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    MetaDTA: an Online Application for Diagnostic Test Accuracy Meta-analysis
    YANG Shuihua, YAO Guiying, TIAN Chen, YAN Yilong, LIU Jiayi, WANG Jiajia, TIAN Jinhui, NIU Meng, GE Long
    Chinese General Practice    2025, 28 (08): 1023-1032.   DOI: 10.12114/j.issn.1007-9572.2024.0083
    Abstract338)   HTML10)    PDF(pc) (3179KB)(198)       Save

    MetaDTA is an online, interactive application for Meta-analysis of diagnostic test accuracy studies, which calls on the lme4 and shiny packages in R software to perform the statistical analyses and create an interactive user interface. The application does not require any knowledge of statistics and programming, nor does it require any specialized software to be installed, making it easy to use for users with no specialized statistical knowledge. In this paper, we will focus on the quantification of diagnostic test accuracy, visualisation of results and interactive functions of the MetaDTA platform, and introduce users to the specific operation of the application with examples, aiming to help relevant researchers to complete Meta-analysis of diagnostic accuracy studies, plot summary receiver operating characteristic (SROC) curves, draw the results of the evaluation of the quality of the included studies, and carry out sensitivity analysis.

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    Development of a Short Version of the Health Literacy Scale Based on Classical Test Theory and Item Response Theory
    SUN Xiaonan, CHEN Ke, WU Yunchou, TANG Jingqi, WANG Fei, SUN Xinying, HE Miao, WU Yibo
    Chinese General Practice    2024, 27 (23): 2931-2940.   DOI: 10.12114/j.issn.1007-9572.2023.0072
    Abstract1390)   HTML31)    PDF(pc) (2499KB)(4119)       Save
    Background

    Health literacy is closely associated with health status, most domestic studies tend to use multidimensional and multi-item tools for assessing health literacy, lacking simple and effective assessment methods.

    Objective

    To simplify health literacy scale and conduct psychometric test within the Chinese population.

    Methods

    Adults aged 18 years and above were selected from the "China Family Health Index Survey (2021) " for this investigation. Based on inclusion and exclusion criteria, a total of 7 449 participants were selected and randomly divided into two sample sets, including 3 680 cases in sample set 1 and 3 769 cases in sample set 2. The general information questionnaire, Short-form Health Literacy Questionnaire (HLS-SF12), Perception Social Support Scale (PSSS), and Family Health Scale Short-form (FHS-SF) were administered to the respondents. Classical test theory (CTT) and the Mokken model in item response theory (IRT) were used to screen the original items, and validation analyses such as reliability and validity of the simplified scales were also conducted.

    Results

    A 9-item version (HLS-SF9) and a 4-item version (HLS-SF4) were simplified by using CTT and the Mokken model, respectively. Both the HLS-SF9 and the HLS-SF4 had no ceiling effect or floor effect, and the Cronbach's α coefficients for both were 0.913 and 0.842, with split-half reliabilities of 0.871 and 0.815, respectively. The exploratory factor analysis of HLS-SF4 revealed one common factor, accounting for 67.813% of the cumulative variance, with factor loadings exceeding 0.81 for each item. The confirmatory factor analysis of HLS-SF9 showed that χ2/df was 10.844, goodness of fit index (GFI) was 0.985, adjusted goodness of fit index (AGFI) was 0.971, normative fit index (NFI) was 0.986, comparative fit index (CFI) was 0.987, and root mean squared error of approximation (RMSEA) was 0.051. The correlation analysis demonstrated positive correlation of HLS-SF9 and HLS-SF4 with PSSS (r=0.367, 0.292, P<0.001), as well as FHS-SF (r=0.340, 0.237, P<0.001), respectively. The intraclass correlation coefficients (ICC) (95%CI) for the criterion validity of HLS-SF9 against HLS-SF12 was 0.989 (0.988-0.999), while for HLS-SF4 against HLS-SF12 was 0.892 (0.886-0.899) .

    Conclusion

    The simplified health literacy scales have good reliability and validity, which are reliable and effective tools for assessing the health literacy of the Chinese population. Researchers can choose the scale according to the needs of research precision (HLS-SF9) or assessment time (HLS-SF4) .

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