Anti-NMDA Receptor Encephalitis Secondary to Tubercular Meningitis：a Case Report and Diagnostic Ideas
1.Chinese Academy of Medical Sciences & Peking Union Medical College，Department of Gastroenterology，Peking Union Medical College Hospital，Beijing 100730，China
2.Chinese Academy of Medical Sciences & Peking Union Medical College，Department of General Internal Medicine，Peking Union Medical College Hospital，Beijing 100730，China
3.Chinese Academy of Medical Sciences & Peking Union Medical College，Department of Infectious Disease，Peking Union Medical College Hospital，Beijing 100730，China
4.Chinese Academy of Medical Sciences & Peking Union Medical College，Department of Neurology，Peking Union Medical College Hospital，Beijing 100730，China
*Corresponding author：ZENG Xuejun，Professor，Chief physician；E-mail：zxjpumch@126.com
［1］VENKATESAN A，BENAVIDES D R.Autoimmune encephalitis and its relation to infection［J］．Curr Neurol Neurosci Rep，2015，15（3）：3．DOI：10.1007/s11910-015-0529-1.
［2］GRESA-ARRIBAS N，TITULAER M J，TORRENTS A，et al．Antibody titres at diagnosis and during follow-up of anti-NMDA receptor encephalitis：a retrospective study［J］．Lancet Neurol，2014，13（2）：167-177．DOI：10.1016/s1474-4422（13）70282-5.
［3］FUKUYAMA T，TAKAHASHI Y，KUBOTA Y，et al．Semi-quantitative analyses of antibodies to N-methyl-d-aspartate type glutamate receptor subunits（GluN2B & GluN1） in the clinical course of Rasmussen syndrome［J］．Epilepsy Res，2015，113：34-43．DOI：10.1016/j.eplepsyres.2015.03.004.
［4］KIZTANIR H，BEKTAS G，YILDIZ E P，et al．Coexisting neuronal autoantibodies among children with demyelinating syndromes［J］．Brain Dev，2017，39（3）：248-251．DOI：10.1016/j.braindev.2016.10.008.
［5］SCHOU M，S?THER S G，BOROWSKI K，et al．Prevalence of serum anti-neuronal autoantibodies in patients admitted to acute psychiatric care［J］．Psychol Med，2016，46（16）：3303-3313．DOI：10.1017/S0033291716002038.
［6］OGAWA E，NAGAI T，SAKUMA Y，et al．Association of antibodies to the NR1 subunit of N-methyl-D-aspartate receptors with neuropsychiatric systemic lupus erythematosus［J］．Mod Rheumatol，2016，26（3）：377-383．DOI：10.3109/14397595.2015.1083163.
［7］SUH-LAILAM B B，HAVEN T R，COPPLE S S，et al．Anti-NMDA-receptor antibody encephalitis：performance evaluation and laboratory experience with the anti-NMDA-receptor IgG assay［J］．Clin Chim Acta，2013，421：1-6．DOI：10.1016/j.cca.2013.02.010.
［8］PRüSS H，FINKE C，H?LTJE M，et al．N-methyl-D-aspartate receptor antibodies in herpes simplex encephalitis［J］．Ann Neurol，2012，72（6）：902-911．DOI：10.1002/ana.23689.
［9］GABLE M S，GAVALI S，RADNER A，et al．Anti-NMDA receptor encephalitis：report of ten cases and comparison with viral encephalitis［J］．Eur J Clin Microbiol Infect Dis，2009，28（12）：1421-1429．DOI：10.1007/s10096-009-0799-0.
［10］PENG Y，LIU X J，PAN S Y，et al．Anti-N-methyl-D-aspartate receptor encephalitis associated with intracranial Angiostrongylus cantonensis infection：a case report［J］．Neurol Sci，2017，38（4）：703-706．DOI：10.1007/s10072-016-2718-3.
［11］GRAUS F，TITULAER M J，BALU R，et al．A clinical approach to diagnosis of autoimmune encephalitis［J］．Lancet Neurol，2016，15（4）：391-404．DOI：10.1016/S1474-4422（15）00401-9.
［12］姚远，彭斌，王晓慧，等．抗N-甲基-D-天冬氨酸受体脑炎前驱期与前驱事件［J］．中华医学杂志，2017，97（19）：1469-1473．DOI：10.3760/cma.j.issn.0376-2491.2017.19.009.
YAO Y，PENG B，WANG X H，et al．Analysis of prodromal phase and prodromal events in anti-N-methyl-D-aspartate receptor encephalitis［J］．National Medical Journal of China，2017，97（19）：1469-1473．DOI：10.3760/cma.j.issn.0376-2491.2017.19.009.
［13］MEYDING-LAMADé U K，OBERLINNER C，RAU P R，et al．Experimental herpes simplex virus encephalitis：a combination therapy of acyclovir and glucocorticoids reduces long-term magnetic resonance imaging abnormalities［J］．J Neurovirol，2003，9（1）：118-125．DOI：10.1080/13550280390173373.
［14］安彦虹，齐志刚，赵志莲，等．抗N-甲基-D-天冬氨酸受体脑炎患者影像学特征分析［J］．中国全科医学，2019，22（15）：1859-1863.DOI：10.12114/j.issn.1007-9572.2018.00.400.
AN Y H，QI Z G，ZHAO Z L，et al．Characteristics of imaging findings on patients with anti-N-methyl-D-aspartate receptor encephalitis［J］．Chinese General Practice，2019，22（15）：1859-1863.DOI：10.12114/j.issn.1007-9572.2018.00.400.
