At present, China is faced with high prevalence of osteoporosis, low awareness rate, low treatment rate, diagnosis and treatment and follow-up management are still lack of normative problems. Osteoporosis can be secondary to multiple systemic diseases and is a multidisciplinary disease, which requires multidisciplinary medical workers to work closely together, give full play to their respective advantages, and develop a complete disease management program. In this paper, the author analyzes the status quo, difficulties and prevention and treatment measures of secondary osteoporosis (SOP), in order to provide effective inspiration for clinical workers in the standardized diagnosis and treatment of SOP.
Secondary osteoporosis (OP) is mostly related to endocrine and metabolic diseases. The growth and development of bone is inseparable from the regulation of the endocrine system. Endocrine and metabolic diseases such as hyperthyroidism, hypogonadism, and hyperprolactinemia can break the balance between bone resorption and bone formation, and increase the risk of osteoporosis and fracture. In order to effectively manage secondary OP caused by endocrine and metabolic diseases, it is particularly important to explore its mechanism, diagnostic methods and treatment options. This article reviews the epidemiological characteristics of secondary osteoporosis in different groups of endocrine and metabolic diseases, the pathogenesis of hormone imbalance and cell signaling pathway abnormalities, the characteristics of bone damage such as bone metabolism indicators and bone mineral density, and the progress in the diagnosis and treatment of secondary osteoporosis, so as to provide reference for the prevention and treatment of secondary osteoporosis in patients with endocrine and metabolic diseases.
Patients with osteoporosis (OP) often suffer from a variety of diseases. In addition to general risk factors such as age, gender, race, comorbidities and related treatments can affect bone metabolism. At present, there are relatively few studies on the association between neurological disorders and OP. Therefore, this article intends to review the epidemiological characteristics, bone loss feature, related pathogenesis and progress of diagnosis and treatment, in order to provide reference for the mechanism of bone damage, OP prevention and anti-osteoporosis treatment in patients with nervous system diseases.
Secondary osteoporosis (OP) is easy to be ignored in clinical practice, especially secondary OP caused by hypertension, coronary heart disease, chronic heart failure, atrial fibrillation and other circulatory system diseases. Due to the complexity of circulatory system diseases and adverse reactions of therapeutic drugs, the risk of secondary OP is often underestimated. Early prevention and treatment of secondary OP is very important to improve the quality of life of patients. The mechanism and treatment scheme of bone metabolism imbalance caused by different types of diseases are different. This article will review the common circulatory system diseases complicated with OP from the aspects of epidemiological characteristics, related risk factors and pathogenesis, changes of bone metabolism and characteristics of bone damage, as well as the progress of diagnosis and treatment, in order to provide reference for the prevention and treatment of circulatory system diseases complicated with OP.
