中国全科医学 ›› 2022, Vol. 25 ›› Issue (33): 4191-4195.DOI: 10.12114/j.issn.1007-9572.2022.0240

• 新进展 • 上一篇    下一篇

正常尿白蛋白水平在多种疾病预测中的研究进展

孙珍珍1,2, 刘欢欢3, 陈开宁3, 楼青青2,*()   

  1. 1.210046 江苏省南京市,南京中医药大学护理学院
    2.570102 海南省海口市,海南医学院第一附属医院
    3.570311 海南省海口市,海南省人民医院内分泌科
  • 收稿日期:2022-02-12 修回日期:2022-04-09 出版日期:2022-11-20 发布日期:2022-07-14
  • 通讯作者: 楼青青
  • 孙珍珍,刘欢欢,陈开宁,等.正常尿白蛋白水平在多种疾病预测中的研究进展[J].中国全科医学,2022,25(33):4191-4195. [www.chinagp.net]
    作者贡献:孙珍珍负责文章的构思与设计,文献、资料的收集,进行论文撰写;刘欢欢、陈开宁负责论文的修订,文章质量的控制及审校;楼青青负责文章的可行性分析,最终版本修订,对论文负责。
  • 基金资助:
    国家重点研发计划(2021YFE0204800); 海南省重点研发计划(ZDYF2021SHFZ236)

New Advances in the Value of the Normal Urinary Albumin as a Predictor of Multiple Diseases

SUN Zhenzhen1,2, LIU Huanhuan3, CHEN Kaining3, LOU Qingqing2,*()   

  1. 1.School of Nursing, Nanjing University of Chinese Medicine, Nanjing 210046, China
    2.The First Affiliated Hospital of Hainan Medical University, Haikou 570102, China
    3.Endocrinology Department, Hainan General Hospital, Haikou 570311, China
  • Received:2022-02-12 Revised:2022-04-09 Published:2022-11-20 Online:2022-07-14
  • Contact: LOU Qingqing
  • About author:
    SUN Z Z, LIU H H, CHEN K N, et al. New advances in the value of the normal urinary albumin as a predictor of multiple diseases[J]. Chinese General Practice, 2022, 25 (33) : 4191-4195.

摘要: 目前,关于正常尿白蛋白水平与相关疾病(包括糖尿病肾病、糖尿病视网膜病变、心血管疾病、代谢综合征等)之间的关系已被逐渐重视,越来越多的研究者也对正常尿白蛋白的范围提出了质疑。本文对正常尿白蛋白水平与不同疾病之间的关系及其可能的机制做一综述,旨在探讨正常尿白蛋白作为疾病预测因子的价值,并为今后正常尿白蛋白阈值的重新界定提供依据。

关键词: 白蛋白尿, 糖尿病肾病, 糖尿病视网膜病变, 心血管疾病, 代谢综合征, 综述

Abstract:

The association of the normal range of urinary albumin and its associated diseases (mainly including diabetic kidney diseases, diabetic retinopathy, cardiovascular disease, and metabolic syndrome) has been an increasing concern, and the range of normal urinary albumin has been questioned by a growing number of scholars. We reviewed the association of the normal range of urinary albumin with the aforementioned diseases and the possible mechanism of actions, to assess the value of normal-range urinary albumin as a predictor of the diseases, and to provide a basis for future redefinition of the threshold for the normal range of urine albumin.

Key words: Albuminuria, Diabetic kidney diseases, Diabetic retinopathy, Cardiovascular diseases, Metabolic syndrome, Review