis of today's medical safety.Objective　To develop a management model for intravenous medication safety using information technology，safeguarding the medication safety of patients.Methods　This study was carried out in Shaoxing People's Hospital during March to September 2019.Participants were randomly recruited from 3 clinical departments（No.2 Hepatobiliopancreatology，Hematology and Cardiothoracic Surgery ）using the original intravenous medication management model during March to May（control group，consisting of 41 537 subgroups），and from other clinical departments（No.1 Hepatobiliopancreatology，No.1 Respiratory Medicine and GI Medicine）using the new management model for intravenous medication safety（developed using the information technology，namely，adding a warning module in the computerized physician order entry system，limiting or reminding the amount of glucose to be used in diabetic patients or allergic drugs to be used in patients，and adding a scanning segment at the end of infusion，realizing the traceability of the whole process of infusion）during July to September（observation group，consisting of 39 132 subgroups）.The overall incidence of the possibilities of making intravenous medication errors（approximate errors in glucose use and drug allergy intervention）and the completion rates of intravenous infusion process based on traceability were compared between the two groups.Results　The overall incidence of approximate errors in glucose use and drug allergy intervention in the observation group was lower than that in the control group（0.02% vs 0.56%，0.03% vs 0.32%，respectively，P<0.05）.The completion rates of intravenous infusion process based on traceability in the control group and observation group were 0 and 97.34%，respectively.Conclusion　Our management model for intravenous medication safety developed based on informatization may reduce the potential unsafe risk factors of intravenous medication，and the possibilities of making intravenous medication errors.Moreover，the traceability of whole process of intravenous infusion may be realized，by which individual responsibility for errors may be distinguished.Furthermore，the application of the model is conducive to enhancing scientific and rational drug use，ensuring the safety of patients，and improving the medical quality continuously.

Key words: Veins；Medication therapy management；Medication systems, hospital；Informatization；Management model for intravenous medication safety；Approximate error；Whole course tracing

摘要： 背景　静脉用药由于疗效明确、起效迅速等，已经成为临床治疗疾病的重要手段，而静脉用药过程中一个小失误就可能导致严重后果，因此确保患者用药安全是当今医疗安全的基础。目的　利用信息化手段构建静脉安全用药管理模式，保障患者安全。方法　2019年6月绍兴市人民医院全院开始实行静脉安全用药管理模式，采用随机数字表法选取2019年3—5月3个临床科室（肝胆胰二科、血液内科、胸心外科）住院患者为对照组（静脉用药共
41 537组），2019年7—9月3个临床科室（肝胆胰一科、呼吸内科一、消化内科）住院患者为观察组（静脉用药共39 132组）。本院利用现代化信息技术，基于信息化构建静脉安全用药管理模式，即在医嘱系统中新增“警示”模块，对糖尿病患者使用葡萄糖或患者使用过敏类药物起到限制或提醒功能，同时增加输液结束扫描，实现静脉输液全程可追溯。比较两组静脉用药近似错误（糖尿病患者用葡萄糖、药物过敏干预近似错误）发生率、静脉输液追溯完整率。结果　观察组糖尿病患者用葡萄糖近似错误发生率、药物过敏干预近似错误发生率低于对照组（0.02%与0.56%，0.03%与0.32%，P<0.05）。对照组静脉输液追溯完整率为0，而观察组静脉输液追溯完整率为97.34%。结论　基于信息化构建的静脉安全用药管理模式可以减少静脉用药的潜在不安全危险因素，减少静脉用药近似错误的发生，有利于实现静脉输液全程可追溯，责任到人，持续质量改进，提高用药的科学性及合理性，保障患者安全，提升医疗质量。

关键词: 静脉, 药物疗法管理, 给药系统, 医院, 信息化, 静脉安全用药管理模式, 近似错误, 全程追溯